Results 191 to 200 of about 46,260 (298)

Single‐Cell Dissection of Tumor‐Infiltrating Lymphocytes Reveals Cellular Architecture Predictive of Therapeutic Efficacy in Acral Melanoma

Advanced Science, EarlyView.
Autologous tumor‐infiltrating lymphocyte (TIL) therapy shows promising efficacy in acral melanoma, yet determinants of durable response remain unclear. By integrating single‐cell transcriptomics and TCR sequencing, this study reveals that TIL products enriched for T follicular helper and intermediate exhausted T cells establish persistent clonal ...
Chao Zhang, Wanyi Xiao, Hongru Shen, Fenge Li, Ting Li, Weihong Zhang, Haotian Liu, Ziwei Gao, Hongyu Wang, Xiubao Ren, Kexin Chen, Xiangchun Li, Jilong Yang   +12 more
wiley   +1 more source

Establishment of Dittrichia viscosa L. Hairy Roots and Improvement of Bioactive Compound Production. [PDF]

Plants (Basel)
Paradiso A, Durante M, Caretto S, De Paolis A.   +3 more
europepmc   +1 more source

Abietane Diterpenoids from the Hairy Roots of Salvia corrugata. [PDF]

Molecules, 2021
Kentsop RAD, Iobbi V, Donadio G, Ruffoni B, De Tommasi N, Bisio A.   +5 more
europepmc   +1 more source

Approaching Scarless Wound Healing: From Passive Anti‐Fibrotic to Proactive and Programmable Pro‐Regenerative Strategies

Advanced Science, EarlyView.
This review outlines the wound healing process and factors influencing scar formation, explores how certain animals and human fetuses achieve scarless skin or tissue regeneration, and details tissue engineering material strategies employed in scarless wound dressings.
Meimei Fu, Zhuoyi Huang, Jintao Li, Yue Li, Zhou Fang, Yiwen Jiang, Keke Wu, Jinshan Guo   +7 more
wiley   +1 more source

Genetic transformation of <i>Primula sieboldii</i> using <i>Agrobacterium rhizogenes</i> and whole-plant regeneration from transgenic hairy roots. [PDF]

Front Plant Sci
Gad K, Huu CN, Plaschil S, Kappel C, Lenhard M.   +4 more
europepmc   +1 more source

The SmMYB36-SmERF6/SmERF115 module regulates the biosynthesis of tanshinones and phenolic acids in salvia miltiorrhiza hairy roots. [PDF]

Hortic Res, 2023
Li Q, Fang X, Zhao Y, Cao R, Dong J, Ma P.   +5 more
europepmc   +1 more source

Antioxidants in hairy root cultures

, 2022
Hrubnyk, I., Yudina, Yu., Malarz, J., Stojakowska, A.   +3 more
openaire   +1 more source

Compensatory Interplay Between Clarin‐1 and Clarin‐2 Deafness‐Associated Proteins Governs Phenotypic Variability in Hearing

Advanced Science, EarlyView.
Functional compensation between clarin‐1 and clarin‐2 in cochlear hair cells. Hearing loss associated with CLRN1 mutations shows striking phenotypic variability; however, the underlying mechanisms remain poorly understood. This study reveals that clarin‐1 and clarin‐2 function cooperatively in cochlear hair cells to sustain mechanoelectrical ...
Maureen Wentling, Aïda Yakhlef Sanchez, Nicolas Thelen, Müge Senarisoy, Maria Hogg, Steven Condamine, Andrea Lelli, Emilia Wysocka, Pranav Patni, Sandrine Vitry, Kerem Yasin Yildizhan, Sébastien Le Gal, Sylvie Nouaille, Michael R. Bowl, Marc Thiry, Didier Dulon, Sedigheh Delmaghani, Aziz El‐Amraoui   +17 more
wiley   +1 more source

In vitro strategy to enhance the production of bioactive polyphenols and caffeoylputrescine in the hairy roots of Physalis peruviana L. [PDF]

Sci Rep
Zhong YJ, Wu SF, Zhang L, Yin ZP, Xie YH, Chen JG.   +5 more
europepmc   +1 more source

One-Step Regeneration of Hairy Roots to Induce High Tanshinone Plants in Salvia miltiorrhiza. [PDF]

Front Plant Sci, 2022
Su Y, Lin C, Zhang J, Hu B, Wang J, Li J, Wang S, Liu R, Li X, Song Z, Wang J.   +10 more
europepmc   +1 more source