Results 211 to 220 of about 306,860 (343)

Developing downstream processes for the purification of recombinant proteins and small molecules from Nicotiana benthamiana biomass

open access: yesPlant Biotechnology Journal, EarlyView.
Summary Nicotiana benthamiana (Australian tobacco) has become a major host for plant‐based recombinant protein production, especially using transient expression. Once a candidate protein has been designed and produced in a suitable variety (e.g. facilitated humanized glycosylation) under reproducible conditions (e.g.
J. F. Buyel
wiley   +1 more source

CRISPR/Cas9‐Mediated Knockouts of the ALG3 and GNTI in N. benthamiana and Their Application to Pharmaceutical Production

open access: yesPlant Biotechnology Journal, EarlyView.
ABSTRACT N‐Glycosylation critically influences the efficacy, safety and pharmacokinetic properties of biopharmaceuticals. Plant expression platforms offer multiple advantages for the production of N‐glycosylated proteins, but their use is impeded by the presence of plant‐specific N‐glycan epitopes, which raise concerns of possible immunogenicity to ...
Dolgormaa Bataa   +7 more
wiley   +1 more source

Human Polyomavirus BK Genome Analysis in BKPyV Induced Rodent Cell Lines. [PDF]

open access: yesMicrobiologyopen
Shioda S   +6 more
europepmc   +1 more source

A synthesis view of counterfactuals

open access: yesPhilosophy and Phenomenological Research, EarlyView.
Abstract There are two prominent views of counterfactuals in the literature—variably strict conditional accounts developed by Stalnaker 1968 and D. K. Lewis 1973, and strict conditional accounts defended by von Fintel 2001, Gillies 2007, and others. Unfortunately, both views face serious challenges. This paper argues that traditional strict conditional
Sarah Moss
wiley   +1 more source

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