Results 91 to 100 of about 8,919,752 (327)
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Canine Trainers in Russian National Guard: Professional and Personal Qualities during Training
СибСкриптProfessional qualities and personality traits affect the efficiency of canine team in the Russian National Guard during routine service and military operations.
Tatyana P. Skripkina, Elena A. Kusakina
doaj +1 more source
Piloted-simulation study of effects of vortex flaps on low-speed handling qualities of a Delta-wing airplane [PDF]
A piloted-simulation study was conducted to investigate the effects of vortex flaps on low-speed handling qualities of a delta-wing airplane. The simulation math model was developed from wind tunnel tests of a 0.15 scale model of the F-106B airplane ...
Brandon, Jay M. +2 more
core +1 more source
Molecular Oncology, EarlyView.The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source
AnimalsThe human–animal relationship is crucial for animal welfare. Gentle handling enhances pigs’ comfort while rough handling causes fear and stress. This study examined how different human–animal relationship qualities affect the behavior and heart rate ...
Javiera Calderón-Amor +9 more
doaj +1 more source
An in-flight simulation of lateral control nonlinearities [PDF]
An in-flight simulation program was conducted to explore, in a generalized way, the influence of spoiler-type roll-control nonlinearities on handling qualities.
Ellis, D. R., Tilak, N. W.
core +1 more source
A design procedure for the handling qualities optimization of the X-29A aircraft [PDF]
A design technique for handling qualities improvement was developed for the X-29A aircraft. As with any new aircraft, the X-29A control law designers were presented with a relatively high degree of uncertainty in their mathematical models.
Bosworth, John T., Cox, Timothy H.
core +2 more sources
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Basic principals of the tiltrotors flight control system architecture and algorithms
Научный вестник МГТУ ГАThis study describes the main structure and algorithm development principles of flight control systems for tiltrotor aircraft using the example of rotary-wing aircraft V-22 Osprey and AW609.
M. I. Myasnikov, I. R. Ilyin
doaj +1 more source
Lateral ride quality of the B-1 aircraft subjected to a reduction of lateral static stability [PDF]
A method to evaluate the lateral ride quality of a B-1 aircraft subjected to a reduction in lateral static stability is developed. Ride quality is then found for three different relaxed static stability configurations which are augmented by yaw rate ...
Hinsdale, A. J.
core +1 more source