Results 11 to 20 of about 61,539 (257)

Selective influences in the expressed immunoglobulin heavy and light chain gene repertoire in hairy cell leukemia

open access: yesHaematologica, 2008
Background We previously reported ongoing mutational and isotype switch events in the immunoglobulin (Ig) heavy chain (H) locus in hairy cell leukemia.
Francesco Forconi   +9 more
doaj   +1 more source

Recent advances in understanding and managing hairy cell leukemia [version 1; referees: 4 approved]

open access: yesF1000Research, 2018
Hairy cell leukemia is a rare B-cell malignancy that is characterized by an indolent course. It was initially described as a distinct entity in 1958. Before the establishment of modern treatment, median survival was only 4 years.
Tobias Roider   +2 more
doaj   +1 more source

Cichorium intybus L. Hairy Roots as a Platform for Antimicrobial Activity

open access: yesPharmaceuticals, 2023
Industrial chicory is an important crop for its high dietary fibre content. Besides inulin, chicory taproots contain interesting secondary metabolite compounds, which possess bioactive properties.
Suvi T. Häkkinen   +6 more
doaj   +1 more source

Hairy cell sarcoma [PDF]

open access: yesPostgraduate Medical Journal, 1983
Summary The first case of a hairy cell sarcoma is presented. Subsequent to surgical resection and post-operative radiotherapy the patient has survived two years without systemic evidence of hairy cell leukaemia.
openaire   +2 more sources

The bHLH transcription factor, hairy, refines the terminal cell fate in the Drosophila embryonic trachea.

open access: yesPLoS ONE, 2010
BackgroundThe pair-rule gene, hairy, encodes a basic helix-loop-helix transcription factor and is required for patterning of the early Drosophila embryo and for morphogenesis of the embryonic salivary gland.
Yaoyao Zhan   +3 more
doaj   +1 more source

Neutropenia caused by hairy cell leukemia in a patient with myelofibrosis secondary to polycythemia vera: a case report

open access: yesJournal of Medical Case Reports, 2018
Background Polycythemia vera is a myeloproliferative disease that sometimes evolves to myelofibrosis, causing splenomegaly and neutropenia. In this case report, we describe a patient with polycythemia vera and unexplained neutropenia who later turned out
Andreas Hanssønn Habberstad   +6 more
doaj   +1 more source

Optimization of hairy root culture establishment in Chicory plants (Cichorium intybus) through inoculation by Agrobacterium rhizogenes [PDF]

open access: yesمجله بیوتکنولوژی کشاورزی, 2013
Agrobacterium rhizogenes induced hairy roots gain of the potential of production and accumulation of plant secondary metabolites. In recent decades, many researchers have focused on the biosynthesis of valuable secondary metabolites in hairy roots ...
Sara kabirnotaj   +3 more
doaj   +1 more source

Hairy B-cell lymphoproliferative disorder and its differential diagnosis: a case with long-term follow-up

open access: yesMediterranean Journal of Hematology and Infectious Diseases, 2017
Hairy B-cell lymphoproliferative disorder (HBLD) is one of chronic polyclonal B-cell lymphocytosis. We report a 47-year-old female Japanese patient diagnosed as having HBLD based on lymphocytosis with hairy cell appearance and characteristic phenotypes ...
Kensuke Matsuda   +8 more
doaj   +1 more source

Novel targeted treatments in hairy cell leukemia and other hairy cell-like disorders

open access: yesFrontiers in Oncology, 2022
In the category of mature B-cell neoplasms, splenic B-cell lymphoma and leukemia were clearly identified and include four distinct entities: hairy cell leukemia (HCL), splenic marginal zone lymphoma (SMZL), splenic diffuse red pulp lymphoma (SDRPL) and ...
Elsa Maitre   +2 more
doaj   +1 more source

Flow cytometry: Immunophenotyping in 48 hairy cell leukemia cases and the relevance of fluorescence intensity in CDs expression for diagnosis [PDF]

open access: yesEinstein (São Paulo), 2007
Objectives: To report the experience and the importance of flowcytometry immunophenotyping by measuring the positivity andantigenic expression intensity in the diagnosis of 48 patients withhairy cell leukemia (HCL).
Nydia Strachman Bacal   +8 more
doaj  

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