Results 11 to 20 of about 14,196 (194)

The Burden of Adverse Drug Reactions in Africa in the Context of Pharmacogenetics-Based Clinical Guidelines. [PDF]

open access: yesClin Pharmacol Ther
Genetic variation has a significant impact on patients' response to medicines. Variations in important pharmacogenes have been evaluated in several studies and consequently led to international guidelines from clinical pharmacogenomics consortia. However, there are limited examples of these being implemented across the African continent despite the ...
Scholefield J   +5 more
europepmc   +2 more sources

Serum stress parameters in pigs transported to slaughter under commercial conditions in different seasons

open access: yesVeterinární Medicína, 2007
To determine the influence of slaughter transports carried out under commercial conditions, 162 pigs weighing 98 kg and of both sexes were studied. A total of seven transports were performed in summer and in winter conditions, with durations of 1 h and ...
X. Averos   +4 more
doaj   +1 more source

Drug Hepatotoxicity: Environmental Factors [PDF]

open access: yes, 2017
Drug-induced liver injury presents as various forms of acute and chronic liver disease. There is wide geographic variation in the most commonly implicated agents.
Chalasani, Naga P., Stine, Jonathan G.
core   +1 more source

Efficiency of selection strategies for halothane gene.

open access: yesJournal of Animal Science, 1990
Use of a method to estimate the frequency of the halothane-negative allele in boars is illustrated for different sampling schemes for boar testing programs and for testing within closed breeding populations. This method uses information not only on the individual, but also on all mates and relatives including parents, siblings and offspring.
van Arendonk, J.A.M., Kennedy, B.W.
openaire   +3 more sources

A role for transcriptional repressor methyl-CpG-binding protein 2 and plasticity-related gene serum- and glucocorticoid-inducible kinase 1 in the induction of inflammatory pain states [PDF]

open access: yes, 2007
Activity-dependent changes in neurons of the rat superficial dorsal horn are crucial for the induction and maintenance of neuropathic and inflammatory pain states.
Geranton, SM   +2 more
core   +1 more source

From phenotyping towards breeding strategies: using in vivo indicator traits and genetic markers to improve meat quality in an endangered pig breed

open access: yesAnimal, 2015
In endangered and local pig breeds of small population sizes, production has to focus on alternative niche markets with an emphasis on specific product and meat quality traits to achieve economic competiveness.
A.D.M. Biermann   +5 more
doaj   +1 more source

Congestive heart failure in rats is associated with increased expression and targeting of aquaporin-2 water channel in collecting duct [PDF]

open access: yes, 1997
We tested whether severe congestive heart failure (CHF), a condition associated with excess free-water retention, is accompanied by altered regulation of the vasopressin-regulated water channel, aquaporin-2 (AQP2), in the renal collecting duct.
Andersen, D.   +8 more
core   +2 more sources

Efeito do genótipo halotano e de diferentes sistemas de produção na qualidade da carne suína Effect of the halothane genes and rearing systems on meat quality of pork

open access: yesRevista Brasileira de Zootecnia, 2003
Verificou-se o efeito dos genótipos halotano homozigoto dominante e heterozigoto e dos sistemas de criação confinado sobre piso de cimento, confinado sobre cama de maravalha e ao ar livre sobre a qualidade da carne suína.
Ana Maria Bridi   +4 more
doaj   +1 more source

The response of the tandem pore potassium channel TASK-3 (K2P9.1) to voltage : gating at the cytoplasmic mouth [PDF]

open access: yes, 2009
Although the tandem pore potassium channel TASK-3 is thought to open and shut at its selectivity filter in response to changes of extracellular pH, it is currently unknown whether the channel also shows gating at its inner, cytoplasmic mouth through ...
I. Ashmole   +57 more
core   +1 more source

Strategies for Diagnosis of Diseases in Pigs Using Molecular Markers Review

open access: yesScientific Papers Animal Science and Biotechnologies, 2023
In certain breeds of pigs were identified the porcine stress syndrome (PSS) that determine the appearance of some carcasses inadequate for processing. Because PSS can be triggered by halothane, the gene responsible for the syndrome is often referred to ...
Vasile Băcilă   +4 more
doaj  

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