Results 41 to 50 of about 322,584 (266)

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach, Gizem Abaci, Tom Huberty, Axel Lechner, Lukas Käsmann, Jens Ricke, Sophia Stöcklein, Martin Canis, Philipp Baumeister, Marianna Alunni‐Fabbroni   +9 more
wiley   +1 more source

Investigation on radiation shielding parameters of cerrobend alloys

Nuclear Engineering and Technology, 2017
In this study, to determine the most effective alloy for shielding against gamma-rays, the gamma-ray shielding parameters of six types of cerrobend alloys have been investigated.
Borhan Tellili, Youssef Elmahroug, Chedly Souga   +2 more
doaj   +1 more source

Measurement and Research of Intrinsic Filtering of X-Ray Optical Machine

Journal of Isotopes, 2021
The thickness of the inherent filter layer is one of the important performance parameters of the X-ray reference radiation device, and it needs to be quantitatively measured. This research is based on the new version of ISO 4037-1 standard specification,
HANG Zhongbin;LIU Chuanfeng;LIU Yuntao;WEI Kexin;SONG Mingzhe;WANG Hongyu
doaj   +1 more source

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

FEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento, Danniel Pereira‐Figueiredo, Gabriella Grossi de Lima Dias, Gabriel Ferreira dos Santos, Mariana Rodrigues Pereira, Rafael Brito, Karin C Calaza   +6 more
wiley   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

The Radiation Attenuation Property of High-Density Polyethylene Doped with Zinc Oxide as an Alternative Gonadal Shield

Recoletos Multidisciplinary Research Journal
Background: The study investigated the radiation attenuation properties of high-density polyethylene doped with zinc oxide as an alternative to the commercially available gonadal shield in different concentrations.
Sofia Van Antonionni Pumar, Roberto Jr. Tagalog, Stephen Andrie Bitoon, Aaliyah Marie Damalerio, Christie Maureese Espinosa, Gleecyl Ann Pros   +5 more
doaj   +1 more source

Enhanced radiation shielding with galena concrete [PDF]

Nuclear Technology and Radiation Protection, 2015
A new concrete, containing galena mineral, with enhanced shielding properties for gamma sources is developed. To achieve optimized shielding properties, ten types of galena concrete containing different mixing ratios and a reference normal ...
Hadad Kamal, Majidi Hosein, Sarshough Samira   +2 more
doaj   +1 more source

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source

Impacts of micro-size PbO on the gamma-ray shielding performance of polyepoxide resin

e-Polymers, 2023
A series of polyepoxide resins doped by lead oxide with low concentrations were fabricated in order to study the impacts of low PbO concentrations on the fabricated composites’ physical- and radiation-shielding properties.
Alorain Dalal A., Sayyed M. I., Almuqrin Aljawhara H., Mahmoud K. G.   +3 more
doaj   +1 more source

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

FEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana, Avigail Yariv, Tal Oppenheim, Hadar Amartely, Dana Reichmann, Oded Livnah   +5 more
wiley   +1 more source