Results 91 to 100 of about 407,509 (363)

AsmMix: an efficient haplotype-resolved hybrid de novo genome assembling pipeline

Frontiers in Genetics
Accurate haplotyping facilitates distinguishing allele-specific expression, identifying cis-regulatory elements, and characterizing genomic variations, which enables more precise investigations into the relationship between genotype and phenotype. Recent
Chao Liu, Chao Liu, Pei Wu, Pei Wu, Xue Wu, Xia Zhao, Fang Chen, Xiaofang Cheng, Hongmei Zhu, Hongmei Zhu, Ou Wang, Mengyang Xu, Mengyang Xu   +12 more
doaj   +1 more source

Association of Two Variable Number of Tandem Repeats in the Monoamine Oxidase A Gene Promoter with Schizophrenia

Neuropsychiatric Disease and Treatment, 2021
Takaki Tanifuji,1 Satoshi Okazaki,1 Ikuo Otsuka,1 Tadasu Horai,1 Yutaka Shinko,1 Saehyeon Kim,1 Ichiro Sora,1 Akitoyo Hishimoto1,2 1Department of Psychiatry, Kobe University Graduate School of Medicine, Kobe, Japan; 2Department of Psychiatry, Yokohama ...
Tanifuji T, Okazaki S, Otsuka I, Horai T, Shinko Y, Kim S, Sora I, Hishimoto A   +7 more
doaj  

Molecular characterization, polymorphism and association study of lysozyme gene with milk production and somatic cell trait in Bos indicus × Bos taurus cattle

Animal, 2009
Lysozyme, an anti-bacterial enzyme, is mostly found in the body fluids, various tissues and secretions of animals and humans, and confers immunity against a wide range of bacterial species. The present study was carried out to elucidate the gene sequence
M. Salehin, A.K. Ghosh, P.K. Mallick, T.K. Bhattacharya   +3 more
doaj   +1 more source

Genome-wide superior alleles, haplotypes and candidate genes associated with tolerance on sodic-dispersive soils in wheat (Triticum aestivum L.) [PDF]

, 2022
Darshan Sharma, Roopali Bhoite, Karyn Reeves, Kerrie Forrest, Rosemary H Smith, Mirza A. N. N. U. Dowla   +5 more
openalex   +1 more source

Haplotype-resolved de novo assembly using phased assembly graphs with hifiasm

Nature Methods, 2021
Haoyu Cheng, G. Concepcion, Xiaowen Feng, Haowen Zhang, Heng Li   +4 more
semanticscholar   +1 more source

Distinct effects of complement C4A and C4B copy number in Systemic Sclerosis serological and clinical subtypes

Arthritis &Rheumatology, Accepted Article.
Objective Complement component 4 (C4), encoded by C4A and C4B within the major histocompatibility complex (MHC) on chromosome 6, regulates the immune response and clears immune complexes. Variable copy number (CN) of C4 genes and retroviral HERV‐K element influence its function.
Javier Martínez‐López, Carlos Rangel‐Peláez, Inmaculada Rodriguez‐Martin, Alfredo Guillen‐Del‐Castillo, Carmen P Simeón‐Aznar, José L Callejas, International SSc Group; PRECISESADs Clinical Consortium, Oliver Distler, Susanna M Proudman, Mandana Nikpour, Australian Scleroderma Interest Group (ASIG), Nicolas Hunzelmann, Gianluca Moroncini, Jeska K de Vries‐Bouwstra, Ariane L Herrick, Yannick Allanore, Marta E. Alarcon‐Riquelme, Lorenzo Beretta, Shervin Assassi, Christopher P Denton, Maureen D Mayes, Javier Martin, Marialbert Acosta‐Herrera, Martin Kerick   +23 more
wiley   +1 more source

Uptake of DPYD and UGT1A1 testing in Italy and adherence to pharmacogenetic guidelines: A 5‐year perspective from an EQA provider

British Journal of Clinical Pharmacology, EarlyView.
Aims Pharmacogenetic implementation requires awareness of the state‐of‐the‐art practice of laboratories providing pharmacogenetic testing. This study investigated how pharmacogenetic guidelines and recommendations have been implemented over time by Italian laboratories participating in the external quality assessment (EQA) Pharmaco‐scheme established ...
Rossana Roncato, Samantha Perfler, Diletta Pasin, Elena Peruzzi, Michael Woodcock, Henry Thomas, Rebecca Goodall, Simon J. Patton, Erika Cecchin   +8 more
wiley   +1 more source

rehh 2.0: a reimplementation of the R package rehh to detect positive selection from haplotype structure

bioRxiv, 2016
Identifying genomic regions with unusually high local haplotype homozygosity represents a powerful strategy to characterize candidate genes responding to natural or artificial positive selection.
M. Gautier, A. Klassmann, R. Vitalis
semanticscholar   +1 more source

Exosome as bioactive nanovesicle for diagnostic and therapeutic applications in periodontitis

BMEMat, EarlyView.
This review introduces the mechanism that exosomes participate in the pathogenesis of periodontitis and their potential as biomarkers for early diagnosis and summarizes the application of cell‐ or plant‐derived exosomes or engineered exosomes in periodontitis or periodontal regeneration while proposing the perspective of translational application of ...
Yu Wang, Yuchen Li, Yunfan Zhang, Chenshuang Li, Yifan Lin, Si Chen, Bing Han   +6 more
wiley   +1 more source

forqs: Forward-in-time Simulation of Recombination, Quantitative Traits, and Selection [PDF]

, 2013
forqs is a forward-in-time simulation of recombination, quantitative traits, and selection. It was designed to investigate haplotype patterns resulting from scenarios where substantial evolutionary change has taken place in a small number of generations ...
Kessner, Darren, Novembre, John
core