Results 81 to 90 of about 8,919,752 (327)

Tumor and germline testing with next generation sequencing in epithelial ovarian cancer: a prospective paired comparison using an 18‐gene panel

open access: yesMolecular Oncology, EarlyView.
Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard   +12 more
wiley   +1 more source

Handling qualities aspects of NASA YF-12 flight experience [PDF]

open access: yes
The handling qualities of the YF-12 airplane as observed during NASA research flights over the past five years were reviewed. Aircraft behavior during takeoff, acceleration, climb, cruise, descent, and landing are discussed. Pilot comments on the various
Berry, D. T.   +2 more
core   +1 more source

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

open access: yesMolecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad   +12 more
wiley   +1 more source

Sliding Mode Implementation of an Attitude Command Flight Control System for a Helicopter in Hover

open access: yesActa Polytechnica, 2005
This paper presents an investigation into the design of a flight control system, using a decoupled non-linear sliding mode control structure, designed using a linearised, 9th order representation of the dynamics of a PUMA helicopter in hover.
D. J. McGeoch   +2 more
doaj  

Handling qualities requirements for control configured vehicles [PDF]

open access: yes
The potential effects of fly by wire and control configured vehicle concepts on flying qualities are considered. Failure mode probabilities and consequences, controllability, and dynamics of highly augmented aircraft are among the factors discussed in ...
George, F. L., Woodcock, R. J.
core   +1 more source

Investigation of a Compound Helicopter Flying the Depart and Abort Mission Task Element [PDF]

open access: yes, 2017
The next generation of rotorcraft will have to satisfy the appropriate handling qualities requirements before entering service. Many of these vehicles will operate at significantly greater speeds than the conventional helicopter and will therefore have
Anderson, Dave   +2 more
core  

Strength through diversity: how cancers thrive when clones cooperate

open access: yesMolecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken   +3 more
wiley   +1 more source

Ride quality sensitivity to SAS control law and to handling quality variations [PDF]

open access: yes
The RQ trends which large flexible aircraft exhibit under various parameterizations of control laws and handling qualities are discussed. A summary of the assumptions and solution technique, a control law parameterization review, a discussion of ride ...
Roberts, P. A.   +2 more
core   +1 more source

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

open access: yesMolecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié   +13 more
wiley   +1 more source

Handling Qualities Assessment and Discussion for Helicopter with Slung Load Systems Utilizing Various Sling Configurations

open access: yesAerospace
Sling configurations significantly influence the coupled dynamics of the helicopter with slung load system (HSLS), resulting in alterations to handling qualities (HQs) that remain inadequately understood.
Luofeng Wang, Renliang Chen
doaj   +1 more source

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