Results 111 to 120 of about 8,886,396 (384)

Comparison of Combined Dissipation Behaviors and Dietary Risk Assessments of Thiamethoxam, Bifenthrin, Dinotefuran, and Their Mixtures in Tea

Foods
In the tea-planting process, insecticides are commonly combined, potentially prolonging the pre-harvest interval and heightening the risk of dietary exposure.
Tiancai Wang, Yongzhong Qian, Jieqiong Wang, Xueyan Yin, Qifu Liang, Guangqin Liao, Xiabing Li, Jing Qiu, Yanyang Xu   +8 more
doaj   +1 more source

Integration of single‐cell and bulk RNA‐sequencing data reveals the prognostic potential of epithelial gene markers for prostate cancer

Molecular Oncology, EarlyView.
Prostate cancer is a leading malignancy with significant clinical heterogeneity in men. An 11‐gene signature derived from dysregulated epithelial cell markers effectively predicted biochemical recurrence‐free survival in patients who underwent radical surgery or radiotherapy.
Zhuofan Mou, Lorna W. Harries
wiley   +1 more source

Bioavailability and remineralization rates of sediment-derived dissolved organic carbon from a Baltic Sea depositional area

Frontiers in Marine Science
This pilot study investigated the bioavailability and remineralization kinetics of the sediment-derived dissolved organic carbon (DOC) from the Gdańsk Deep, a depositional area in the Baltic Sea.
Monika Lengier, Katarzyna Koziorowska-Makuch, Beata Szymczycha, Karol Kuliński   +3 more
doaj   +1 more source

Development of a Novel Scaffold of Chitosan, Type IV Collagen and Integrin α3β1 As Alternative Scaffold for Primary Culture of Podocytes

Applied Sciences, 2018
Loss of podocytes has been a main pathology present in renal diseases; the leak of these specialized cells increases the permeability of the glomerular basal membrane (GMB) and protein release affecting the glomeruli, the main structure of the kidney ...
Diana Ginette Zárate-Triviño, Sara Paola Hernández-Martínez, Juan José Bollain-y-Goytia-de-la-Rosa, Moisés Armides Franco-Molina, Eduardo Arturo Elizalde-Peña, Margarita Idalia Hernández-Villegas, Gloria Azucena Rangel-Ochoa, Cristina Rodríguez-Padilla   +7 more
doaj   +1 more source

MET variants with activating N‐lobe mutations identified in hereditary papillary renal cell carcinomas still require ligand stimulation

Molecular Oncology, EarlyView.
MET variants in the N‐lobe of the kinase domain, found in hereditary papillary renal cell carcinoma, require ligand stimulation to promote cell transformation, in contrast to other RTK variants. This suggests that HGF expression in the microenvironment is important for tumor growth in such patients. Their sensitivity to MET inhibitors opens the way for
Célia Guérin, Audrey Vinchent, Marie Fernandes, Isabelle Damour, Agathe Laratte, Rémi Tellier, Gabriella O. Estevam, Jean‐Pascal Meneboo, Céline Villenet, Clotilde Descarpentries, James S. Fraser, Martin Figeac, Alexis B. Cortot, Etienne Rouleau, David Tulasne   +14 more
wiley   +1 more source

Neutrinoless double beta decay constrained by the existence of large extra dimensions

, 2012
We present the possible influence on the half-life of neutrinoless double beta decay coming from the existence of $n$ extra spatial dimensions. The half-life in question depends on the mass of the electron neutrino.
Arkani-Hamed N., MAREK GÓŹDŹ, WIESŁAW A. KAMIŃSKI   +2 more
core   +1 more source

Human FcRn Tissue Expression Profile and Half-Life in PBMCs

Biomolecules, 2019
System-wide quantitative characterization of human neonatal Fc receptor (FcRn) properties is critical for understanding and predicting human PK (pharmacokinetics) as well as the distribution of mAbs and Fc-fusion proteins using PBPK (physiologically ...
Yao-Yun Fan, Vahid Farrokhi, Teresa Caiazzo, Mengmeng Wang, Denise M. O’Hara, Hendrik Neubert   +5 more
doaj   +1 more source

Advances in Therapeutic Fc Engineering – Modulation of IgG-Associated Effector Functions and Serum Half-life

Frontiers in Immunology, 2016
Today, monoclonal immunoglobulin gamma (IgG) antibodies have become a major option in cancer therapy especially for the patients with advanced or metastatic cancers.
A. Saxena, Donghui Wu
semanticscholar   +1 more source

Respiratory complex I‐mediated NAD+ regeneration regulates cancer cell proliferation through the transcriptional and translational control of p21Cip1 expression by SIRT3 and SIRT7

Molecular Oncology, EarlyView.
NAD+ regeneration by mitochondrial complex I NADH dehydrogenase is important for cancer cell proliferation. Specifically, NAD+ is necessary for the activities of NAD+‐dependent deacetylases SIRT3 and SIRT7, which suppress the expression of p21Cip1 cyclin‐dependent kinase inhibitor, an antiproliferative molecule, at the translational and transcriptional
Masato Higurashi, Kazunori Mori, Hidetsugu Nakagawa, Momoko Uchida, Fumihiro Ishikawa, Motoko Shibanuma   +5 more
wiley   +1 more source

Stable Isotope Turnover and Half-Life in Animal Tissues: A Literature Synthesis

PLoS ONE, 2015
Stable isotopes of carbon, nitrogen, and sulfur are used as ecological tracers for a variety of applications, such as studies of animal migrations, energy sources, and food web pathways.
M. J. Zanden, M. Clayton, Eric K. Moody, Eric K. Moody, C. Solomon, B. Weidel   +5 more
semanticscholar   +1 more source