Results 121 to 130 of about 399,690 (387)
Multi‐omics analysis revealed that FOS supplementation increased the abundance of Phascolarctobacterium, GCA‐900066575, Shuttleworthia, Olsenella, Eubacterium_hallii_group while decreasing Alistipes. It also influenced the metabolism of S‐lactoylglutathione, p‐cresol glucuronate, 2‐phenylethanol glucuronide, propionic acid, dulcitol, and inhibited the ...
Dan Song+11 more
wiley +1 more source
A Setup for Automatic Raman Measurements in High‐Throughput Experimentation
Record Raman spectra in High‐Throughput Bioprocess Development. Measure eight samples of 50μL $50\,\mathrm{\mu L}$ fully automated. ABSTRACT High‐throughput (HT) experimentation is transforming biotechnology by enabling systematic exploration of complex multi‐dimensional experimental conditions.
Christoph Lange+8 more
wiley +1 more source
Induction of chromosome shattering by ultraviolet light and caffeine: The influence of different distributions of photolesions [PDF]
Cells of synchonized and of asynchronously growing cultures of a V79 Chinese hamster line were microirradiated with a low poweer laser-UV-microbeam of wavelength 257 nm.
Barranco+42 more
core +1 more source
Host Cell Protein Clinical Safety Risk Assessment—An Updated Industry Review
ABSTRACT Host cell proteins (HCP) are process‐related impurities that can co‐purify with therapeutic proteins. Some HCP impurities potentially can have an impact on patient safety (immunogenicity or toxicity), efficacy, and/or product quality. It is important to reduce the levels of HCP impurities with a well‐controlled manufacturing process and to ...
Lisette Coye+19 more
wiley +1 more source
Analysis of chromosome positions in the interphase nucleus of Chinese hamster cells by laser-UV-microirradiation experiments [PDF]
Unsynchronized cells of an essentially diploid strain of female Chinese hamster cells derived from lung tissue (CHL) were laser-UV-microirradiated (=257 nm) in the nucleus either at its central part or at its periphery.
B Dutrillaux+38 more
core +1 more source
ABSTRACT Single‐cell isolation is an essential step in many biomedical workflows, including genetic analyses and drug‐based assays. It is commonly attempted through limiting dilution into microtiter wells. However, dark optical edge effects at the well periphery make it difficult to confirm which wells contain just one cell.
Joseph A. E. Morgan+3 more
wiley +1 more source
AutoML‐Driven Soft Sensors for Real‐Time Monitoring of Amino Acids in Mammalian Perfusion Cultures
ABSTRACT Mammalian perfusion culture offers high productivity for complex biologics but presents operational challenges in maintaining process stability. Real‐time monitoring is essential to address such challenges while traditional analytical methods often fall short due to several limitations such as detection sensitivity and spectral overlap ...
Sun‐Jong Kim+4 more
wiley +1 more source
Kongratanapasert T, Kongsomros S, Arya N, et al. J Exp Pharmacol. 2023;15:13–26. Page 19, line two, the text “510.25 ± 329.37 and 2015.74 ± 708.53 μg/g” should read “510.25 ± 329.37 and 2015.74 ...
Kongratanapasert T+18 more
doaj
Leishmania-activated C-kinase antigen (LACK) is a highly conserved protein among Leishmania species and is considered a viable vaccine candidate for human leishmaniasis.
Laura Fernández+8 more
doaj +1 more source
THE PROBLEM OF THE SIGNIFICANCE OF THE INCLUSION BODIES FOUND IN THE SALIVARY GLANDS OF INFANTS, AND THE OCCURRENCE OF INCLUSION BODIES IN THE SUBMAXILLARY GLANDS OF HAMSTERS, WHITE MICE, AND WILD RATS (PEIPING) [PDF]
Ann G. Kuttner, Shao-Hsun Wang
openalex +1 more source