Results 181 to 190 of about 656,217 (235)

Hairy Roots

2021
Agrobacterium rhizogenes induces hairy root disease in plants. The neoplastic (cancerous) roots produced by A. rhizogenes infection, when cultured in hormone free medium, show high growth rate and genetic stability. These genetically transformed root cultures can produce levels of secondary metabolites comparable to that of intact plants.
openaire   +1 more source

Targeted metabolic engineering of committed steps improves anti-cancer drug camptothecin production in Ophiorrhiza pumila hairy roots

, 2020
Camptothecin (CPT) is a natural compound with remarkable antitumor activities due to its special mechanism of inhibiting DNA topoisomerase I. Ophiorrhiza pumila was found to produce camptothecin.
M. Shi, Heng Gong, L. Cui, Qiang Wang, Can Wang, Yao Wang, G. Kai   +6 more
semanticscholar   +1 more source

Tanshinone production could be increased by the expression of SmWRKY2 in Salvia miltiorrhiza hairy roots.

Plant Science, 2019
Tanshinones are the main bioactive diterpenes in Salvia miltiorrhiza Bunge, are widely used for treating cardiovascular and cerebrovascular diseases. However, the biosynthetic mechanisms of these compounds have not yet been fully explained. In this study,
Changping Deng, Xiaolong Hao, M. Shi, R. Fu, Yao Wang, Yi Zhang, Wei Zhou, Yue Feng, N. Makunga, G. Kai   +9 more
semanticscholar   +1 more source

Hairy Root-activation Tagging: a High-throughput System for Activation Tagging in Transformed Hairy Roots

Plant Molecular Biology, 2005
Activation tagging is a powerful technique for generating gain-of-function mutants in plants. We developed a new vector system for activation tagging of genes in "transformed hairy roots". The binary vector pHR-AT (Hairy Root-Activation Tagging) and its derivative pHR-AT-GFP contain a cluster of rol (rooting locus) genes together with the right border ...
Hikaru, Seki, Tomoko, Nishizawa, Nobukazu, Tanaka, Yasuo, Niwa, Shigeo, Yoshida, Toshiya, Muranaka   +5 more
openaire   +2 more sources

Chemicals from Roots, Hairy Roots, and Their Application

1999
Plants produce thousands of different compounds through the secondary metabolism pathways. Since many of these products are obtained by direct extraction from plants that are cultivated in the field or some times even collected in their original habitat several factors can alter their yield.
B, Canto-Canché, V M, Loyola-Vargas
openaire   +2 more sources

Pharmaceutical important phenolic compounds overproduction and gene expression analysis in Dracocephalum kotschyi hairy roots elicited by SiO2 nanoparticles

Industrial crops and products (Print), 2019
Dracocephalum kotschyi Boiss. is one of the important threatened traditional species of medicinal herbs; last pharmaceutical research has shown that rosmarinic acid (RA) and methoxylated flavonoids, particularly, xanthomicrol and cirsimaritin of this ...
E. Nourozi, B. Hosseini, Ramin Haji Maleki, B. A. Mandoulakani   +3 more
semanticscholar   +1 more source

Polyprenols in hairy roots of Coluria geoides

Biochemical Society Transactions, 2000
Long-chain polyisoprenoid alcohols built from several up to more than 100 isoprenoid units are common constituents of all living organisms. They were found mostly in plants, bacteria, yeasts and mammalian cells. In vitro hairy root culture of Coluria geoides was obtained from plants transformed with Agrobacterium rhizogenes. Growth was optimal at 0.75%
K, Skorupińska-Tudek, V S, Hung, O, Olszowska, M, Furmanowa, T, Chojnacki, E, Swiezewska   +5 more
openaire   +2 more sources

Flavonoids from Glycyrrhiza pallidiflora hairy root cultures

Phytochemistry, 2001
Glycyrrhiza pallidiflora hairy roots were induced from axenic young plants by direct infection with Agrobacterium rhizogenes. The chemical constituents were then investigated after mass culture. The isoflavone, licoagroisoflavone and the coumestan, licoagroside C, were isolated along with seven known flavonoids.
Wei, Li, Kazuo, Koike, Yoshihisa, Asada, Masao, Hirotani, Hekai, Rui, Takafumi, Yoshikawa, Tamotsu, Nikaido   +6 more
openaire   +3 more sources

Induction of Hairy Roots by Agrobacterium Rhizogenes and Growth of Hairy Roots In Vitro

2003
The bacterial genus Agrobucterium includes two species of considerable interest to plant physiologists and pathologists alike. Infection by virulent strains of A. tumefaciens induces the formation of tumors and infection by A. rhizogenes the proliferation of roots in a wide range of dicotyledenous plants: crown-gall and hairy root diseases are not ...
C S, Hunter, S J, Neill
openaire   +2 more sources

Overexpressing chalcone synthase (CHS) gene enhanced flavonoids accumulation in Glycyrrhiza uralensis hairy roots

Botany Letters, 2019
Flavonoids are key bioactive ingredients in Glycyrrhizia uralensis, a widely used herbal medicine in China. Chalcone synthase (CHS) is the first rate-limiting enzyme involved in the flavonoid biosynthetic pathway.
Yan Yin, Jiaming Hou, Shaokai Tian, Lin Yang, Zhi-xin Zhang, Wen-dong Li, Y. Liu   +6 more
semanticscholar   +1 more source