Results 11 to 20 of about 43,711 (206)

Evaluation of haloperidol decanoate initiation dosing in inpatients with serious mental illness [PDF]

Mental Health Clinician
Introduction Manufacturer labeling for haloperidol decanoate recommends an initial dose of 10 to 20 times the daily oral dose; however, significant heterogeneity in dosing practices exists.
Grace Lim, Albert Ngo, Tien Cam Le, Farah Khorassani, PharmD, BCPP, FAAPP   +3 more
doaj   +2 more sources

Rapid tranquilization for agitated patients in emergency psychiatric rooms: a randomized trial of olanzapine, ziprasidone, haloperidol plus promethazine, haloperidol plus midazolam and haloperidol alone Tranquilização rápida para pacientes agitados nos serviços de emergência psiquiátrica: um ensaio clínico randomisado de olanzapina, ziprasidona, haloperidol mais prometazina, haloperidol mais midazolam e haloperidol em monoterapia [PDF]

Brazilian Journal of Psychiatry, 2011
OBJECTIVE: To compare the effectiveness of intramuscular olanzapine, ziprasidone, haloperidol plus promethazine, haloperidol plus midazolam and haloperidol alone as the first medication(s) used to treat patients with agitation and aggressive behavior ...
Leonardo Baldaçara, Marsal Sanches, Daniel Cruz Cordeiro, Andrea Parolin Jackowski   +3 more
doaj   +2 more sources

Acute Extrapyramidal Side Effects from Smoked Haloperidol

Case Reports in Psychiatry, 2021
Introduction. Haloperidol is a dopamine receptor antagonist used to treat patients with psychotic disorders. Especially at high doses, haloperidol carries a higher risk of extrapyramidal symptoms (EPS) compared to second-generation antipsychotics.
Angeline Pham, Joo-Young Lee, Christopher W. T. Miller   +2 more
doaj   +2 more sources

Do Brain Extracellular Fluid Concentrations Predict PET-Inferred Receptor Occupancy in Human CNS? A Mechanistic Model-Based Analysis of Dopamine D2 Receptor Ligands. [PDF]

Clin Pharmacol Ther
A mechanistic CNS PBPK model framework was applied to eight antipsychotic D2 receptor ligands, comparing brain extracellular fluid (brainECF) and brain cell membrane (brainM) as biophase for predicting human receptor occupancy compared against PET neuroimaging data. BrainM concentrations showed improved agreement with PET‐derived receptor occupancy for
Budda D, van Hasselt JGC, de Lange ECM.
europepmc   +2 more sources

Incidence of Orthostatic Hypotension in Schizophrenic Patients Using Antipsychotics at Sambang Lihum Mental Health Hospital, South Kalimantan

Borneo Journal of Pharmacy, 2021
Schizophrenia is a psychiatric disorder that requires antipsychotics therapy. Antipsychotics cause many side effects, including orthostatic hypotension.
Noor Cahaya, Sandra Putri Wijaya, Khoerul Anwar   +2 more
doaj   +1 more source

Haloperidol for Hypoactive and Hyperactive Delirium in ICU Patients-A Post Hoc Bayesian Analysis of the AID-ICU Trial. [PDF]

Acta Anaesthesiol Scand
ABSTRACT Background Delirium is clinically classified into hypoactive or hyperactive motoric subtypes, which may have different responses to treatment. We assessed heterogeneity in treatment effects according to baseline motoric subtype in the AID‐ICU trial, which randomised adult ICU patients with delirium to haloperidol versus placebo.
Andersen-Ranberg NC, Poulsen LM, Perner A, Hästbacka J, Morgan M, Citerio G, Damby SE, Mortensen CB, Collet MO, Weber SO, Andreasen AS, Bestle M, Uslu B, Pedersen HS, Nielsen LG, Damgaard K, Jensen TB, Sommer T, Dey N, Mathiesen O, Granholm A.   +20 more
europepmc   +2 more sources

Inhibition of drug induced Parkinsonism by chronic supplementation of quercetin in haloperidol-treated wistars

Pakistan Journal of Pharmaceutical Sciences, 2022
Haloperidol is a neuroleptic medication that is used to treat a wide range of neuropsychiatric conditions. It has been shown to produce medicinal effects against hyperactivity, agitation and mania, as well as schizophrenia. Long-term usage of haloperidol
Hamna Rafiq, Muhammad Farhan, Hira Rafi, Sadia Rehman, Maria Arshad, Sarah Shakeel   +5 more
doaj   +1 more source

Differential changes in QTc duration during in-hospital haloperidol use. [PDF]

PLoS ONE, 2011
AIMS: To evaluate changes in QT duration during low-dose haloperidol use, and determine associations between clinical variables and potentially dangerous QT prolongation. METHODS: In a retrospective cohort study in a tertiary university teaching hospital
Marieke T Blom, Abdennasser Bardai, Barbara C van Munster, Mei-Ing Nieuwland, Hendrik de Jong, Daniel A van Hoeijen, Anne M Spanjaart, Anthonius de Boer, Sophia E de Rooij, Hanno L Tan   +9 more
doaj   +1 more source

Effects of cannabidiol on weight and fasting blood sugar with chronic and subchronic haloperidol administration

Discover Mental Health, 2022
Objectives The duration of administration (e.g., subchronic or chronic) of haloperidol may influence its adverse effects. We studied the effects of duration of administration of haloperidol on body weight and fasting blood sugar (FBS).
Jaiyeola Abiola Kajero, Soraya Seedat, Jude U. Ohaeri, Abidemi Akindele, Oluwagbemiga Aina   +4 more
doaj   +1 more source

HALOPERIDOL-INDUCED TORSADES DE POINTES: A CASE REPORT

, 2020
Torsades de pointes (Tdp) is a malignant polymorphic ventricular arrhythmia1 often associated with drugs like haloperidol that prolonged QTc interval2. If enough care is not taken this may lead to sudden death.
SHAZIA FARHEEN QURESHI (8453628)
core   +2 more sources