Results 61 to 70 of about 14,196 (194)

Optimising the Use of Cryopreserved Genetic Resources for the Selection and Conservation of Animal Populations

open access: yesJournal of Animal Breeding and Genetics, Volume 143, Issue 1, Page 50-67, January 2026.
ABSTRACT Genetic diversity is essential for the sustainability and adaptability of populations, and is thus a central pillar of the agro‐ecological transition. However, within a population, it is inevitable that some amount of genetic variability is lost, and efforts must be made to limit this as much as possible.
Alicia Jacques   +2 more
wiley   +1 more source

The Concise Guide to PHARMACOLOGY 2025/26: Ion channels

open access: yesBritish Journal of Pharmacology, Volume 182, Issue S1, Page S152-S241, December 2025.
The Concise Guide to Pharmacology 2025/26 marks the seventh edition in this series of biennial publications in the British Journal of Pharmacology. Presented in landscape format, the guide provides a comparative overview of the pharmacology of drug target families. The concise nature of the Concise Guide refers to the style of presentation, being clear,
Stephen P. H. Alexander   +86 more
wiley   +1 more source

Nitrous Oxide: Mechanism of Its Antinociceptive Action [PDF]

open access: yes, 1995
Nitrous oxide (N2O) is an anesthetic gas known to produce an analgesic effect at sub-anesthetic concentrations. This analgesic property of N2O can be clinically exploited in a broad range of conditions where pain relief is indicated.
Quock, Raymond M., Vaughn, Linda K.
core   +1 more source

Loss of neurons from laminas I-III of the spinal dorsal horn is not required for development of tactile allodynia in the spared nerve injury model of neuropathic pain [PDF]

open access: yes, 2005
It has been proposed that death of inhibitory interneurons in the dorsal horn contributes to the neuropathic pain that follows partial nerve injury. In this study, we have used two approaches to test whether there is neuronal death in the dorsal horn in ...
Arham, A.Z.   +3 more
core   +2 more sources

Elevated cortisol concentration in preterm sheep fetuses impacts heart development

open access: yesExperimental Physiology, Volume 110, Issue 12, Page 1928-1947, December 1, 2025.
Abstract The prepartum rise in cortisol promotes cardiac development and maturation. Here, we investigated the impact of elevated circulating cortisol during mid‐late gestation on cardiac growth and metabolism in fetal sheep. Saline or cortisol (2–3 mg in 4.4 mL/24 h) was infused into the fetal jugular vein from 109 to 116 days gestation (dG, term ...
Reza Amanollahi   +9 more
wiley   +1 more source

Frequency of Favorable Alleles for Meat Quality, Litter Size, Adaptation, and Growth Traits in Closed Nucleus Population of Philippine Native Swine (Sus philippensis var. markaduke)

open access: yesCluj Veterinary Journal
The Philippine native swine (PNS) are heritage domestic animal genetic resources for food security and geo-cultural uses.  Among the PNS, the markaduke is known for the "best lechon" (roast whole pork) and comminuted pork products, moderate litter size (
Arnolfo Monleon
doaj   +1 more source

Global anaesthesia practice using inguinal hernia surgery as a tracer condition: a secondary analysis of an international prospective cohort study

open access: yesAnaesthesia, Volume 80, Issue 11, Page 1343-1351, November 2025.
Summary Introduction Restoration of surgical capacity is essential to post‐COVID‐19 recovery. This study explored the use and safety of anaesthesia options for inguinal hernia surgery, a common tracer condition, to describe current global practice and highlight opportunities to build the capacity of health systems.
NIHR Global Health Research Group on Environmentally Sustainable Hospitals in Low‐ and Middle‐income Countries   +5007 more
wiley   +1 more source

Bidirectional Relationship Between Anaesthetic Drugs and Metabolic Syndrome: Clinical Effects and Mechanisms

open access: yesJournal of Cellular and Molecular Medicine, Volume 29, Issue 20, October 2025.
ABSTRACT Metabolic syndrome (MS) is a multifaceted condition characterised by insulin resistance, dyslipidemia, central obesity and hypertension, significantly elevating the risks of cardiovascular diseases and type 2 diabetes. This review aims to elucidate the bidirectional interplay between anaesthetic agents and MS, highlighting the mutual influence
Yuying Huang   +6 more
wiley   +1 more source

ADAMTS -1 and -4 are up-regulated following transient middle cerebral artery occlusion in the rat and their expression is modulated by TNF in cultured astrocytes [PDF]

open access: yes, 2006
ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) enzymes are a recently described group of metalloproteinases. The substrates degraded by ADAMTS-1, -4 and -5 suggests that they play a role in turnover of extracellular matrix in the
A.K. Cross   +52 more
core   +1 more source

Goα Regulates Volatile Anesthetic Action in Caenorhabditis elegans [PDF]

open access: yes, 2001
To identify genes controlling volatile anesthetic (VA) action, we have screened through existing Caenorhabditis elegans mutants and found that strains with a reduction in Go signaling are VA resistant.
Crowder, C. Michael   +5 more
core  

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