Results 61 to 70 of about 337 (117)

Evolution of lysine and arginine biosynthesis revealed by substrate specificity of lysine biosynthetic enzymes in Thermus thermophilus

open access: yesThe FEBS Journal, Volume 293, Issue 6, Page 1727-1740, March 2026.
Two enzymes from the Thermus thermophilus lysine biosynthetic pathway, LysZ and LysY, unexpectedly exhibit substrate promiscuity. They are able to recognize the LysW intermediates utilized by the ArgW‐mediated arginine route, even though the bacterium already possesses the canonical arginine biosynthetic pathway.
Wenyuan Shi   +3 more
wiley   +1 more source

Exploring the Molecular Machinery of Denitrification in Haloferax mediterranei Through Proteomics

open access: yesFrontiers in Microbiology, 2020
Many proteins and enzymes involved in denitrification in haloarchaea can be inferred to be located between the cytoplasmic membrane and the S-layer, based on the presence of a Tat signal sequence and the orientation of the active site that some of these ...
Javier Torregrosa-Crespo   +5 more
doaj   +1 more source

A Small RNA Is Linking CRISPR–Cas and Zinc Transport

open access: yesFrontiers in Molecular Biosciences, 2021
The function and mode of action of small regulatory RNAs is currently still understudied in archaea. In the halophilic archaeon Haloferax volcanii, a plethora of sRNAs have been identified; however, in-depth functional analysis is missing for most of ...
Pascal Märkle   +7 more
doaj   +1 more source

Characterization and Functional Evaluation of Carotenoids From Haloarcula rubripromontorii BS2

open access: yesMicrobiologyOpen, Volume 15, Issue 1, February 2026.
Fractionation and comprehensive characterization of C50 carotenoids from Haloarcula rubripromontorii BS2, identified all‐trans bacterioruberin as the predominant isomer. The haloarchaeal carotenoid exhibited strong antioxidant activity, photostability in oil and was biocompatible with human keratinocytes, highlighting their potential as sustainable ...
Devika N. Nagar   +3 more
wiley   +1 more source

Reconstructing Environmental and Microbial Ecosystem Changes Across the Permian–Triassic Mass Extinction at Lusitaniadalen, Svalbard

open access: yesPaleoceanography and Paleoclimatology, Volume 41, Issue 2, February 2026.
Abstract The Permian–Triassic environmental crisis triggered fundamental changes in marine ecosystems, culminating in the most severe biodiversity crisis of the Phanerozoic. Yet, the environmental and geochemical conditions governing the crisis and ecosystem recovery remain debated.
S. Z. Buchwald   +17 more
wiley   +1 more source

The degradation of glycosaminoglycans by haloarchaea is apparently a common feature in hypersaline habitats worldwide

open access: yesFrontiers in Microbiology
Recent extensive studies of the functional diversity of extremely halophilic archaea (haloarchaea) have significantly altered the long-held view of this unique group of extremophiles as halophilic heterotrophs utilizing either rich mixtures of amino ...
Dimitry Y. Sorokin   +14 more
doaj   +1 more source

Bacteriocins as a Promising Antimicrobial Strategy Against Multidrug‐Resistant Pathogens: Mechanisms of Action, Applications in Human and Animal Health, and the Food Industry

open access: yesBioMed Research International, Volume 2026, Issue 1, 2026.
The global rise of antimicrobial resistance has significantly increased the difficulty treating infectious agents, creating an urgent need for alternative therapeutic strategies. In this context, bacteriocins have emerged as a promising solution, offering a potential alternative to conventional antibacterial therapies.
Abdo Megra Geda   +6 more
wiley   +1 more source

Microbial exopolysaccharide production by polyextremophiles in the adaptation to multiple extremes

open access: yesFEBS Letters, Volume 599, Issue 23, Page 3417-3443, December 2025.
Polyextremophiles are microorganisms that endure multiple extreme conditions by various adaptation strategies that also include the production of exopolysaccharides (EPSs). This review provides an integrated perspective on EPS biosynthesis, function, and regulation in these organisms, emphasizing their critical role in survival and highlighting their ...
Tracey M Gloster, Ebru Toksoy Öner
wiley   +1 more source

An Unexpected Facet of Extremophiles: Their Aesthetic Potential in Artistic Expression

open access: yesMicrobial Biotechnology, Volume 18, Issue 10, October 2025.
In an era marked by environmental challenges and the proliferation of misinformation, the fusion of art and science is a strategy to promote public understanding and appreciation of complex scientific phenomena. We illustrate how the use of extremophiles offers novel avenues for artistic exploration and emphasise the benefits of such interdisciplinary ...
Luis Andrés Yarzábal Rodríguez   +4 more
wiley   +1 more source

Two Decades of Optogenetic Tools: A Retrospective and a Look Ahead

open access: yesAdvanced Genetics, Volume 6, Issue 3, September 2025.
Optogenetics provides up to millisecond scale, cell type‐specific control of biology using light‐sensitive proteins. This review chronicles two decades of tool development, from microbial rhodopsins and photoactivated enzymes to allosteric switches, surveys broad applications in neuroscience, molecular and cell biology, cardiology, immunology, and ...
Xiao Duan, Mo Zhu, Shiqiang Gao
wiley   +1 more source

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