ABSTRACT Current preclinical models for cervical dysplasia rely on animal systems that poorly mimic human anatomy. To address this and align with emerging initiatives to reduce animal experimentation, we developed a human‐sized, 3D in vitro model of high‐grade cervical dysplasia.
Gatha Adhikari +3 more
wiley +1 more source
Correction to "Metabolomics of the Protective Effect of <i>Ampelopsis grossedentata</i> and Its Major Active Compound Dihydromyricetin on the Liver of High-Fat Diet Hamster". [PDF]
europepmc +1 more source
A community reconstruction of Chinese hamster metabolism and structural systems biology elucidate metabolic rewiring in lactate-free CHO cells. [PDF]
Di Giusto P +40 more
europepmc +1 more source
Abstract BACKGROUND Selecting an optimal chromatography resin during biopharmaceutical downstream process development is a great challenge. This is especially the case for recombinant subunit vaccines, where product properties vary greatly and recovery often involves cell lysis, which yields a complex mixture of different host cell materials. Host cell
Tim Neijenhuis +4 more
wiley +1 more source
Adapted Live SARS-CoV-2 Vaccine Elicits Rapid Mucosal Immunity, Protects From Disease, and Reduces Shedding of XBB.1.5. [PDF]
Kochmann J +13 more
europepmc +1 more source
Exploring supported ionic liquids for IgY antibody purification
Abstract BACKGROUND Immunoglobulin Y (IgY), a scalable alternative to mammalian antibodies, typically found in hen's egg yolk, has gained attraction in diagnostic and therapeutic applications. However, its purification from egg yolk remains challenging due to the complex matrix and limitations of conventional techniques. Supported Ionic Liquids (SILs),
Amanda RP Silva +4 more
wiley +1 more source
Efficient production of fully active, SARS-CoV-2-priming, wildtype TMPRSS2 ectodomain via co-expression of HAI-2 allows for both auto- and cross-activation mechanisms. [PDF]
Végh B +6 more
europepmc +1 more source
What Is Your Diagnosis? Submandibular Mass in a Dog
Veterinary Clinical Pathology, EarlyView.
Whitney K. Chandler +3 more
wiley +1 more source
Current Evidence of the Effect of Breastfeeding on Ear Molding Outcomes: A Scoping Review
ABSTRACT Objective To provide an overview on auricular molding and to investigate whether breastfeeding is associated with greater cartilage malleability or improved perinatal auricular molding outcomes. Data Sources Embase, MEDLINE, and CENTRAL databases.
Harry Chiang +5 more
wiley +1 more source
Monitoring reproduction in cryptic small mammals; using body temperature to identify parturition in an endangered rodent. [PDF]
Gérard T +4 more
europepmc +1 more source

