Results 41 to 50 of about 8,919,752 (327)
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
By dawn or dusk—how circadian timing rewrites bacterial infection outcomes
FEBS Letters, EarlyView.The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo +2 more
wiley +1 more source
Hematopoietic (stem) cells—The elixir of life?
FEBS Letters, EarlyView.The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo +4 more
wiley +1 more source
Study of The Flying and Handling Qualities of a Glider-Type Aircraft for Instruction Purposes
Ciencia y Poder Aéreo, 2019 The goal of this paper is to conduct a study on the flying and usability attributes of a glider-type aircraft used for instruction. For the development of this project, we propose a dynamic model where we introduce small disturbances to calculate the ...
Yeinson Alfonso Castellanos Sanabria +1 more
doaj +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Examining the stability derivatives of a compound helicopter [PDF]
, 2016 Some helicopter manufacturers are exploring the compound helicopter design as it could potentially satisfy the new emerging requirements placed on the next generation of rotorcraft.
Ferguson, Kevin, Thomson, Douglas
core +1 more source
Molecular bases of circadian magnesium rhythms across eukaryotes
FEBS Letters, EarlyView.Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley +1 more source
Building Credible VTOL Flight Models for Handling Quality Certification by Simulation
AerospaceCertifying novel VTOL aircraft handling qualities (HQs) may be challenging, relying on costly and high-risk flight testing. This paper presents a methodology to establish the credibility of flight simulation models for certification by simulation, aiming
Lorenzo Favaro +2 more
doaj +1 more source
Preparation and Characterization of Al/HTPB Composite for High Energetic Materials
Nanomaterials, 2020 Nanosized Al (nAl) powders offer increased reactivity than the conventional micron-sized counterpart, thanks to their reduced size and increased specific surface area.
Alexander Vorozhtsov +5 more
doaj +1 more source