Results 151 to 160 of about 399,690 (387)
Proton first: rationalizing a proton transfer in a protein‐fragment complex
ChemMedChem, Accepted Article.We present a combination of experimental and theoretical approaches to decipher the molecular recognition event of benzoic acid complexed with Protein Kinase A. The publicly known crystal structure suggests the protonated form of benzoic acid to be complexed with Protein Kinase A.
Helge Vatheuer +6 more
wiley +1 more source
ChemMedChem, EarlyView.There is no suitable radioligand for positron emission tomography imaging of CB2R overexpression for routine clinical usage. Herein, the synthesis, characterization, binding affinity, and docking studies of carborane‐based halo‐substituted naphthyridinone derivatives as CB2R ligands are presented.
Lea Ueberham +4 more
wiley +1 more source
Synthetic LXR agonists increase LDL in CETP species
Journal of Lipid Research, 2005 Liver X receptor (LXR) nuclear receptors regulate the expression of genes involved in whole body cholesterol trafficking, including absorption, excretion, catabolism, and cellular efflux, and possess both anti-inflammatory and antidiabetic actions ...
Pieter H.E. Groot +21 more
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Neutralizing gut-derived lipopolysaccharide as a novel therapeutic strategy for severe leptospirosis
eLifeLeptospirosis is an emerging infectious disease caused by pathogenic Leptospira spp. Humans and some mammals can develop severe forms of leptospirosis accompanied by a dysregulated inflammatory response, which often results in death.
Xufeng Xie +5 more
doaj +1 more source
Hamster leukemia virus: lack of endogenous DNA synthesis and unique structure of its DNA polymerase [PDF]
, 1974 Infectious hamster leukemia virus (HaLV) contains a DNA polymerase different from those of murine and avian viruses. No endogenous reaction directed by the 60 to 70S RNA of HaLV could be demonstrated in detergenttreated HaLV virions, nor could the ...
Baltimore, David +3 more
core
STUDIES OF RABIES STREET VIRUS IN THE SYRIAN HAMSTER [PDF]
, 1951 Reginald L. Reagan +3 more
openalex +1 more source
ChemMedChem, EarlyView.Several derivatives incorporating five‐membered aromatic rings are described in this review as bile acid receptor modulators, particularly targeting the farnesoid X receptor and the G protein‐coupled bile acid receptor 1. This review provides a comprehensive analysis of patents and literature that is useful to support researchers in the design of new ...
Claudia Finamore +5 more
wiley +1 more source
Journal of Lipid Research, 1966 Sacs and segments of everted hamster gut were incubated in vitro in solutions of mixed micelles (containing taurodeoxycholate, monoolein, and linolenic acid) for various periods and at different temperatures. The appearance of electron micrographs of the
Elliott W. Strauss
doaj