Results 201 to 210 of about 254,338 (311)

The Recycling Endosomal (Na+, K+)/H+ Exchanger NHE6/SLC9A6 Facilitates Signal Transduction by Shuttling Cyclin‐Dependent Kinase 5 to the Plasma Membrane

open access: yesActa Physiologica, Volume 242, Issue 6, June 2026.
ABSTRACT Aim The alkali cation/proton exchanger NHE6/SLC9A6 regulates luminal pH homeostasis and trafficking of recycling endosomes in most tissues, especially neurons. Loss‐of‐function mutations in NHE6 cause Christianson Syndrome, an X‐linked neurodevelopmental and neurodegenerative disorder; however, the underlying molecular and cellular mechanisms ...
Rebecca Flessner   +6 more
wiley   +1 more source

∆FOSB in the Nucleus Accumbens Core Is Required for Increased Anxiety, but Not Decreased Social Motivation, Following Estrogen Withdrawal in Female Mice

open access: yesGenes, Brain and Behavior, Volume 25, Issue 3, June 2026.
In female mice, estrogen withdrawal following a hormone‐simulated pseudopregnancy is associated with increased levels of ∆FOSB in the Nucleus Accumbens Core and increased anxiety behaviors. However, using viral‐mediated expression of ∆JUND to decrease ∆FOSB‐mediated transcription in the Nucleus Accumbens Core prevents the increase in anxiety following ...
Willow Clayton   +9 more
wiley   +1 more source

Efficacy of the nucleoside analog 4'-Fluorouridine against Nipah virus in the Syrian hamster model. [PDF]

open access: yesPLoS Pathog
Escaffre O   +19 more
europepmc   +1 more source

Production of the High Value Pharmaceutical Target, Human Granulocyte‐Colony Stimulating Factor, in Nicotiana benthamiana Is Improved by Co‐Expression of the Transcriptional Regulator of the Unfolded Protein Response, bZIP60

open access: yes
Plant Biotechnology Journal, EarlyView.
Nazgul Wagner   +7 more
wiley   +1 more source

Dehnel's Phenomenon in Mammals

open access: yesMammal Review, Volume 56, Issue 2, June 2026.
Some small mammals, which remain active year‐round, undergo reversible reductions in body size, braincase height, and the mass of internal organs, including the brain, from summer to winter. It is called Dehnel's phenomenon. In this review, we summarise knowledge of the mechanisms, adaptive value, and genetic basis of the phenomenon, and show how new ...
Jan R. E. Taylor   +2 more
wiley   +1 more source

Understanding the Phenotypic Heterogeneity Within the Sporadic Creutzfeldt–Jakob Disease MV1 Subtype

open access: yesNeuropathology and Applied Neurobiology, Volume 52, Issue 3, June 2026.
We present the clinical, pathological and prion biophysical features of three atypical cases of the MV1 subtype of sporadic Creutzfeldt–Jakob disease (sCJD). We propose that these heterozygous cases exist on a spectrum ranging from MM1‐like to VV1‐like phenotypes and recommend that subtyping be performed at pH 6.9 to avoid missing atypical or mixed ...
Satish K. Nemani   +6 more
wiley   +1 more source

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