Results 11 to 20 of about 61,813 (248)

Development in Prescriptions of Contraindicated and Potentially Harmful QT Interval–Prolonging Drugs in a Large Geriatric Inpatient Cohort From 2011 to 2021

open access: yesClinical Pharmacology &Therapeutics, Volume 113, Issue 2, Page 435-445, February 2023., 2023
Regulatory authorities put major emphasis on QT (interval)–prolonging properties of new molecular entities. Product information/Summaries of Product Characteristics (SmPCs) of multiple drugs contain warnings or contraindications regarding QT prolongation, e.g., on coadministration of QT‐prolonging drugs (QT drugs).
Melanie I. Then   +5 more
wiley   +1 more source

Aktivitas Ekstrak Rimpang Kunyit (Curcuma longa L) pada Mencit Parkinson yang Diinduksi Haloperidol

open access: yesJurnal Sain Veteriner, 2022
Penyakit Parkinson merupakan penyakit neurodegeneratif dengan gangguan motorik seperti bradikinesia, rigiditas, dan tremor yang dapat mempengaruhi keseimbangan tubuh.
Sapto Yuliani   +8 more
doaj   +1 more source

Haloperidol Attenuates Lung Endothelial Cell Permeability In Vitro and In Vivo

open access: yesCells, 2021
We previously reported that claudin-5, a tight junctional protein, mediates lung vascular permeability in a murine model of acute lung injury (ALI) induced by lipopolysaccharide (LPS).
Marco A. Colamonici   +3 more
doaj   +1 more source

Recent findings on subjective well‐being and physical, psychiatric, and social comorbidities in individuals with schizophrenia: A literature review

open access: yesNeuropsychopharmacology Reports, Volume 42, Issue 4, Page 430-436, December 2022., 2022
Abstract Aim Care for people with schizophrenia is shifting the locus from long‐stay mental hospitals to nonspecialized community‐based settings. Knowledge on the care is not a sole property of psychiatric specialists. Community healthcare workers who do not specialize in psychiatry are recommended to learn more about schizophrenia.
Yupeng He   +7 more
wiley   +1 more source

Rapid tranquilization for agitated patients in emergency psychiatric rooms: a randomized trial of olanzapine, ziprasidone, haloperidol plus promethazine, haloperidol plus midazolam and haloperidol alone Tranquilização rápida para pacientes agitados nos serviços de emergência psiquiátrica: um ensaio clínico randomisado de olanzapina, ziprasidona, haloperidol mais prometazina, haloperidol mais midazolam e haloperidol em monoterapia

open access: yesBrazilian Journal of Psychiatry, 2011
OBJECTIVE: To compare the effectiveness of intramuscular olanzapine, ziprasidone, haloperidol plus promethazine, haloperidol plus midazolam and haloperidol alone as the first medication(s) used to treat patients with agitation and aggressive behavior ...
Leonardo Baldaçara   +3 more
doaj   +1 more source

Haloperidol and Ziprasidone for Treatment of Delirium in Critical Illness

open access: yesNew England Journal of Medicine, 2018
BACKGROUND There are conflicting data on the effects of antipsychotic medications on delirium in patients in the intensive care unit (ICU). METHODS In a randomized, double‐blind, placebo‐controlled trial, we assigned patients with acute respiratory ...
T. Girard   +31 more
semanticscholar   +1 more source

Bullous pemphigoid in a patient with a neuropsychological disorder and a possible novel drug trigger: A case report and review of the literature

open access: yesSkin Health and Disease, Volume 2, Issue 4, December 2022., 2022
This case emphasises the neuropsychological issues associated with managing complex bullous pemphigoid (BP) cases, a possible novel cause of drug‐induced BP and highlights the likelihood of these issues becoming increasingly prevalent in the future.
Sarah M. Dyson   +3 more
wiley   +1 more source

Haloperidol aggravates transverse aortic constriction-induced heart failure via mitochondrial dysfunction

open access: yesJournal of Pharmacological Sciences, 2016
Haloperidol is an antipsychotic drug that inhibits the dopamine D2 receptor among others. Haloperidol also binds the sigma-1 receptor (σ1R) and inhibits it irreversibly. A serious outcome of haloperidol treatment of schizophrenia patients is death due to
Yasuharu Shinoda   +5 more
doaj   +1 more source

Relapse in patients with schizophrenia: a comparison between risperidone and haloperidol [PDF]

open access: yesBrazilian Journal of Psychiatry, 2003
OBJECTIVES: To compare rates of rehospitalization and time to relapse in risperidone vs. haloperidol-treated schizophrenic patients discharged from the hospital. METHODS: Randomized controlled trial comparing risperidone and haloperidol regarding relapse
Eduardo Pondé de Sena   +4 more
doaj   +1 more source

Sleep quality and quantity determined by polysomnography in mechanically ventilated critically ill patients randomized to dexmedetomidine or placebo

open access: yesActa Anaesthesiologica Scandinavica, Volume 67, Issue 1, Page 66-75, January 2023., 2023
Abstract Background Abnormal sleep is commonly observed in the ICU and is associated with delirium and increased mortality. If sedation is necessary, it is often performed with gamma‐aminobutyric acid agonists such as propofol or midazolam leading to an absence of restorative sleep.
Jakob Oxlund   +5 more
wiley   +1 more source

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