Results 81 to 90 of about 6,777 (230)

Infectious Complications During Early Treatment of Childhood Acute Lymphoblastic Leukemia—A Comparison Between the ALLTogether and NOPHO ALL‐2008 Protocols

Pediatric Blood &Cancer, Volume 73, Issue 1, January 2026.
ABSTRACT Introduction Infection remains the most common treatment‐related toxicity of childhood ALL, emphasizing the need to identify patients at risk and to tailor treatment strategies accordingly. Aims The primary aim was to compare infectious toxicity during early treatment for childhood ALL following the ALLTogether and NOPHO ALL‐2008 (ALL‐2008 ...
Hannah van Bunningen, Johannes Fermér, Arja Harila, Susanna Ranta, Isabella Donnér, Anne Wretman, Hartmut Vogt, Anna Sällfors Holmqvist, Anders Valind, Ludvig Henriksson, Jonas Abrahamsson, Magnus Borssén, Anna Nilsson, Mats Heyman   +13 more
wiley   +1 more source

The Overlooked Threat of Global Warming on Elasmobranch Fertility

Fish and Fisheries, Volume 27, Issue 1, Page 41-55, January 2026.
ABSTRACT Climate change is increasingly recognised as a critical threat to global biodiversity, yet its impacts on reproductive processes remain poorly understood in many marine taxa. Elasmobranchs (sharks, skates and rays) represent a particularly vulnerable group due to their peculiar life histories, low fecundity, and diverse reproductive modes.
Noémie Coulon, Eric Feunteun, Alexandre Carpentier, Anne Lizé   +3 more
wiley   +1 more source

Sensitivity and specificity of a novel preimplantation genetic test for aneuploidy (PGT-A) test detecting the presence and origin of the error: creation of haploid embryos as controls

BMJ Connections. Clinical Genetics and Genomics
Introduction Conventional PGT-A methods using NGS sequencing can not detect polyploidy or haploidy, embryo parental origin, or differentiate between mitotic and meiotic abnormalities.
Santiago Munne, Michael Christensen, Hans Kim, Venkatesh Babu, Matthew Prasetyo, Nuno Costa-Borges, Nabil Arrach   +6 more
doaj   +1 more source

TAF15::ZNF384 Mixed Phenotype Acute Leukemia With Complex Karyotype: Case Report With B‐ALL Induction, Blinatumomab Bridging to Allogeneic Transplant and Literature Review

Clinical Case Reports, Volume 13, Issue 11, November 2025.
TAF15::ZNF384 mixed phenotype acute leukemia with complex karyotype: Case report with B‐ALL Induction, blinatumomab bridging to allogenic transplant and literature review. ABSTRACT CD10, CD19 and MPO in one flow cytometry tube facilitated distinguishing B‐cell acute lymphoblastic leukemia with dim expression of MPO versus B/myeloid mixed phenotype ...
Sarah Blain, Brianna Empringham, Talal Mahdi, Benjamin D. Hedley, Jean McGowan‐Jordan, Ruth Padmore   +5 more
wiley   +1 more source

Optimization and Evaluation of the bestRAD Sequencing Approach: Towards Ascertainment of the Invasion Routes of the Oriental Fruit Fly, Bactrocera dorsalis

Molecular Ecology Resources, Volume 25, Issue 8, November 2025.
ABSTRACT The bestRAD technique is a reduced genome representation approach with high‐capacity sample multiplexing and physical isolation of biotin‐labelled target DNA fragments using streptavidin beads, which should reduce total cost and genotyping errors. While we here formalise the relevance of this approach within the HTS landscape, our foremost aim
Emeline Charbonnel, Laure Benoit, Sabine Nidelet, Enrique Ortega‐Abboud, Bernhard Gschloessl, Raphaël Leblois, David Ouvrard, Marie‐Pierre Chapuis   +7 more
wiley   +1 more source

Heat-tolerant maize for rainfed hot, dry environments in the lowland tropics: From breeding to improved seed delivery

Crop Journal, 2023
Climate change-induced heat stress combines two challenges: high day- and nighttime temperatures, and physiological water deficit due to demand-side drought caused by increase in vapor-pressure deficit.
Pervez H. Zaidi, Madhumal Thayil Vinayan, Sudha K. Nair, Prakash H. Kuchanur, Ramesh Kumar, Shyam Bir Singh, Mahendra Prasad Tripathi, Ayyanagouda Patil, Salahuddin Ahmed, Aamir Hussain, Atul Prabhakar Kulkarni, Passang Wangmo, Mitchell R. Tuinstra, Boddupalli M. Prasanna   +13 more
doaj   +1 more source

Doubled haploids of Coffea canephora : development, fertility and agronomic characteristics [PDF]

, 1994
Des haploïde-doublés (HD) de #Coffea canephora$ ont été développés en utilisant les embryons haploïdes qui apparaissent spontanément en association avec la polyembryonie.
Charrier, André, Couturon, Emmanuel, Lashermes, Philippe   +2 more
core   +1 more source

Genome‐Wide Screening in Haploid Stem Cells Reveals Synthetic Lethality Targeting MLH1 and TP53 Deficient Tumours

Cell Proliferation, Volume 58, Issue 11, November 2025.
To identify genetic events that can lead to tumour death once either MLH1 or TP53 is mutated, a genome‐wide genetic screening was performed, uncovering a list of putative hits. Synthetic lethal interactions were validated either genetically or chemically by using small molecules that inhibit these genes either in vitro and in vivo.
Rivki Cashman, Guy Haim‐Abadi, Elyad Lezmi, Hagit Philip, Jonathan Nissenbaum, Ruth Viner‐Breuer, Chen Kozulin, Tamar Golan‐Lev, Aseel Gadban, Shiri Spinner‐Potesky, Ofra Yanuka, Oded Kopper, Nissim Benvenisty   +12 more
wiley   +1 more source

Tetraploidy accelerates adaptation under drug selection in a fungal pathogen

Frontiers in Fungal Biology, 2022
Baseline ploidy significantly impacts evolutionary trajectories and, specifically, tetraploidy is associated with higher rates of adaptation relative to haploidy and diploidy.
Ognenka Avramovska, Ognenka Avramovska, Amanda C. Smith, Amanda C. Smith, Emily Rego, Meleah A. Hickman   +5 more
doaj   +1 more source

Doubled Haploid production in fruit crops. [PDF]

, 2006
The interest of fruit breeders in haploids and doubled haploids (DH), lies in the possibility of shortening the time needed to produce homozygous lines compared to conventional breeding.
GERMANA', Maria
core   +1 more source