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Results 111 to 120 of about 277,505 (282)

Cutaneous Squamous Cell Carcinoma Amongst Solid Organ Transplant Recipients: A Systematic Review of Molecular Alterations

JEADV Clinical Practice, EarlyView.
ABSTRACT Background As solid organ transplantation becomes more prevalent, more patients are living on long‐term immunosuppression, greatly increasing the risk of cutaneous squamous cell carcinoma (cSCC). Although significant improvements have been achieved in the treatment of cSCC, further studies are needed to identify the specific protein expression
William Murray +8 more
wiley +1 more source

Predicted genetic consequences of alternative population control strategies for North American plains bison in Yellowstone National Park

The Journal of Wildlife Management, EarlyView.
Management of bison in Yellowstone National Park under the available strategies that maintained ≥3,500 individuals (1:1 sex ratio), removed <40% of the population at a time and prioritized relatives for removal were predicted to maintain genetic variation at levels consistent with long‐term conservation (>95% of existing variation).
Shawna J. Zimmerman +2 more
wiley +1 more source

Genetic dissection of stem and leaf rachis prickles in diploid rose using a pedigree-based QTL analysis

Frontiers in Plant Science
IntroductionPrickles are often deemed undesirable traits in many crops, including roses (Rosa sp.), and there is demand for rose cultivars with no or very few prickles.
Zena J. Rawandoozi +5 more
doaj +1 more source

Genome‐Wide Assessment Reveals Ancestral Differences in Homozygosity Patterns Potentially Linked to Parkinson's Disease Etiology

Movement Disorders, EarlyView.
Abstract Background Recessive genetic variation and extended runs of homozygosity (ROHs) may contribute to the unexplained heritability of Parkinson's disease (PD), particularly in diverse and understudied populations. Objective We conducted the first large‐scale, multi‐ancestral investigation of PD to examine the impact of genome‐wide homozygosity on ...
Kathryn Step +680 more
wiley +1 more source

Deciphering of Genomic Loci Associated with Alkaline Tolerance in Soybean [Glycine max (L.) Merr.] by Genome-Wide Association Study

Plants
Alkaline stress is one of the major abiotic constraints that limits plant growth and development. However, the genetic basis underlying alkaline tolerance in soybean [Glycine max (L.) Merr.] remains largely unexplored.
Xinjing Yang +8 more
doaj +1 more source

A gentle introduction to the discrete Laplace method for estimating Y-STR haplotype frequencies

, 2013
Y-STR data simulated under a Fisher-Wright model of evolution with a single-step mutation model turns out to be well predicted by a method using discrete Laplace distributions.Comment: 18 pages, 5 ...
Andersen, Mikkel Meyer, Eriksen, Poul Svante, Morling, Niels +2 more
core

Biomarkers of Leucine‐Rich Repeat Kinase 2 (LRRK2) and Lysosomal Dysfunction in Progressive Supranuclear Palsy

Movement Disorders, EarlyView.
Abstract Background Common and rare genetic variants in leucine‐rich repeat kinase 2 (LRRK2) have been linked with sporadic and familial Parkinson's disease (PD). Recently, we discovered that common genetic variation near the LRRK2 locus determined survival in progressive supranuclear palsy (PSP).
Louise‐Kristine Nielsen +27 more
wiley +1 more source

Prognosis in Parkinson's Disease: An Individual Patient Data Meta‐Analysis of Six European Incidence Cohorts

Movement Disorders, EarlyView.
Abstract Background An accurate understanding of prognosis in Parkinson's disease (PD) is important for patient information provision, personalized treatment, and clinical trial design, but most previous research has been biased towards younger, healthier patients.
Angus D. Macleod +72 more
wiley +1 more source

Inheritance of bovine lymphocyte intestinal retention defect disorder affects Holstein production performance and longevity

Journal of Dairy Science
: Improved methods previously developed for tracking new mutations within existing haplotypes for cholesterol deficiency (HCD) and muscle weakness (HMW) now also were applied to track the bovine lymphocyte intestinal retention defect (BLIRD) discovered ...
A. Al-Khudhair +3 more
doaj +1 more source

Stable Carbon and Nitrogen Isotope Analysis Explores Diverse Domestic Goose Management Practices in Medieval and Postmedieval Russia

International Journal of Osteoarchaeology, EarlyView.
ABSTRACT Studying goose domestication through archaeological finds has been challenging due to the similar skeletal morphology of the European domestic goose and its wild progenitor, the greylag goose (Anser anser). We analyzed stable carbon (δ13C) and nitrogen (δ15N) isotopes from bone collagen of subfossil domestic and potentially domestic geese to ...
Johanna Honka +7 more
wiley +1 more source

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