Results 41 to 50 of about 14,196 (194)

Comments on halothane gene carriers in pigs.

open access: yesAmerican journal of veterinary research, 1993
Biokemi
B, Moesgaard   +4 more
openaire   +3 more sources

Phenotyping malignant hyperthermia susceptibility by measuring halothane‐induced changes in myoplasmic calcium concentration in cultured human skeletal muscle cells [PDF]

open access: yes, 2017
Background. Malignant hyperthermia (MH) is a potentially lethal disease triggered by volatile anaesthetics and succinylcholine in genetically predisposed individuals.
Censier, K.   +5 more
core  

Des marqueurs génomiques au service de la qualité de la viande

open access: yesINRAE Productions Animales, 2015
Le séquençage et l’annotation du génome des principaux animaux producteurs de viande ou de chair, ont permis l’essor des études de génomique au cours de la dernière décennie.
B. PICARD   +8 more
doaj   +1 more source

Malignant Hyperthermia in Sweden: Clinical Presentations and Genetic Findings

open access: yesActa Anaesthesiologica Scandinavica, Volume 70, Issue 6, July 2026.
ABSTRACT Introduction Malignant hyperthermia (MH) is a pharmacogenetic, hypermetabolic and potentially lethal reaction to potent volatile anaesthetics and the muscle relaxant succinylcholine. To improve the understanding of MH, the aim of this retrospective study was to describe the Swedish cohort with respect to clinical manifestations, demographics ...
Anna Hellblom   +2 more
wiley   +1 more source

Actionable Pharmacogenomics and Essential Medicines: An Analysis of WHO and African Lists for Safer and Efficacious Drug Use

open access: yesClinical Pharmacology &Therapeutics, Volume 119, Issue 5, Page 1371-1381, May 2026.
The World Health Organization Model Essential Medicines List and African national essential medicines lists (EMLs) detail drugs intended to be consistently available within national health systems, thereby supporting clinicians and pharmacists in making evidence‐based treatment decisions.
Tinashe A. Mazhindu   +5 more
wiley   +1 more source

Antidepressive and anxiolytic effects of ostruthin, a TREK-1 channel activator [PDF]

open access: yes, 2018
We screened a library of botanical compounds purified from plants of Vietnam for modulators of the activity of a two-pore domain K+ channel, TREK-1, and we identified a hydroxycoumarin-related compound, ostruthin, as an activator of this channel ...
Joseph, Ancy   +3 more
core   +2 more sources

Dossier : Le déterminisme génétique du développement musculaire

open access: yesINRAE Productions Animales, 1996
Les rendements en viande et leur qualité sont étroitement liés au développement musculaire. Les caractéristiques quantitatives et qualitatives des muscles se mettent en place essentiellement dans les phases embryonnaire et néonatale du développement ...
B. FAUCONNEAU
doaj   +1 more source

Molecular dissection of I(A) in cortical pyramidal neurons reveals three distinct components encoded by Kv4.2, Kv4.3, and Kv1.4 alpha-subunits [PDF]

open access: yes, 2010
The rapidly activating and inactivating voltage-gated K(+) (Kv) current, I(A), is broadly expressed in neurons and is a key regulator of action potential repolarization, repetitive firing, backpropagation (into dendrites) of action potentials, and ...
Nerbonne, Jeanne M, Norris, Aaron J
core   +2 more sources

Lactate receptor HCAR1 in neonatal hypoxic–ischemic seizures

open access: yesEpilepsia, Volume 67, Issue 4, Page e46-e53, April 2026.
Abstract Hydroxycarboxylic acid receptor 1 (HCAR1) is a G‐protein‐coupled lactate receptor expressed in the brain and plays a role in neuronal excitability and repair after injury. Hypoxic–ischemic encephalopathy (HIE) is the most common cause of brain injury and seizures in term neonates.
Jennifer Burnsed   +11 more
wiley   +1 more source

Exertional myopathy in Finnish Landrace pigs a survey of the situation and evaluation of different control methods

open access: yesAgricultural and Food Science, 1980
The exertional myopathy situation is surveyed for the top of the breeding pyramid of the Finnish Landrace breed by testing 2,003 pigs and from material on the Norwegian Landrace (86 pigs).
Axel Schulman
doaj  

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