Rapid tranquilization for agitated patients in emergency psychiatric rooms: a randomized trial of olanzapine, ziprasidone, haloperidol plus promethazine, haloperidol plus midazolam and haloperidol alone Tranquilização rápida para pacientes agitados nos serviços de emergência psiquiátrica: um ensaio clínico randomisado de olanzapina, ziprasidona, haloperidol mais prometazina, haloperidol mais midazolam e haloperidol em monoterapia [PDF]
Brazilian Journal of Psychiatry, 2011 OBJECTIVE: To compare the effectiveness of intramuscular olanzapine, ziprasidone, haloperidol plus promethazine, haloperidol plus midazolam and haloperidol alone as the first medication(s) used to treat patients with agitation and aggressive behavior ...
Leonardo Baldaçara +3 more
doaj +5 more sources
Haloperidol and Ziprasidone for Treatment of Delirium in Critical Illness [PDF]
New England Journal of Medicine, 2018 BACKGROUND: There are conflicting data on the effects of antipsychotic medications on delirium in patients in the intensive care unit (ICU). METHODS: In a randomized, double-blind, placebo-controlled trial, we assigned patients with acute ...
Timothy D Girard +2 more
exaly +3 more sources
Effects of Haloperidol on Cardiac Histamine H2 Receptors and β-Adrenoceptors in Isolated Mouse and Human Atrial Preparations [PDF]
NeuroSciThe antipsychotic drug haloperidol is found on the WHO list of essential drugs. In vitro, haloperidol demonstrates binding affinity for various receptors, including histamine H2 receptors (H2Rs).
Jonas M. A. Schlicht +4 more
doaj +2 more sources
Borneo Journal of Pharmacy, 2021 Schizophrenia is a psychiatric disorder that requires antipsychotics therapy. Antipsychotics cause many side effects, including orthostatic hypotension.
Noor Cahaya +2 more
doaj +1 more source
Differential changes in QTc duration during in-hospital haloperidol use. [PDF]
PLoS ONE, 2011 AIMS: To evaluate changes in QT duration during low-dose haloperidol use, and determine associations between clinical variables and potentially dangerous QT prolongation. METHODS: In a retrospective cohort study in a tertiary university teaching hospital
Marieke T Blom +9 more
doaj +1 more source
Discover Mental Health, 2022 Objectives The duration of administration (e.g., subchronic or chronic) of haloperidol may influence its adverse effects. We studied the effects of duration of administration of haloperidol on body weight and fasting blood sugar (FBS).
Jaiyeola Abiola Kajero +4 more
doaj +1 more source
Acute Extrapyramidal Side Effects from Smoked Haloperidol
Case Reports in Psychiatry, 2021 Introduction. Haloperidol is a dopamine receptor antagonist used to treat patients with psychotic disorders. Especially at high doses, haloperidol carries a higher risk of extrapyramidal symptoms (EPS) compared to second-generation antipsychotics.
Angeline Pham +2 more
doaj +1 more source
Journal of Toxicology, 2022 Haloperidol is a first-generation antipsychotic drug that has several indications in a wide range of mental conditions. The extensive prescription of haloperidol is correlated with some less-known adverse effects such as genotoxicity.
Ehsan Zamani +5 more
doaj +1 more source
Establishing gold standard approaches to rapid tranquillisation: a review and discussion of the evidence on the safety and efficacy of medications currently used [PDF]
, 2008 Background: Rapid tranquillisation is used when control of agitation, aggression or excitement is required. Throughout the UK there is no consensus over the choice of drugs to be used as first line treatment.
Branford, David +5 more
core +1 more source
Journal of Pharmacological Sciences, 2016 Haloperidol is an antipsychotic drug that inhibits the dopamine D2 receptor among others. Haloperidol also binds the sigma-1 receptor (σ1R) and inhibits it irreversibly. A serious outcome of haloperidol treatment of schizophrenia patients is death due to
Yasuharu Shinoda +5 more
doaj +1 more source