Results 1 to 10 of about 61,539 (257)

Pseudomonocytosis on a Sysmex XN haematology analyser masking the monocytopenia of hairy cell leukaemia in a South African woman [PDF]

African Journal of Laboratory Medicine
Introduction: Hairy cell leukaemia (HCL) is a rare B-cell lymphoproliferative disorder characterised by medium-sized villous lymphocytes (‘hairy cells’) and monocytopenia in the peripheral blood. Automated full blood count (FBC) haematology analysers may
Stephanie J. Kennedy, Anne-Cecilia Van Marle   +1 more
doaj   +2 more sources

Pulmonary damage in a patient with hairy cell leukemia - infectious involvement or hematological disease activity? Case report

Biomedical Papers, 2023
Background. Hairy cell leukemia (HCL) is a rare indolent lymphoproliferative disease with an accumulation of mature B lymphocytes with fine reticular chromatin and cytoplasm with typical hairy-like cytoplasmic projections.
Dominika Ecsiova, Katerina Kamaradova, Marketa Nova, Petr Hoffmann, Petra Rozsivalova, Martin Simkovic, Pavel Zak   +6 more
doaj   +1 more source

Hairy cell leukemia with an aggressive outcome: A case report with a review of the literature

MGM Journal of Medical Sciences, 2023
Hairy cell leukemia (HCL), an uncommon cancer affecting B-lymphocytes primarily in the bone marrow and spleen, is identified by abnormal projections on malignant B cells, which give the illness its name.
Adwaita Mashelkarm, Shirish Khatu, Prakash Dive, S Sudhamani   +3 more
doaj   +1 more source

Case report: A case of classic hairy cell leukemia with CNS involvement treated with vemurafenib

Frontiers in Oncology, 2023
Hairy cell leukemia (HCL) is a rare mature B-cell lymphoproliferative disorder and most often presents as classic hairy cell leukemia. This entity is characterized by an indolent course and the presence of the BRAF V600E mutation.
Anna E. Johnson, Athul Raj Raju, Aasems Jacob, Gerhard C. Hildebrandt   +3 more
doaj   +1 more source

A Very Hairy Case: Marked Leukocytosis in Hairy Cell Leukaemia [PDF]

eJHaem
Stephanie Juané Kennedy, Anne‐Cecilia vanMarle   +1 more
doaj   +2 more sources

Hairy cell lymphoma: a unique presentation of hairy cell leukaemia [PDF]

British Journal of Haematology, 2013
A 39-year-old man with a history of type 1 diabetes, presented with right hip pain on rotation, of approximately 5 years duration. No significant findings were observed on physical examination. A full blood count and peripheral blood film were unremarkable.
Hany, Osman, Trenton, Roth, Jiehao, Zhou
openaire   +3 more sources

The Detection of BRAF-V600E Mutation in Hairy Cell Leukaemia by Polymerase Chain Reaction and Study of its associated Clinicohaematological Parameters

Pakistan Armed Forces Medical Journal, 2022
Objective: To contemplate the occurrence of a rare mutation (BRAF V600E) in the patients having Hairy cell leukemia in our setting, which wouldserve asuseful analytic and diagnostic criteria. Study Design: Analytical cross sectional study.
Muhammad Ijaz Iqbal, Helen Mary Robert, Nabeela Khan, Rafia Mahmood, Ayesha Khurshid, Saleem Ahmed Khan   +5 more
doaj   +1 more source

A Hairy Cell Leukaemia Variant – A Rare Case Report [PDF]

Journal of Clinical and Diagnostic Research, 2013
The aim of the article is to present a rare case of Hairy cell leukaemia variant (HCl-V) which is a distinct clinico-pathological entity with intermediate features between classical HCl (HCl-C) and B-cell prolymphocytic leukaemia.
Pankaj Pande, Balasaheb Ramling Yelikar, Mahesh Kumar U   +2 more
doaj   +1 more source

Constant activation of the RAF-MEK-ERK pathway as a diagnostic and therapeutic target in hairy cell leukemia

Haematologica, 2013
The BRAF-V600E mutation defines genetically hairy cell leukemia among B-cell leukemias and lymphomas. In solid tumors, BRAF-V600E is known to aberrantly activate the oncogenic MEK-ERK pathway, and targeted BRAF and/or MEK inhibitors have shown remarkable
Enrico Tiacci, Gianluca Schiavoni, Maria Paola Martelli, Emanuela Boveri, Roberta Pacini, Alessia Tabarrini, Silvia Zibellini, Alessia Santi, Valentina Pettirossi, Elisabetta Fortini, Stefano Ascani, Luca Arcaini, Giorgio Inghirami, Marco Paulli, Brunangelo Falini   +14 more
doaj   +1 more source

Cytochemistry of hairy cells [PDF]

Cancer, 1980
The peripheral blood of 24 patients with bone marrow biopsy-proven hairy cell leukemia was examined with histochemical methods. Periodic acid-Schiff, acid phosphatase, acid phosphatase with tartrate, alpha naphthyl butyrate esterase, alpha naphthyl acetate esterase, and alpha naphthyl acetate esterase with sodium fluoride inhibition were among the ...
D, Variakojis, J W, Vardiman, H M, Golomb   +2 more
openaire   +2 more sources