Results 101 to 110 of about 43,711 (206)
Clinical Pharmacology &Therapeutics, Volume 120, Issue 4, Page 1081-1091, October 2026.Antipsychotics are often prescribed in the management of behaviors and psychological symptoms of dementia. While the potential harms of antipsychotic use in people with dementia have been established, little is known about the risk associated with antipsychotic drug–drug interactions (DDIs). This study aims to examine the patterns of antipsychotic DDIs
Edward C.Y. Lau +7 more
wiley +1 more source
Pharmacoepidemiology and Drug Safety, Volume 35, Issue 10, October 2026.ABSTRACT Purpose This study aims to assess the risk of metabolic side effects among paediatric new users of antipsychotics in Sweden, focusing on differences between substances and sexes. Methods Children aged 5–17 years, who were new users of antipsychotics between 2014 and 2021, were identified using Swedish national health registers.
Elin Eyfells Kimland +4 more
wiley +1 more source
, 2016 Training dataset for ClearMap, contains 3 half brains from control (saline injected) mice, and 3 half brains from haloperidol (1mg/g) injected ...
Nicolas Renier
core +3 more sources
, 2013 Benchalak Maneeton,1 Narong Maneeton,1 Manit Srisurapanont,1 Kaweesak Chittawatanarat2 1Department of Psychiatry, 2Department of Surgery, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand Background: Atypical antipsychotic drugs may have ...
Maneeton B +3 more
core
DESI-MSI of haloperidol in brain tissue.
, 2015 A/J and C57BL/6J mice (n = 3 per strain) were treated with haloperidol (10 mg/kg/day IP) for 5 days. Two sagittal sections, which were separated by a distance of 120 μm, were prepared the same brain region of haloperidol-treated mice.
Manhong Wu (688848) +19 more
core +1 more source
Haloperidol versus placebo for schizophrenia [PDF]
, 2013 BACKGROUND: Haloperidol was developed in the late 1950s for use in the field of anaesthesia. Research subsequently demonstrated effects on hallucinations, delusions, aggressiveness, impulsiveness and states of excitement and led to the introduction of ...
Adams, Clive E.
core +1 more source
Updated Estimates of Agreement Between Dispensed Medications and Forensic Toxicology in Sweden
Pharmacoepidemiology and Drug Safety, Volume 35, Issue 10, October 2026.ABSTRACT Purpose To present updated estimates from a nationwide Swedish study comparing dispensed medications with forensic toxicological findings (2006–2013), following re‐evaluation of the toxicology dataset to address periods with non‐uniform analytical detection and inconsistent testing.
Heidi Taipale +3 more
wiley +1 more source
Mechanism‐Informed Pharmacotherapy Optimization and Deprescribing: A Redox–Mitochondrial Framework
Pharmacology Research &Perspectives, Volume 14, Issue 5, October 2026.From cumulative drug burden to mitochondrial stress and functional decline. The graphical abstract summarizes the central concept of the review, illustrating how cumulative pharmacotherapy exposure may contribute to redox–mitochondrial stress and thereby reduce biological and functional resilience.
Boštjan Martinc
wiley +1 more source
Atypical antipsychotics in the treatment of schizophrenia: systematic overview and meta-regression analysis [PDF]
, 2000 Objective To develop an evidence base for recommendations on the use of atypical antipsychotics for patients with schizophrenia.Design Systematic overview and meta-regression analyses of randomised controlled trials, as a basis for formal development of ...
Freemantle, Nick +5 more
core +1 more source
Persistence of Haloperidol in Human Brain Tissue
, 2014 OBJECTIVE: After discontinuation of neuroleptic drugs, their antipsychotic and antiparkinsonian effects are still present for a prolonged period. It is not known whether the extended effects of neuroleptic drugs in humans are due to the continued ...
Zöchling, Robert +8 more
core +1 more source