Results 21 to 30 of about 69,108 (161)

Effect of the antipsychotic drug haloperidol on arrhythmias during acute myocardial infarction in a porcine model

open access: yesInternational Journal of Cardiology: Heart & Vasculature, 2020
Patients receiving psychiatric medication, like the antipsychotic drug haloperidol, are at an increased risk of sudden cardiac death (SCD). Haloperidol blocks the cardiac rapidly-activating delayed rectifier potassium current, thereby increasing ...
Stefan M. Sattler   +9 more
doaj   +1 more source

Haloperidol Attenuates Lung Endothelial Cell Permeability In Vitro and In Vivo

open access: yesCells, 2021
We previously reported that claudin-5, a tight junctional protein, mediates lung vascular permeability in a murine model of acute lung injury (ALI) induced by lipopolysaccharide (LPS).
Marco A. Colamonici   +3 more
doaj   +1 more source

Retrospective Study of Midazolam Protocol for Prehospital Behavioral Emergencies [PDF]

open access: yes, 2020
Introduction: Agitated patients in the prehospital setting pose challenges for both patient care and emergency medical services (EMS) provider safety. Midazolam is frequently used to control agitation in the emergency department setting; however, limited
Huebinger, Ryan M.   +7 more
core   +1 more source

Effects of gestational haloperidol exposure on mRNA expressions related to glutamate and GABA receptors in offspring

open access: yesIBRO Neuroscience Reports, 2023
Antipsychotic treatment is vital for patients with schizophrenia even in the perinatal period, but the impact at the molecular biological level on offspring is unclear.
Hiroshi Kumon   +5 more
doaj   +1 more source

Effects of haloperidol and atypical neuroleptics on psychomotor performance and driving ability in schizophrenic patients - Results from an experimental study [PDF]

open access: yes, 2003
The influence of antipsychotic treatment on the neuropsychological and psychomotor performance of schizophrenic patients is still a subject of investigation.
Kagerer, S.   +3 more
core   +1 more source

Neuroprotective Effects of Alpha Lipoic Acid on Haloperidol-Induced Oxidative Stress in the Rat Brain

open access: yesCell & Bioscience, 2011
Haloperidol is an antipsychotic drug that exerts its' antipsychotic effects by inhibiting dopaminergic neurons. Although the exact pathophysiology of haloperidol extrapyramidal symptoms are not known, the role of reactive oxygen species in inducing ...
Perera Joachim   +4 more
doaj   +1 more source

Relapse in patients with schizophrenia: a comparison between risperidone and haloperidol [PDF]

open access: yesBrazilian Journal of Psychiatry, 2003
OBJECTIVES: To compare rates of rehospitalization and time to relapse in risperidone vs. haloperidol-treated schizophrenic patients discharged from the hospital. METHODS: Randomized controlled trial comparing risperidone and haloperidol regarding relapse
Eduardo Pondé de Sena   +4 more
doaj   +1 more source

Antipsychotic Response in the First Week Predicts Later Efficacy [PDF]

open access: yes, 2012
Background and Aims: Time of onset of antipsychotic action is still a debated matter. We aimed to replicate and extend previous findings that early response can predict subsequent non-response.
Andrisano, Costanza   +7 more
core   +1 more source

Propionate Protects Haloperidol-Induced Neurite Lesions Mediated by Neuropeptide Y

open access: yesFrontiers in Neuroscience, 2018
Haloperidol is a commonly used antipsychotic drug for treating schizophrenia. Clinical imaging studies have found that haloperidol can cause volume loss of human brain tissue, which is supported by animal studies showing that haloperidol reduces the ...
Minmin Hu   +9 more
doaj   +1 more source

Clozapine as add-on medication in the maintenance treatment of bipolar and schizoaffective disorders - A case series [PDF]

open access: yes, 2002
Atypical neuroleptics are increasingly used in the treatment of bipolar and schizoaffective disorders. Currently, numerous controlled short-term studies are available for clozapine, olanzapine, risperidone or quetiapine, but long-term data are still ...
Amann, B.   +5 more
core   +1 more source

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