Results 81 to 90 of about 56,820 (295)

Hair Follicle Development in Mouse Pluripotent Stem Cell-Derived Skin Organoids

Cell Reports, 2018
Summary: The mammalian hair follicle arises during embryonic development from coordinated interactions between the epidermis and dermis. It is currently unclear how to recapitulate hair follicle induction in pluripotent stem cell cultures for use in ...
Jiyoon Lee, Robert Bӧscke, Pei-Ciao Tang, Byron H. Hartman, Stefan Heller, Karl R. Koehler   +5 more
doaj   +1 more source

Solid Lipid Nanoparticles: A Potential Approach for Dermal Drug Delivery [PDF]

, 2014
Solid lipid nanoparticles (SLNs) have attracted increasing attention during recent years. Due to their unique size dependent properties, lipid nanoparticles offer possibilities to develop new therapeutics.
Conway, Barbara R, Kakadia, Pratibha G.
core   +1 more source

Single‐Cell Dissection of Tumor‐Infiltrating Lymphocytes Reveals Cellular Architecture Predictive of Therapeutic Efficacy in Acral Melanoma

Advanced Science, EarlyView.
Autologous tumor‐infiltrating lymphocyte (TIL) therapy shows promising efficacy in acral melanoma, yet determinants of durable response remain unclear. By integrating single‐cell transcriptomics and TCR sequencing, this study reveals that TIL products enriched for T follicular helper and intermediate exhausted T cells establish persistent clonal ...
Chao Zhang, Wanyi Xiao, Hongru Shen, Fenge Li, Ting Li, Weihong Zhang, Haotian Liu, Ziwei Gao, Hongyu Wang, Xiubao Ren, Kexin Chen, Xiangchun Li, Jilong Yang   +12 more
wiley   +1 more source

Metabolomics reveals metabolites associated with hair follicle cycle in cashmere goats

BMC Veterinary Research
Background The hair follicle is a skin accessory organ that regulates hair development, and its activity varies on a regular basis. However, the significance of metabolites in the hair follicle cycle has long been unknown.
Shengchao Ma, Wenzhi Cao, Xiaolin Ma, Xiaofang Ye, Chongkai Qin, Bin Li, Wenna Liu, Qingwei Lu, Cuiling Wu, Xuefeng Fu   +9 more
doaj   +1 more source

Muc5ac mucin expression during rat skin development [PDF]

, 2015
Some mucin genes have been detected during human embryonic and fetal organ development; however, little is known about mucin expression in epidermal development, neither in humans nor in other species. The present research was developed to explore Muc5ac
Barbeito, Claudio Gustavo, Croce, María Virginia, Ferretti, Valeria, Segal Eiras, Amada   +3 more
core   +2 more sources

Ultrasound‐Activated Bifunctional Piezoelectric Hydrogel Dressings Promote Infected Wound Healing via Regulating Angiogenesis and Lymphangiogenesis

Advanced Science, EarlyView.
This study developed a double‐network hydrogel with piezoelectric properties, exhibiting excellent antibacterial activity and promoting fibroblast migration, angiogenesis, and lymphangiogenesis through piezoelectric stimulation, thereby accelerating the healing of infected chronic wounds.
Xiang Li, Zhen Ding, Zhihua Liu, Hao Chen, Jianyang Shan, Yanxuan Shao, Yaling Yu, Gen Wen   +7 more
wiley   +1 more source

Synergizing biomaterials and cellular molecular pathways: a new frontier in hair follicle generation

Journal of Translational Medicine
Despite significant advances in our understanding of hair follicle cycling and regeneration, creating fully functional hair follicles with active cycling capabilities remains a considerable challenge for clinical applications. This literature review aims
Amir Bajouri, Nasser Aghdami, Mohammad Ali Nilforoushzadeh   +2 more
doaj   +1 more source

In vitro hair follicle growth model for drug testing

Scientific Reports, 2023
In vitro models of human hair follicle-like tissue could be fundamental tools to better understand hair follicle morphogenesis and hair drug screening.
Tatsuto Kageyama, Hikaru Miyata, Jieun Seo, Ayaka Nanmo, Junji Fukuda   +4 more
doaj   +1 more source

Canine recurrent flank alopecia: a synthesis of theory and practice [PDF]

, 2014
Canine recurrent flank alopecia is a non-inflammatory, non-scarring alopecia of unknown etiology and has a visually striking clinical presentation.
Daminet, Sylvie, De Cock, Hilde, Declercq, Jan, Vandenabeele, Sophie   +3 more
core   +2 more sources

Meeting report: a hard look at the state of enamel research. [PDF]

, 2017
The Encouraging Novel Amelogenesis Models and Ex vivo cell Lines (ENAMEL) Development workshop was held on 23 June 2017 at the Bethesda headquarters of the National Institute of Dental and Craniofacial Research (NIDCR).
Bartlett, John D, DenBesten, Pamela, Diekwisch, Thomas Gh, Duverger, Olivier, Joester, Derk, Klein, Ophir D, Kulkarni, Ashok B, Lacruz, Rodrigo S, Millar, Sarah E, Moradian-Oldak, Janet, Pugach, Megan K, Shaw, Wendy, Simmer, James P, Wright, J Timothy   +13 more
core   +1 more source