New Insights Into the Evolution of Immune Adaptors in Murid Rodents
Ecology and Evolution, Volume 16, Issue 1, January 2026.TIR domain‐containing adaptors were evolved under purifying selection in murine. Positively selected sites were identified in Mal and Myd88 genes. Reduced genetic diversity of each adaptor gene was observed in two rat populations. Shared polymorphisms were common phenomena in rat adaptors.
Qianqian Su, Zhenhua She, Yi Chen
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Hantavirus in rodents in the United States: Temporal and spatial trends and report of new hosts
EcosphereIn North America, the rodent‐borne hantavirus pulmonary syndrome is predominantly caused by the Sin Nombre virus, typically associated with the deer mouse Peromyscus maniculatus.
Francisca Astorga +4 more
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Memorias do Instituto Oswaldo Cruz, 2004 We report a nested reverse transcription-polymerase chain reaction (RT-PCR) assay for hantavirus using primers selected to match high homology regions of hantavirus genomes detected from the whole blood of hantavirus cardiopulmonary syndrome (HCPS ...
Marcos Lázaro Moreli +2 more
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A Theoretical Framework for the Analysis of the West Nile Virus Epidemic
, 2004 We present a model for the growth of West Nile virus in mosquito and bird populations based on observations of the initial epidemic in the U.S. Increase of bird mortality as a result of infection, which is a feature of the epidemic, is found to yield an ...
Abramson +15 more
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Leveraging Long‐Term Ecological Research Initiatives Into the One Health Synthesis
Ecology and Evolution, Volume 16, Issue 1, January 2026.We address important ecological and evolutionary considerations for advancing a One Health perspective by drawing attention to faunal and ecosystem changes occurring through the Great Plains of North America that have strong implications for future risk of emerging pathogens including zoonoses.
Andrew G. Hope +2 more
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The hanta hunting study: Underdiagnosis of puumala hantavirus infections in symptomatic non-travelling leptospirosis-suspected patients in the Netherlands, in 2010 and April to November 2011 [PDF]
, 2014 Leptospirosis and haemorrhagic fever with renal syndrome (HFRS) are hard to distinguish clinically since these two important rodent-borne zoonoses share hallmark symptoms such as renal failure and haemorrhage.
Goeijenbier, M. (Marco) +11 more
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Strategic Preparedness of Broad‐Spectrum Antivirals for Rapid Response Towards Next Pandemics
Small Science, Volume 6, Issue 1, January 2026.Nanoengineered broad‐spectrum antivirals (BSAs) represent a transformative approach to pandemic preparedness. Unlike virus‐specific drugs requiring separate development, BSAs act across multiple viral families through nanoengineering strategies that enhance solubility, bioavailability, and host‐targeted activity.
Sanoj Rejinold N +2 more
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Dendritic Cells (DCs) as "Fire Accelerants" of Hantaviral Pathogenesis [PDF]
, 2019 Hantaviruses are widespread zoonotic pathogens found around the globe. Depending on their geographical location, hantaviruses can cause two human syndromes, haemorrhagic fever with renal syndrome (HFRS) or hantavirus pulmonary syndrome (HPS).
Raftery, Martin J., Schönrich, Günther
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Hantavirus-infection confers resistance to cytotoxic lymphocyte-mediated apoptosis. [PDF]
PLoS Pathogens, 2013 Hantaviruses cause hemorrhagic fever with renal syndrome (HFRS) and hantavirus cardio-pulmonary syndrome (HCPS; also called hantavirus pulmonary syndrome (HPS)), both human diseases with high case-fatality rates.
Shawon Gupta +7 more
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Advances in Microbial Diagnostics: Machine Learning and Nanotechnology for Zoonotic Disease Control
WIREs Nanomedicine and Nanobiotechnology, Volume 18, Issue 1, January/February 2026.This review highlights how integrating machine learning with nanotechnology enables enhanced diagnostics, personalized treatments, and the prediction of outbreaks for zoonotic diseases, offering a unified framework to advance global health. ABSTRACT Zoonotic diseases pose significant global health threats, with microbial pathogens, including bacteria ...
Narges Lotfalizadeh +8 more
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