Results 191 to 200 of about 115,928 (265)

Beyond Starch: Towards a Scalable Potato Platform for Molecular Farming

Plant Biotechnology Journal, Volume 24, Issue 7, Page 4619-4639, July 2026.
Re‐engineering potato as a biosafe and host‐optimised platform for plant molecular farming by integrating intrinsic biological traits with targeted engineering strategies. ABSTRACT Thirty‐five years after the first recombinant protein was produced in potato and 30 years after clinical trials of edible vaccines from its tubers, the crop is being ...
Izabela Anna Chincinska, Dorota Sołtys‐Kalina, Audrey Y.‐H. Teh   +2 more
wiley   +1 more source

Daily torpor in summer- and winter-acclimated hamsters: are thermal biology and balancing energy budgets under a different seasonal physiological control? [PDF]

J Comp Physiol B
Geiser F, Bieber C, Ruf T.
europepmc   +1 more source

Quantitative Microbial Risk Assessment of Human H5N1 Infection From Consumption of Fluid Cow's Milk

Risk Analysis, Volume 46, Issue 7, July 2026.
ABSTRACT The spillover of H5N1 clade 2.3.4.4b into dairy cattle has raised concerns over the safety of fluid milk. While no foodborne infection has been reported in humans, this strain has infected at least 70 people, and milk from infected cows is known to be infected by ingestion of multiple other species.
Katherine J. Koebel, Ece Bulut, Samuel D. Alcaine, Aljoša Trmčić, Mohammed Nooruzzaman, Lina M. Covaleda, Diego G. Diel, Renata Ivanek   +7 more
wiley   +1 more source

Retatrutide Shows Multiple Metabolic Benefits in Diet-Induced Obese MASH Mouse and Hamster Models. [PDF]

Obesity (Silver Spring)
Briand F, Le Cudennec C, Grasset E, Breyner N, Bigot C, Dillard P, Sulpice T.   +6 more
europepmc   +1 more source

Efficacy of the nucleoside analog 4'-Fluorouridine against Nipah virus in the Syrian hamster model. [PDF]

PLoS Pathog
Escaffre O, Pearson ML, Juelich TL, Smith JK, Zhang L, Lieber CM, Vyshenska D, Ikegami T, Haas GD, Krueger RE, Sticher Z, Kolykhalov AA, Natchus MG, Painter GR, Johnson KN, Greninger AL, Cox RM, Plemper RK, Lee B, Freiberg AN.   +19 more
europepmc   +1 more source

Transient Transfection of Rolling‐Circle Amplified DNA in Biomanufacturing‐Relevant Mammalian Cell Lines: A Comparison of Transfection Conditions for Optimal Protein Expression

Biotechnology and Applied Biochemistry, Volume 73, Issue 3, Page 1358-1367, June 2026.
ABSTRACT Rolling‐circle amplification (RCA) is a completely synthetic and rapid mechanism for scaling‐up bulk DNA that eliminates requirements for large‐scale bacterial fermentation. Several reports have described the surprising ability of large unprocessed (hyperbranched) rolling circle‐amplified DNA (RCA DNA) to effectively transfect cultured cells ...
Evelina Loghin, Erik Kvam, Lisa Lowery, Nathan Hudson, Jenny Keen, Brian Davis, Roger B. Dodd, Christine Surrette, John Nelson   +8 more
wiley   +1 more source

Targeting ApoA5-Associated Hypertriglyceridemia to Ameliorate Acute Pancreatitis: Insights From a Knockout Hamster Model. [PDF]

MedComm (2020)
Shi S, Lu K, Tao Y, Zhang Y, Zhang L, Liu G, Huang W, Wang Y, Xian X.   +8 more
europepmc   +1 more source

High‐Yield Production and Cost‐Effective Purification of an Alkali‐Resistant Hexameric Protein A Variant for Antibody Affinity Chromatography

Biotechnology Journal, Volume 21, Issue 6, June 2026.
Graphical Abstract and Lay Summary We present a scalable method for producing the antibody‐binding ligand Z6AlkC, a six‐repeat, alkali‐resistant Protein A–derived Z domain with a terminal cysteine. The ligand was produced at high yield via extracellular secretion in bioreactors and subsequently purified by high‐productivity ultradiafiltration with low ...
Carolina Mota Natal, Claudia Lacombe, Alexander Zollner, Catarina Domingos, José Mendes, André Nascimento, Ana Margarida Gonçalves Carvalho Dias, Arménio Jorge Moura Barbosa, Cristina Peixoto, Birgit Wiltschi, Alois Jungbauer, Ana Cecília Afonso Roque   +11 more
wiley   +1 more source

TMPRSS2 is dispensable for lethal SARS-CoV-2 BA.5 infection in humanized hACE2 golden hamsters. [PDF]

Eur J Med Res
Wang B, Zhang J, Li Y, Wang H, Dong M, Chen Q, Shi A, Zhang A, Zeng W, Wang X, Li J.   +10 more
europepmc   +1 more source