Results 51 to 60 of about 2,260 (153)

Assessment of Haloferax mediterranei Genome in Search of Copper-Molecular Machinery With Potential Applications for Bioremediation

open access: yesFrontiers in Microbiology, 2022
Heavy metals are essential micronutrients at low concentrations, serving as cofactors for relevant microbial enzymes (i.e., respiratory nitrate and nitrite reductases NADH dehydrogenase-2, amine oxidase, etc.), but they become harmful cellular ...
Marina García Llorca   +2 more
doaj   +1 more source

Microbial exopolysaccharide production by polyextremophiles in the adaptation to multiple extremes

open access: yesFEBS Letters, Volume 599, Issue 23, Page 3417-3443, December 2025.
Polyextremophiles are microorganisms that endure multiple extreme conditions by various adaptation strategies that also include the production of exopolysaccharides (EPSs). This review provides an integrated perspective on EPS biosynthesis, function, and regulation in these organisms, emphasizing their critical role in survival and highlighting their ...
Tracey M Gloster, Ebru Toksoy Öner
wiley   +1 more source

Optimization of Growth and Carotenoid Production by Haloferax mediterranei Using Response Surface Methodology

open access: yesMarine Drugs, 2018
Haloferax mediterranei produces C50 carotenoids that have strong antioxidant properties. The response surface methodology (RSM) tool helps to accurately analyze the most suitable conditions to maximize C50 carotenoids production by haloarchaea.
Zaida Montero-Lobato   +8 more
doaj   +1 more source

Study on the production of high 3HV content PHBV via an open fermentation with waste silkworm excrement as the carbon source by the haloarchaeon Haloferax mediterranei

open access: yesFrontiers in Microbiology, 2022
Silkworm excrement is hard to be degraded or bio-utilized by environmental microorganisms due to its high content of heavy metals and antimicrobial biomacromolecules in mulberry leaves. In traditional Chinese silk industry, the silkworm excrement results
Shuangfeng Cai   +10 more
doaj   +1 more source

An Unexpected Facet of Extremophiles: Their Aesthetic Potential in Artistic Expression

open access: yesMicrobial Biotechnology, Volume 18, Issue 10, October 2025.
In an era marked by environmental challenges and the proliferation of misinformation, the fusion of art and science is a strategy to promote public understanding and appreciation of complex scientific phenomena. We illustrate how the use of extremophiles offers novel avenues for artistic exploration and emphasise the benefits of such interdisciplinary ...
Luis Andrés Yarzábal Rodríguez   +4 more
wiley   +1 more source

Characterization of Polyhydroxybutyrate, PHB, Synthesized by Newly Isolated Haloarchaea Halolamina spp.

open access: yesMolecules, 2022
This work aims to characterize the haloarchaeal diversity of unexplored environmental salty samples from a hypersaline environment on the southern coast of Jeddah, Saudi Arabia, looking for new isolates able to produce polyhydroxyalkanoates (PHAs). Thus,
Nashwa Hagagy   +5 more
doaj   +1 more source

Two Decades of Optogenetic Tools: A Retrospective and a Look Ahead

open access: yesAdvanced Genetics, Volume 6, Issue 3, September 2025.
Optogenetics provides up to millisecond scale, cell type‐specific control of biology using light‐sensitive proteins. This review chronicles two decades of tool development, from microbial rhodopsins and photoactivated enzymes to allosteric switches, surveys broad applications in neuroscience, molecular and cell biology, cardiology, immunology, and ...
Xiao Duan, Mo Zhu, Shiqiang Gao
wiley   +1 more source

A Small RNA Is Linking CRISPR–Cas and Zinc Transport

open access: yesFrontiers in Molecular Biosciences, 2021
The function and mode of action of small regulatory RNAs is currently still understudied in archaea. In the halophilic archaeon Haloferax volcanii, a plethora of sRNAs have been identified; however, in-depth functional analysis is missing for most of ...
Pascal Märkle   +7 more
doaj   +1 more source

Small RNA Toxin‐Assisted Evolution of GC‐Preferred ErCas12a for Enhanced Genome Targeting Range

open access: yesAdvanced Science, Volume 12, Issue 29, August 7, 2025.
ErCas12a is engineered to target GC‐rich PAMs using a small RNA toxin‐aided positive screening system. The resulting variant, enErCas12a, exhibits an expanded PAM profile and facilitates efficient gene editing in both bacterial and mammalian cells, while preserving high targeting specificity for both canonical and non‐canonical PAM targets.
Zehua Chen   +8 more
wiley   +1 more source

Hundreds of novel composite genes and chimeric genes with bacterial origins contributed to haloarchaeal evolution

open access: yesGenome Biology, 2018
Background Haloarchaea, a major group of archaea, are able to metabolize sugars and to live in oxygenated salty environments. Their physiology and lifestyle strongly contrast with that of their archaeal ancestors.
Raphaël Méheust   +5 more
doaj   +1 more source

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