Results 51 to 60 of about 11,099 (172)

Hantavirus-infection confers resistance to cytotoxic lymphocyte-mediated apoptosis. [PDF]

open access: yesPLoS Pathogens, 2013
Hantaviruses cause hemorrhagic fever with renal syndrome (HFRS) and hantavirus cardio-pulmonary syndrome (HCPS; also called hantavirus pulmonary syndrome (HPS)), both human diseases with high case-fatality rates.
Shawon Gupta   +7 more
doaj   +1 more source

Clinical Value the Neutrophil CD64 Index in Predicting the Severity of Hemorrhagic Fever With Renal Syndrome

open access: yesImmunity, Inflammation and Disease, Volume 14, Issue 4, April 2026.
(1) The expression of neutrophil CD64 index (nCD64 index) was generally elevated in hemorrhagic fever with renal syndrome patients and demonstrated a positive correlation with white blood cell (WBC), neutrophil, lymphocyte, monocyte, and procalcitonin (PCT), as well as a negative correlation with platelet.
Chuantao Ye   +11 more
wiley   +1 more source

Community Assembly Reveals How Environmental Controls Over Rodent Competition Drive Deer Mouse Density and Hantavirus Infection

open access: yesEcology Letters, Volume 29, Issue 4, April 2026.
We examined how community assembly processes shape Sin Nombre hantavirus (SNV) dynamics in rodent communities across the southwestern United States. Environmental factors structured community composition, which regulated deer mouse abundance and SNV infection, rather than diversity alone.
Angela D. Luis, Dean E. Pearson
wiley   +1 more source

Structure of the Hantavirus Nucleoprotein Provides Insights into the Mechanism of RNA Encapsidation

open access: yesCell Reports, 2016
Hantaviruses are etiological agents of life-threatening hemorrhagic fever with renal syndrome and hantavirus cardiopulmonary syndrome. The nucleoprotein (N) of hantavirus is essential for viral transcription and replication, thus representing an ...
Daniel Olal, Oliver Daumke
doaj   +1 more source

Global Interdependence, Just Vaccine Allocation, and Compensatory Justice: A New Model

open access: yesDeveloping World Bioethics, Volume 26, Issue 1, Page 17-22, March 2026.
ABSTRACT During the COVID‐19 pandemic, numerous models were offered for how scarce vaccine resources should be distributed. Proposed vaccine distribution models generally were divided between nationalist models, which give preference to nationals, and cosmopolitan models, which ignore national boundaries.
Kalen J. Fredette
wiley   +1 more source

Deletions in Genes Participating in Innate Immune Response Modify the Clinical Course of Andes Orthohantavirus Infection

open access: yesViruses, 2019
Andes orthohantavirus (ANDV) is an important human pathogen causing hantavirus cardiopulmonary syndrome (HCPS) with a fatality rate of 30% in Chile. Around 60% of all cases have a severe clinical course, while the others have a mild clinical course.
Grazielle Esteves Ribeiro   +7 more
doaj   +1 more source

New Insights Into the Evolution of Immune Adaptors in Murid Rodents

open access: yesEcology and Evolution, Volume 16, Issue 1, January 2026.
TIR domain‐containing adaptors were evolved under purifying selection in murine. Positively selected sites were identified in Mal and Myd88 genes. Reduced genetic diversity of each adaptor gene was observed in two rat populations. Shared polymorphisms were common phenomena in rat adaptors.
Qianqian Su, Zhenhua She, Yi Chen
wiley   +1 more source

Hemorrhagic fever with renal syndrome and coexisting hantavirus pulmonary syndrome

open access: yesKidney Research and Clinical Practice, 2012
Hemorrhagic fever with renal syndrome (HFRS) is an acute viral disease with fever, hemorrhage and renal failure caused by hantavirus infection. Hantavirus induces HFRS or hantavirus pulmonary syndrome (HPS).
Young Min Hong   +6 more
doaj   +1 more source

Leveraging Long‐Term Ecological Research Initiatives Into the One Health Synthesis

open access: yesEcology and Evolution, Volume 16, Issue 1, January 2026.
We address important ecological and evolutionary considerations for advancing a One Health perspective by drawing attention to faunal and ecosystem changes occurring through the Great Plains of North America that have strong implications for future risk of emerging pathogens including zoonoses.
Andrew G. Hope   +2 more
wiley   +1 more source

An Improved Enzyme-Linked Focus Formation Assay Revealed Baloxavir Acid as a Potential Antiviral Therapeutic Against Hantavirus Infection

open access: yesFrontiers in Pharmacology, 2019
Hantaviruses, etiologic pathogens responsible for two severe human diseases, exist in areas ranging from Eurasia to America and remain global public health concerns. Conventionally, plaque formation assays have been used for hantavirus titering. However,
Chuantao Ye   +14 more
doaj   +1 more source

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