MeJA-induced hairy roots in Plumbago auriculata L. by RNA-seq profiling and key synthase provided new insights into the sustainable production of plumbagin and saponins. [PDF]
Li Y +8 more
europepmc +1 more source
Production of Bioactive Substances with Antiviral Activity in Nitraria schoberi Hairy Roots Culture
T. V. Zheleznichenko +7 more
openalex +1 more source
This study constructed the first D‐amino acid antimicrobial peptide dataset and developed an AI model for efficient screening of substitution sites, with 80% of candidate peptides showing enhanced activity. The lead peptide dR2‐1 demonstrated potent antimicrobial activity in vitro and in vivo, high stability, and low toxicity.
Yinuo Zhao +14 more
wiley +1 more source
Heterologous expression of <i>AaLac1</i> gene in hairy roots and its role in secondary metabolism under PEG-induced osmotic stress condition in <i>Artemisia annua</i> L. [PDF]
Kumari S +5 more
europepmc +1 more source
CD147/Basigin: From Integrative Molecular Hub to Translational Therapeutic Target
This review conceptualizes CD147 as a fundamental “Energy‐Structure Coupler,” physically bridging metabolic flux (via MCTs) with morphogenetic plasticity (via integrins/MMPs) to drive cancer, infection, and autoimmunity. Addressing the “specificity paradox” that limits current translation, the authors chart a strategic roadmap—spanning logic‐gated ...
Xiang‐Min Yang +2 more
wiley +1 more source
Ectopic expression of BpbHLH9 suggested the presence of a self-activating loop mechanism of clade Ia bHLHs to enhance betulinic acid biosynthesis in <i>Lotus japonicus</i> hairy roots. [PDF]
Suzuki H, Sugano SS, Muranaka T, Seki H.
europepmc +1 more source
An Intelligent Magneto‐Mechanical Platform for Cellular Sensing in 3D Microenvironments
This study presents MagMI, a pioneering machine intelligence‐driven magneto‐mechanical sensing platform. It utilizes magneto‐mechanical arrays and machine learning to achieve label‐free, real‐time monitoring and classification of cellular proliferation dynamics within 3D microenvironments.
Yue Quan +4 more
wiley +1 more source
Artificial Intelligence‐Driven Soft Bioelectronics for Self‐Powered Respiration Monitoring
Artificial intelligence‐driven soft bioelectronics for self powered respiration monitoring based on triboelectric nanogenerators (TENGs), piezoelectric nanogenerators (PENGs), and magnetoelastic generators (MEGs) enable continuous and multi‐scenario respiratory biomechanical data collection. Coupled with machine learning and big data driven diagnostics,
Xinkai Xu, Xiao Xiao, Rui Guo, Jun Chen
wiley +1 more source
Extracellular production of pigment from red beet hairy roots accompanied by oxygen starvation.
Masahiro Kino‐oka, Setsuil Tone
openalex +2 more sources

