Results 61 to 70 of about 15,649,594 (245)

Single‐Cell Profiling Reveals a Protective WNT5A‐ATF3‐FOSB Signaling Axis in Hair Follicle Stem Cells During Androgenetic Alopecia

Advanced Science, EarlyView.
Androgenetic alopecia (AGA) is a common form of hair loss with limited treatment options. Silencing of WNT5A signaling, which is widely known as the trigger of the ncWNT signaling pathway, happens in hair follicle stem cells from balding areas. It leads to downregulation of ATF3 and its target FOSB.
Ruiyu Luo, Ke Fang, Changjiang Zhao, Jiachao Xiong, Yuan Zhu, Mingyang Lu, He Yan, Zihan Li, Baojin Wu, Hua Jiang, Yufei Li   +10 more
wiley   +1 more source

Hair follicle dermal cells: a morphological, behavioural and molecular study [PDF]

, 1995
Anatomy and smooth muscle a-actin expression in hair follicles from a variety of animal species (Mink, Polecat, Meerkat, Grey squirrel and stoat) was investigated. Smooth muscle ɑ-actin expression was related to follicle activity. Expression was greatest
Sleeman, Matthew Alexander, Sleeman, M
core  

Vitamin E promotes dermal papilla cell proliferation via the lncRNA2919/STAT1 axis to activate the Hedgehog signaling pathway

Non-coding RNA Research
Hair-follicle development is a key determinant of the quality and yield of Angora rabbit wool. Vitamin E (VE) has antioxidant properties and regulates cell proliferation.
Yinuo Fang, Sen Wang, Chengpeng Cao, Anqi Yang, Jing Zhang, Bohao Zhao, Xinsheng Wu, Yan Liu, Yang Chen   +8 more
doaj   +1 more source

In vitro hair follicle growth model for drug testing

Scientific Reports, 2023
In vitro models of human hair follicle-like tissue could be fundamental tools to better understand hair follicle morphogenesis and hair drug screening.
Tatsuto Kageyama, Hikaru Miyata, Jieun Seo, Ayaka Nanmo, Junji Fukuda   +4 more
doaj   +1 more source

Dual‐Responsive Hydrogels Integrate Bioelectrical Stimulation and Piezo‐Photocatalysis for Regenerative Treatment of Infected Wounds

Advanced Science, EarlyView.
A wireless, dual‐responsive hydrogel (PVA/(PVDF‐TrFE)/BiOClBr@PDA) is developed to promote efficient regeneration of infected wounds by integrating piezoelectric stimulation with piezo‐photocatalytic pathways. Under simultaneous light and ultrasonic stimulation, the hydrogel generates therapeutic electrical cues and reactive oxygen species, disrupting ...
Baoying Dai, Wenxuan Qie, Xiaoye Li, Jingben Zheng, Ao He, Heng Dong, Jiangjiang Yan, Hao Zhang, Ziheng Pan, Hang Yin, Chuyi Zhou, Rui Kong, Hao Wang, Binghan Dai, Yannan Xie, Zhiqun Lin   +15 more
wiley   +1 more source

Molecular and cellular basis of Exogen and Anagen induction [PDF]

, 2007
The hair follicle has the unique capacity to pass through periods of growth, regression and rest before regenerating itself to restart the cycle. This dynamic cycling capacity enables animals to change their coats, and for hair length to be controlled at
Claire Alexandra Higgins,
core  

Synergizing biomaterials and cellular molecular pathways: a new frontier in hair follicle generation

Journal of Translational Medicine
Despite significant advances in our understanding of hair follicle cycling and regeneration, creating fully functional hair follicles with active cycling capabilities remains a considerable challenge for clinical applications. This literature review aims
Amir Bajouri, Nasser Aghdami, Mohammad Ali Nilforoushzadeh   +2 more
doaj   +1 more source

Dermal T cell immunity and key regulatory signaling pathways: Implications in immune-mediated alopecia and hair regeneration

Genes and Diseases
Mammalian hair follicles undergo periodic regeneration, with recent research highlighting the immunological niche as a critical regulator of stem cell activity and hair follicle regeneration.
Nana Tao, Qingru Sun, Yuyuan Ying, Yitao Wang, Jianli Gao   +4 more
doaj   +1 more source

Application and Single‐Cell Regulation Mechanism of Engineered EVs Combined With 4D‐Printed Hydrogel for Infected Burn Repair

Advanced Science, EarlyView.
4D bioprinted hydrogel loaded with FGF2‐modified extracellular vesicles (4D@F‐EVs) targets dermal fibroblasts and elevates local wound FGF2 levels via sustained release of F‐EVs. It activates PI3K‐Akt signaling, restores critical KGF+ fibroblast–KGFR+ keratinocyte crosstalk, enhances robust angiogenesis and collagen deposition to efficiently repair ...
Xiaomin Wang, Xiaoyan Li, Xiao Xu, Kelun Zhang, Fengjiao Yu, Zhen Shang, Nailong Pan, Junlin Lv, Yiwei Xu, Yan Tang, Liang Zhang, Xiaotong Li, Taoyi Wang, Jing Tao, Jiaxu Song, Mengyu Zhang, Xin Ma, Dan Han, Xiaoying Kong, Wenhua Xu   +19 more
wiley   +1 more source

Hair coat characteristics in Friesian heifers in the Netherlands and Kenya : experimental data and a review of literature [PDF]

, 1978
The export of about 2600 Friesian heifers to Kenya between 1971-1973 provided an opportunity of studying the adaptation problems experienced by these heifers.
Udo, H.M.J.
core