Results 191 to 200 of about 1,153,625 (334)

Antioxidant and Anti-Inflammatory Activities of Phenolic Acid-Rich Extract from Hairy Roots of Dracocephalum moldavica. [PDF]

Molecules, 2023
Weremczuk-Jeżyna I, Gonciarz W, Grzegorczyk-Karolak I.   +2 more
europepmc   +1 more source

Niche‐Mediated Neural Priming Enables Robust and Scalable Generation of Human Choroid Plexus Organoids

Advanced Science, EarlyView.
Compared to E8, mTeSR1 culture downregulated WNT and TGF‑β signaling, and upregulated neural differentiation pathways, enhancing neural priming. Under skin organoid induction conditions, mTeSR1‑cultured hESCs generated organoids with significantly higher neuroepithelial differentiation.
Zhongliang Chen, Liangxia Jiang, Xianbin Wang, Lili Zhong, Rongcan Luo, Min Su, Liangzhao Chu, Peng Luo   +7 more
wiley   +1 more source

High-efficiency genome-editing, transgene evaluation, and antimicrobial efficacy testing using Citrus medica L. hairy roots. [PDF]

Plant J
Kulshreshtha A, Ramasamy M, Irigoyen S, Padilla CS, Tu CK, Laughlin K, Borneman J, Mandadi KK.   +7 more
europepmc   +1 more source

Production of Two Isomers of Sphaeralcic Acid in Hairy Roots from Sphaeralcea angustifolia. [PDF]

Plants (Basel), 2023
Barrera K, González-Cortazar M, Reyes-Pérez R, Pérez-García D, Herrera-Ruiz M, Arellano-García J, Cruz-Sosa F, Nicasio-Torres P.   +7 more
europepmc   +1 more source

AHR‐Responsive Carbon Dots Orchestrate Skin Wound Healing and Colonic Mucosal Repair via Treg‐Mediated Macrophage Efferocytosis

Advanced Science, EarlyView.
Guided by pharmacophore modeling and molecular docking, aryl hydrocarbon receptor (AHR)‐responsive carbon dots were synthesized. They bind directly to AHR and expand gut‐resident regulatory T (Treg) cells. Treg‐derived C‐C motif chemokine ligand 1 (CCL1) enhances macrophage efferocytosis, creating a pro‐regenetative niche that promotes colonic mucosal ...
Zilu Zhu, Han Zhang, Shuai Lin, Wenqian Zheng, Xin Li, Xiaowei Xu, Ruili Yang   +6 more
wiley   +1 more source

Overproduction of tropane alkaloids in transgenic Hyoscyamus reticulatus hairy roots L. elicited by silicon dioxide nanoparticles and precursor feeding by phenylalanine and putrescine. [PDF]

Sci Rep
Hamdami N, Hosseini B, Hedayati A, Hasani M.   +3 more
europepmc   +1 more source

Evaluation of the In Vivo Anti-Atherosclerotic Activity of Quercetin Isolated from the Hairy Roots of Hedysarum neglectum Ledeb. [PDF]

Life (Basel), 2023
Vesnina A, Milentyeva I, Minina V, Kozlova O, Asyakina L.   +4 more
europepmc   +1 more source

TECTB Variants Reveal Tectorial Membrane Vulnerability in Dominant Non‐Syndromic Hearing Loss

Advanced Science, EarlyView.
TECTB is a non‐collagenous protein of the tectorial membrane – an extracellular matrix of the cochlea. This study identifies dominant missense variants in TECTB linked to human hereditary deafness in two unrelated families. Genetically engineered mice homozygous for one of the variants are profoundly deaf, whereas heterozygous mice have normal hearing ...
Evan B. Hale, Barbara Vona, Richard J. Goodyear, Richard T. Osgood, Jun Shen, Sami S. Amr, Karen Mojica, Michaela A. H. Hofrichter, Jörg Schröder, Sophie Flandin, Paul Gratias, Ricardo Vera‐Monroy, Katherine Callahan, Kerry L. Gudlewski, Rolen Quadros, Masato Ohtsuka, JoAnn McGee, Edward J. Walsh, Cynthia C. Morton, Thomas Haaf, Channabasavaiah Gurumurthy, James E. Saunders, Guy P. Richardson, Artur A. Indzhykulian   +23 more
wiley   +1 more source

Knocking Down miR172f in the Hairy Roots of Grass Pea Increases β-ODAP Content and Induces Global Transcriptomic Reprogramming. [PDF]

Genes (Basel)
Liu X, Zhang X, Bai J, Lv J, Jiang Y, Zhan J, Yang Z, Han R, You T, Ma H, Cao N, Lian R, Wang S, Yue Y, Xu Q.   +14 more
europepmc   +1 more source

Exogenous Melatonin Promotes Glucoraphanin Biosynthesis by Mediating Glutathione in Hairy Roots of Broccoli (Brassica oleracea L. var. italica Planch). [PDF]

Plants (Basel), 2023
Bao J, Yang J, Lu X, Ma L, Shi X, Lan S, Zhao Y, Cao J, Ma S, Li S.   +9 more
europepmc   +1 more source