Results 101 to 110 of about 61,813 (248)

Toxicological analyses of the bone matrix: Successes and challenges

open access: yesArchaeometry, EarlyView.
Abstract This study aimed to conduct an in‐depth and systematic literature review dealing with toxicological analyses on human bone tissue and focusing on the forensic toxicological and archaeotoxicological field. Several studies have focused their research on medical drugs, drugs of abuse, and trace elements on both human cadavers and skeletal remains,
Gaia Giordano   +3 more
wiley   +1 more source

Paliperidone poisoning and measurable plasma concentrations 2.5 years after last administered dose: A case report

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
We report a poisoning with paliperidone palmitate, a once‐monthly, long‐acting injectable antipsychotic. The patient suffered from deep sedation and dystonia. She had been treated with extended release intramuscular paliperidone for several years and had received her last injection 8 days prior to admission.
Mariam Nersesjan   +5 more
wiley   +1 more source

Preclinical models for evaluating psychedelics in the treatment of major depressive disorder

open access: yesBritish Journal of Pharmacology, EarlyView.
Psychedelic drugs have seen a resurgence in interest as a next generation of psychiatric medicines with potential as rapid‐acting antidepressants (RAADs). Despite promising early clinical trials, the mechanisms which underlie the effects of psychedelics are poorly understood.
Laith Alexander   +5 more
wiley   +1 more source

A mechanistic account of striatal dopamine function in human cognition: psychopharmacological studies with cabergoline and haloperidol.

open access: yesBehavioral Neuroscience, 2006
The authors test a neurocomputational model of dopamine function in cognition by administering to healthy participants low doses of D2 agents cabergoline and haloperidol.
M. Frank, R. O’Reilly
semanticscholar   +1 more source

ESG‐1‐60 and ESG‐1‐61: Novel dopamine D3 receptor‐preferring partial agonists/antagonists that inhibit cocaine taking and seeking in rodents

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Preclinical studies suggest that highly selective dopamine D3 receptor (D3R) antagonists or partial agonists hold promise for treating substance use disorders. However, their limited effectiveness in reducing cocaine self‐administration is a major drawback.
Omar Soler‐Cedeño   +9 more
wiley   +1 more source

Acute transaminitis after initial days of starting haloperidol

open access: yesMental Illness, 2019
Haloperidol is a first-generation antipsychotic butyrophenone that is lipophilic, readily absorbed, and extensively metabolized in the liver. The occurrence of elevated liver enzymes with haloperidol is reported to be 2.4% with cases generally occurring ...
Rami Gabriel   +3 more
doaj   +1 more source

Approach to the Management of Gastrointestinal Manifestations in Patients With Phaeochromocytoma and Paraganglioma

open access: yesClinical Endocrinology, EarlyView.
ABSTRACT Objective Managing gastrointestinal symptoms in patients with phaeochromocytoma and paraganglioma (PPGL) is challenging due to the risk of catecholaminergic crisis with many commonly prescribed medications, especially in functional tumours.
Monica Majumder   +5 more
wiley   +1 more source

Quetiapine versus Haloperidol in Controlling Conversion Disorder Symptoms; a Randomized Clinical Trial

open access: yesEmergency, 2017
Introduction: About 5% of visits to emergency departments are made up of conversion disorder cases. This study was designed with the aim of comparing the effectiveness of quetiapine and haloperidol in controlling conversion disorder symptoms.
Saeed Reza Ghanbarizadeh   +6 more
doaj   +1 more source

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