Results 71 to 80 of about 5,678 (196)

Combining ability of doubled haploids in Coffea canephora P. [PDF]

open access: yes, 1994
Afin d'étudier leur aptitude à la combinaison, cinquante-cinq haploïde-doublées (HD) de #Coffea canephora$ ont été croisés avec soit des génotypes hétérozygotes soit des génotypes HD. Trois essais agronomiques ont été établis. Une vigueur hybride marquée
Charrier, André   +2 more
core   +1 more source

TAF15::ZNF384 Mixed Phenotype Acute Leukemia With Complex Karyotype: Case Report With B‐ALL Induction, Blinatumomab Bridging to Allogeneic Transplant and Literature Review

open access: yesClinical Case Reports, Volume 13, Issue 11, November 2025.
TAF15::ZNF384 mixed phenotype acute leukemia with complex karyotype: Case report with B‐ALL Induction, blinatumomab bridging to allogenic transplant and literature review. ABSTRACT CD10, CD19 and MPO in one flow cytometry tube facilitated distinguishing B‐cell acute lymphoblastic leukemia with dim expression of MPO versus B/myeloid mixed phenotype ...
Sarah Blain   +5 more
wiley   +1 more source

Tetraploidy accelerates adaptation under drug selection in a fungal pathogen

open access: yesFrontiers in Fungal Biology, 2022
Baseline ploidy significantly impacts evolutionary trajectories and, specifically, tetraploidy is associated with higher rates of adaptation relative to haploidy and diploidy.
Ognenka Avramovska   +5 more
doaj   +1 more source

Optimization and Evaluation of the bestRAD Sequencing Approach: Towards Ascertainment of the Invasion Routes of the Oriental Fruit Fly, Bactrocera dorsalis

open access: yesMolecular Ecology Resources, Volume 25, Issue 8, November 2025.
ABSTRACT The bestRAD technique is a reduced genome representation approach with high‐capacity sample multiplexing and physical isolation of biotin‐labelled target DNA fragments using streptavidin beads, which should reduce total cost and genotyping errors. While we here formalise the relevance of this approach within the HTS landscape, our foremost aim
Emeline Charbonnel   +7 more
wiley   +1 more source

Case report: Germline CHEK2 mutation is associated with a giant cell glioblastoma

open access: yesFrontiers in Oncology
Giant cell glioblastoma often exhibits genome instability and is frequently associated with mutations in genes involved in DNA repair pathways including TP53 and DNA mismatch repair genes.
Yongfeng Bi   +13 more
doaj   +1 more source

Gene dosage in mammals: characterization of haploid embryonic stem cells [PDF]

open access: yes, 2013
RIGHTS : This article is licensed under the BioMed Central licence at http://www.biomedcentral.com/about/license which is similar to the 'Creative Commons Attribution Licence'.
Leeb, Martin, Wutz, Anton
core   +2 more sources

Genome‐Wide Screening in Haploid Stem Cells Reveals Synthetic Lethality Targeting MLH1 and TP53 Deficient Tumours

open access: yesCell Proliferation, Volume 58, Issue 11, November 2025.
To identify genetic events that can lead to tumour death once either MLH1 or TP53 is mutated, a genome‐wide genetic screening was performed, uncovering a list of putative hits. Synthetic lethal interactions were validated either genetically or chemically by using small molecules that inhibit these genes either in vitro and in vivo.
Rivki Cashman   +12 more
wiley   +1 more source

Integrating Population Genomics and Historical Occurrence Data to Assess the Impact of Land‐Use Changes on Centris Oil Bees in the Brazilian Cerrado

open access: yesMolecular Ecology, Volume 34, Issue 22, November 2025.
ABSTRACT Habitat loss and fragmentation (HLF) are among the major drivers of bee decline, yet closely related species often show contrasting responses depending on their ecological and demographic traits. The Brazilian Cerrado biodiversity hotspot experiences among the world's highest rates of HLF.
Paulo Sousa   +5 more
wiley   +1 more source

Mapping the transcriptional landscape of algal resistance to viral infection reveals a core expression program

open access: yesNew Phytologist, Volume 248, Issue 3, Page 1368-1384, November 2025.
Summary Algal blooms and their demise by viruses drive global‐scale ecological processes in the ocean. These blooms form the foundation of marine food webs, regulate microbial communities, and shape biogeochemical cycles. Although algal populations are constantly infected by viruses, resistant subpopulations frequently emerge after the infection.
Talia S. Shaler   +5 more
wiley   +1 more source

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