Results 71 to 80 of about 735,542 (308)

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Oscillation Theorems for Second-Order Half-Linear Advanced Dynamic Equations on Time Scales

open access: yesInternational Journal of Differential Equations, 2011
This paper is concerned with the oscillatory behavior of the second-order half-linear advanced dynamic equation (𝑟(𝑡)(𝑥Δ(𝑡))𝛾)Δ+𝑝(𝑡)𝑥𝛾(𝑔(𝑡))=0 on an arbitrary time scale 𝕋 with sup 𝕋=∞, where 𝑔(𝑡)≥𝑡 and ∫∞𝑡𝑜(Δ𝑠/(𝑟1/𝛾(𝑠)))
Shuhong Tang   +2 more
doaj   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

open access: yesMolecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero   +8 more
wiley   +1 more source

Information Transmission using the Nonlinear Fourier Transform, Part I: Mathematical Tools

open access: yes, 2014
The nonlinear Fourier transform (NFT), a powerful tool in soliton theory and exactly solvable models, is a method for solving integrable partial differential equations governing wave propagation in certain nonlinear media.
Kschischang, Frank R.   +1 more
core   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

open access: yesMolecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts   +8 more
wiley   +1 more source

Half-linear differential equations of fourth order: oscillation criteria of solutions [PDF]

open access: hybrid, 2022
Omar Bazighifan   +4 more
openalex   +1 more source

Asymptotic formulas for solutions of half-linear Euler-Weber equation

open access: yesElectronic Journal of Qualitative Theory of Differential Equations, 2008
We establish improved asymptotic formulas for nonoscillatory solutions of the half-linear Euler-Weber type differential equation $$ (\Phi(x'))'+\left[\frac{\gamma_p}{t^p}+\frac{\mu_p}{t^p\log^2 t}\right]\Phi(x)=0, \quad \Phi(x):=|x|^{p-2}x,\quad p>1 ...
Zuzana Pátíková
doaj   +1 more source

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

open access: yesMolecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu   +18 more
wiley   +1 more source

A super-analogue of Kontsevich's theorem on graph homology

open access: yes, 2005
In this paper we will prove a super-analogue of a well-known result by Kontsevich which states that the homology of a certain complex which is generated by isomorphism classes of oriented graphs can be calculated as the Lie algebra homology of an ...
A. Schwarz   +10 more
core   +2 more sources

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