Results 11 to 20 of about 81,339 (261)
Journal of Pharmacological Sciences, 2016 Haloperidol is an antipsychotic drug that inhibits the dopamine D2 receptor among others. Haloperidol also binds the sigma-1 receptor (σ1R) and inhibits it irreversibly. A serious outcome of haloperidol treatment of schizophrenia patients is death due to
Yasuharu Shinoda +5 more
doaj +1 more source
International Journal of Cardiology: Heart & Vasculature, 2020 Patients receiving psychiatric medication, like the antipsychotic drug haloperidol, are at an increased risk of sudden cardiac death (SCD). Haloperidol blocks the cardiac rapidly-activating delayed rectifier potassium current, thereby increasing ...
Stefan M. Sattler +9 more
doaj +1 more source
Haloperidol Attenuates Lung Endothelial Cell Permeability In Vitro and In Vivo
Cells, 2021 We previously reported that claudin-5, a tight junctional protein, mediates lung vascular permeability in a murine model of acute lung injury (ALI) induced by lipopolysaccharide (LPS).
Marco A. Colamonici +3 more
doaj +1 more source
TREC-Rio trial: a randomised controlled trial for rapid tranquillisation for agitated patients in emergency psychiatric rooms [ISRCTN44153243] [PDF]
, 2002 Agitated or violent patients constitute 10% of all emergency psychiatric treatment. Management guidelines, the preferred treatment of clinicians and clinical practice all differ.
A Jablensky +21 more
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Aktivitas Ekstrak Rimpang Kunyit (Curcuma longa L) pada Mencit Parkinson yang Diinduksi Haloperidol
Jurnal Sain Veteriner, 2022 Penyakit Parkinson merupakan penyakit neurodegeneratif dengan gangguan motorik seperti bradikinesia, rigiditas, dan tremor yang dapat mempengaruhi keseimbangan tubuh.
Sapto Yuliani +8 more
doaj +1 more source
A molecular basis for selective antagonist destabilization of dopamine D3 receptor quaternary organization [PDF]
, 2017 The dopamine D3 receptor (D3R) is a molecular target for both first-generation and several recently-developed antipsychotic agents. Following stable expression of this mEGFP-tagged receptor, Spatial Intensity Distribution Analysis indicated that a ...
Caltabiano, Gianluigi +6 more
core +2 more sources
Cell & Bioscience, 2011 Haloperidol is an antipsychotic drug that exerts its' antipsychotic effects by inhibiting dopaminergic neurons. Although the exact pathophysiology of haloperidol extrapyramidal symptoms are not known, the role of reactive oxygen species in inducing ...
Perera Joachim +4 more
doaj +1 more source
Relapse in patients with schizophrenia: a comparison between risperidone and haloperidol [PDF]
Brazilian Journal of Psychiatry, 2003 OBJECTIVES: To compare rates of rehospitalization and time to relapse in risperidone vs. haloperidol-treated schizophrenic patients discharged from the hospital. METHODS: Randomized controlled trial comparing risperidone and haloperidol regarding relapse
Eduardo Pondé de Sena +4 more
doaj +1 more source
IBRO Neuroscience Reports, 2023 Antipsychotic treatment is vital for patients with schizophrenia even in the perinatal period, but the impact at the molecular biological level on offspring is unclear.
Hiroshi Kumon +5 more
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Effects of haloperidol and atypical neuroleptics on psychomotor performance and driving ability in schizophrenic patients - Results from an experimental study [PDF]
, 2003 The influence of antipsychotic treatment on the neuropsychological and psychomotor performance of schizophrenic patients is still a subject of investigation.
Kagerer, S. +3 more
core +1 more source