Results 21 to 30 of about 61,539 (257)
Haematologica, 2012 Hairy cell leukemia has been shown to be strongly associated with the BRAF V600E mutation. We screened 59 unenriched archived bone marrow aspirate and peripheral blood samples from 51 patients with hairy cell leukemia using high resolution melting ...
Piers A. Blombery +7 more
doaj +1 more source
Hairy transcriptional repression targets and cofactor recruitment in Drosophila.
PLoS Biology, 2004 Members of the widely conserved Hairy/Enhancer of split family of basic Helix-Loop-Helix repressors are essential for proper Drosophila and vertebrate development and are misregulated in many cancers.
Daniella Bianchi-Frias +5 more
doaj +1 more source
Hairy Cell Leukemia Variant Masquerading as Acute Leukemia: A Rare Case Report [PDF]
Middle East Journal of CancerThe key purpose of this report is to present an uncommon case of hairy cell leukemia variant (HCLv). HCLv is found to be a striking clinico-pathological condition which encompasses the features of classical hairy cell leukemia (cHCL) as well as B cell ...
Shruthi Swamy +3 more
doaj +1 more source
Tuberculous (TB) Meningitis and Pneumonia in a Case of Hairy Cell Leukemia Treated by 2-CDA [PDF]
International Journal of Hematology-Oncology and Stem Cell Research, 2012 Patients with lymphoproliferative disorders have cellular immune deficiency and are susceptible to typical and atypical mycobacterial infections.Hairy cell leukemia is a B-cell type lymphoproliferative disorder.2-CDA is the choice of treatment for ...
Shahin Nateghi +2 more
doaj +2 more sources
Hairy Cell Leukemia: the good news of a bad disease
Galicia Clínica, 2017 Hairy Cell Leukemia (HCL) is an uncommon chronic B cell Lymphoproliferative disorder characterized by the accumulation of a small mature B cell lymphoid cells with abundant cytoplasm and “hairy” projections within the peripheral blood smear, bone marrow ...
Mónica Seidi +2 more
doaj +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Platinum‐based chemotherapy is known to cause severe and debilitating hearing loss, but unlike cisplatin, the true incidence of carboplatin‐induced hearing loss remains unclear. We evaluated functional hearing outcomes in children receiving carboplatin to determine the incidence and severity of ototoxicity. Procedure We identified a
Aniket Chawla +6 more
wiley +1 more source
Hairy Projections on Non Hairy Cells- A Case Report
JOURNAL OF CLINICAL AND DIAGNOSTIC RESEARCH, 2021 Adult T-Cell Leukaemia/Lymphoma (ATLL) is a mature T-cell neoplasm. It is caused by human retrovirus Human T-cell Lymphotropic Virus Type 1(HTLV-1). The neoplastic cells after monoclonal integration begin to express T-cell associated antigens namely CD2, CD3 and CD5.
Rhituparna Das +2 more
openaire +2 more sources
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
The microbiome in human skin aging
FEBS Letters, EarlyView.Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source