Results 31 to 40 of about 61,539 (257)
Delivery of DNA‐encoded vaccines and proteins in mice using cutaneous suction‐mediated transfection
FEBS Open Bio, EarlyView.Cutaneous suction‐mediated transfection in mice for delivery of DNA‐encoded vaccines and proteins. A critical limitation of DNA vaccines and other therapeutics is transfection in vivo to produce the encoded antigens or therapeutic proteins. Cutaneous suction‐based methods have demonstrated effectiveness in many animal models and have been successfully ...
Emran O. Lallow +12 more
wiley +1 more source
A Case Report of Hairy Cell Leukemia Presenting Concomitantly with Sweet Syndrome
Case Reports in Medicine, 2014 Hairy cell leukemia and Sweet syndrome are both uncommon hematological diagnoses. We present a patient who was admitted with fevers, pancytopenia, pneumonia, and rash.
Mohammad Alkayem, Waina Cheng
doaj +1 more source
Molecular Plant-Microbe Interactions, 2014 The hairy root, a specialized plant tissue that emerges from a cell transformed with transfer DNA (T-DNA) from Agrobacterium rhizogenes, can be used to study root biology and utilized in biotechnological applications.
Jung-Hao Wang +5 more
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Hairy cell leukemia and pregnancy [PDF]
Терапевтический архив, 2017 The paper presents experience in following up and treating hairy cell leukemia (HCL) during pregnancy. The combination of HCL and pregnancy was observed in 5 patients. The patients’ median age was 35 years (range, 28—42 years).
L S Al-radi +3 more
doaj +1 more source
Case Report: Development of Diffuse Large B Cell Lymphoma a Long Time After Hairy Cell Leukemia
Pathology and Oncology Research, 2022 Hairy cell leukaemia (HCL) is a rare B cell malignancy with an indolent course leading to pancytopaenia due to bone marrow infiltration. It has been proposed that HCL patients are at risk of developing a secondary malignancy, with a marked likelihood of ...
Zsófia F. Nagy +6 more
doaj +1 more source
Genomics of Hairy Cell Leukemia
Journal of Clinical Oncology, 2017 Hairy cell leukemia (HCL) is a chronic mature B-cell neoplasm with unique clinicopathologic features and an initial exquisite sensitivity to chemotherapy with purine analogs; however, the disease relapses, often repeatedly. The enigmatic pathogenesis of HCL was recently clarified by the discovery of its underlying genetic cause, the BRAF-V600E kinase ...
TIACCI, Enrico +3 more
openaire +3 more sources
FEBS Open Bio, EarlyView.Using peripheral blood for determining B‐cell or T‐cell clonality is more reliable when we use cell‐free RNA (cfRNA) because cells release blood significantly more RNA than DNA. Next‐generation sequencing (NGS) of cfRNA allows us to evaluate fragment cfRNA and evaluate clonality reliably without the need for prior determination of the specific dominant
Adam Albitar +11 more
wiley +1 more source
Journal of Applied Hematology, 2015 Plasma cell leukemia (PCL) is defined by the presence of more than 2 × 109/L PCs in the peripheral blood. It is a very rare type of leukemia with poor outcome. In this case, we report a PCL case with peripheral blood morphology of hairy cell leukemia. We
Nahlah Alghasham +3 more
doaj +1 more source
The Liver in Hairy Cell Leukemia
Annals of Internal Medicine, 1980 Excerpt To the editor: The clinical review of Golumb, Catovsky, and Golde (1), based on 71 cases of hairy cell leukemia, stresses its clinical and laboratory characteristics and the prognostic fact...
GEORGOULIAS, V +3 more
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Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level
Aging and Cancer, EarlyView.This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley +1 more source