Results 91 to 100 of about 2,979 (183)

Small RNA Toxin‐Assisted Evolution of GC‐Preferred ErCas12a for Enhanced Genome Targeting Range

Advanced Science, Volume 12, Issue 29, August 7, 2025.
ErCas12a is engineered to target GC‐rich PAMs using a small RNA toxin‐aided positive screening system. The resulting variant, enErCas12a, exhibits an expanded PAM profile and facilitates efficient gene editing in both bacterial and mammalian cells, while preserving high targeting specificity for both canonical and non‐canonical PAM targets.
Zehua Chen, Junyuan Xue, Ziying Wang, Jinyuan Sun, Yinglu Cui, Tong Zhu, Huaiyi Yang, Ming Li, Bian Wu   +8 more
wiley   +1 more source

Bacterioruberin extract from Haloarchaea Haloferax marinum: Component identification, antioxidant activity and anti‐atrophy effect in LPS‐treated C2C12 myotubes

Microbial Biotechnology
Carotenoids are natural pigments utilized as colourants and antioxidants across food, pharmaceutical and cosmetic industries. They exist in carbon chain lengths of C30, C40, C45 and C50, with C40 variants being the most common.
Hyeju Lee, Eui-Sang Cho, C. Hwang, Lei Cao, Mi-Bo Kim, Sang Gil Lee, Myung-Ji Seo   +6 more
semanticscholar   +1 more source

From genomes to function: haloarchaea as model organisms [PDF]

Microbiology, 2006
Haloarchaea are adapted to high-salt environments and accumulate equally high salt concentrations in the cytoplasm. The genomes of representatives of six haloarchaeal genera have been fully or partially sequenced, allowing the analysis of haloarchaeal propertiesin silico.
openaire   +2 more sources

Comparative Genome Analysis of Three Halobacillus Strains Isolated From Saline Environments Reveal Potential Salt Tolerance and Algicidal Mechanisms

Environmental Microbiology Reports, Volume 17, Issue 3, June 2025.
Following the previous complete genome analysis, this research provides the function of new Halobacillus species. Three strains were identified: Halobacillus shinanisalinarum sp. nov. SSTM10‐2T, Halobacillus salinarum sp. nov. SSBR10‐3T, and Halobacillus amylolyticus sp. nov. SSHM10‐5T.
Saru Gurung, Chang‐Muk Lee, Hang‐Yeon Weon, So‐Ra Han, Tae‐Jin Oh   +4 more
wiley   +1 more source

Role of the denitrifying Haloarchaea in the treatment of nitrite-brines.

International microbiology : the official journal of the Spanish Society for Microbiology, 2012
This work was funded by research grants from the Spanish Ministry of Education and Science (BIO2008-00082), Generalitat Valenciana (GV/2011/038) and University of Alicante (GRE0925).
Nájera Fernández, Cindy, Zafrilla, Basilio, Bonete, María-José, Martínez-Espinosa, Rosa María   +3 more
openaire   +3 more sources

First Insights Into the Biological and Physical–Chemical Diversity of Various Salt Ponds of Trapani, Sicily

Environmental Microbiology Reports, Volume 17, Issue 2, April 2025.
This study unveils the diverse biological and physical–chemical characteristics of the salt ponds in Trapani, Sicily, focusing on microbial community structures and environmental parameters across varying salinities. It highlights unique microbial adaptations and the dynamic interactions shaping this Mediterranean hypersaline ecosystem.
Benvenuta Sonia Cusenza, Giuseppe Scelfo, Gabriella Licata, Fanny Claire Capri, Fabrizio Vicari, Rosa Alduina, Valeria Villanova   +6 more
wiley   +1 more source

Exploring the human archaeome: its relevance for health and disease, and its complex interplay with the human immune system

The FEBS Journal, Volume 292, Issue 6, Page 1316-1329, March 2025.
This work investigates the archaeome, an essential segment of the human microbiome, focusing on its relationship with the immune system. Here, we outline the types of archaea across different body areas and underscore possible links to health issues, such as obesity and specific cancers.
Torben Kuehnast, Christina Kumpitsch, Rokhsareh Mohammadzadeh, Thomas Weichhart, Christine Moissl‐Eichinger, Holger Heine   +5 more
wiley   +1 more source

Ferric Sulfate and Proline Enhance Heavy-Metal Tolerance of Halophilic/Halotolerant Soil Microorganisms and Their Bioremediation Potential for Spilled-Oil Under Multiple Stresses

Frontiers in Microbiology, 2018
The aim of this study was to explore the heavy-metal resistance and hydrocarbonoclastic potential of microorganisms in a hypersaline soil. For this, hydrocarbonoclastic microorganisms were counted on a mineral medium with oil vapor as a sole carbon ...
Dina M. Al-Mailem, Mohamed Eliyas, Samir S. Radwan   +2 more
doaj   +1 more source

Halolysin SptA, a Serine Protease, Contributes to Growth-Phase Transition of Haloarchaeon Natrinema sp. J7-2, and Its Expression Involves Cooperative Action of Multiple Cis-Regulatory Elements

Frontiers in Microbiology, 2018
Many haloarchaea produce extracellular subtilisin-like proteases (halolysins) during late log phase; however, the physiological function and regulatory mechanism of growth phase-dependent production of halolysins are unknown.
Moran Li, Jing Yin, Sha Mei, Xuhong Wang, Xiao-Feng Tang, Xiao-Feng Tang, Bing Tang, Bing Tang   +7 more
doaj   +1 more source

Advanced Strategies for Poly(3-hydroxybutyrate-co-3-hydroxyvalerate) Production: PHA Synthase Homologous Overexpression in the Extremophile Haloferax mediterranei

Marine Drugs
Bioplastics such as poly(3-hydroxybutyrate-co-3-hydroxyvalerate) (PHBV) are promising alternatives to conventional plastics. However, the high production cost limits their industrial application.
Alexandra Simica, Yolanda Segovia, Alicia Navarro-Sempere, Rosa María Martínez-Espinosa, Carmen Pire   +4 more
doaj   +1 more source