Results 91 to 100 of about 40,180 (256)
Dopamine regulates approach-avoidance in human sensation-seeking.
Background Sensation-seeking is a trait that constitutes an important vulnerability factor for a variety of psychopathologies with high social cost.
Roiser, JP +10 more
core +1 more source
Haloperidol is a typical antipsychotic used to treat schizophrenia and induces dopamine D2 receptor antagonism. Long-term use of haloperidol can reduce brain size in animals and humans; however, the underlying mechanism of this effect remains unclear ...
Hyunsu Kang +3 more
doaj +1 more source
ABSTRACT Interindividual variability (IIV) in drug response complicates both fixed‐dose design and individualized therapy. Understanding how pharmacokinetic (PK) and pharmacodynamic (PD) processes jointly shape this variability is essential, particularly in combination therapy, where multiple interacting pathways influence outcomes. This study employed
Kuteesa R. Bisaso +3 more
wiley +1 more source
Haloperidol-Induced Bronchospasm
A case of haloperidol-induced bronchospasm is described, and possible etiologies are suggested. Since haloperidol is commonly used in the treatment of psychoses, it is important for clinicians to be aware of this potentially lethal yet treatable side ...
Rustom Sethna, Robert Notkin
core +1 more source
Haloperidol versus placebo for schizophrenia [PDF]
Background: Haloperidol was developed in the late 1950s for use in the field of anaesthesia. Research subsequently demonstrated effects on hallucinations, delusions, aggressiveness, impulsiveness and states of excitement and led to the introduction of ...
Irving, Claire B., Adams, Clive E.
core +1 more source
ABSTRACT Background Postoperative complications substantially increase morbidity, mortality and healthcare costs. Understanding prognostic factors is essential for risk stratification, targeted prevention strategies, and development of prediction models.
Anders Peder Højer Karlsen +15 more
wiley +1 more source
ABSTRACT Background Delirium is a frequent complication in comatose Out‐of‐Hospital Cardiac Arrest (OHCA) survivors requiring postresuscitation intensive care and is associated with higher mortality and longer hospitalization. Despite this, there is no established pharmacologic strategy for delirium prevention in OHCA survivors.
Benedikte Liebetrau +12 more
wiley +1 more source
Concurrent Hashimoto's Encephalopathy and Papillary Thyroid Carcinoma: A Case Report
ABSTRACT Background Hashimoto's encephalopathy (HE) is a rare steroid‐responsive autoimmune syndrome. Although HE is associated with anti‐thyroid antibodies, its concurrence with malignant thyroid tumors has rarely been described and its clinical implications remain poorly understood.
Ryo Hara +12 more
wiley +1 more source
DESI-MSI of haloperidol in brain tissue.
A/J and C57BL/6J mice (n = 3 per strain) were treated with haloperidol (10 mg/kg/day IP) for 5 days. Two sagittal sections, which were separated by a distance of 120 μm, were prepared the same brain region of haloperidol-treated mice.
Manhong Wu (688848) +19 more
core +1 more source
Carbamazepine is licensed in the United Kingdom for the treatment of epilepsy, bipolar disorder and trigeminal neuralgia. The related compounds oxcarbazepine and eslicarbazepine are licensed for the treatment of epilepsy. These drugs can cause immune‐mediated hypersensitivity reactions, which typically affect the skin, and can be of variable severity ...
Lucy Galloway +24 more
wiley +1 more source

