Results 101 to 110 of about 290,368 (328)

When numbers matter: Rethinking the role of gene duplication on short evolutionary timescales

American Journal of Botany, EarlyView.
Freja Lindstedt, Qiujie Zhou, Pascal Milesi   +2 more
wiley   +1 more source

Prevalence of Actionable Pharmacogenetic Genotype Frequencies, Cautionary Medication Use, and Polypharmacy in Community‐Dwelling Older Adults

Clinical Pharmacology &Therapeutics, EarlyView.
Older adults (65 years and over) frequently manage complex medication regimens and are vulnerable to adverse drug reactions and treatment inefficacies, some of which could be preventable with pharmacogenetics (PGx)‐guided prescribing. This study examined the prevalence of actionable PGx genotypes (i.e., those linked to a guideline that recommends a ...
Chad A. Bousman, Ankita Narang, Ziad Al Bkhetan, Robyn L. Woods, Suzanne G. Orchard, Alice J. Owen, Michelle A. Fravel, Julia Gilmartin‐Thomas, Joanne Ryan, Peter D. Fransquet, Rory Wolfe, Chenglong Yu, John J. McNeil, Paul Lacaze, Michael E. Ernst   +14 more
wiley   +1 more source

Testing the core–periphery hypothesis: a standardised multi‐phylum assessment of genetic diversity of marine coastal species

Ecography, EarlyView.
The core–periphery hypothesis (CPH) predicts that genetic diversity is greatest at the centre and lowest at the edges of a species' distribution because genetic diversity is a function of a species' abundance, which is also expected to be greatest at the centre and lowest at the edges of the distribution. Variants of the CPH include the ‘Ramped North' (
Daniel Cárcamo, Mailiu Díaz Peña, Jonathan P. A. Gardner   +2 more
wiley   +1 more source

Genetic diversity of Toll-like receptor 5 among pig populations

Genetics and Molecular Biology, 2013
The Toll-like receptor 5 (TLR5) recognizes flagellin of Gram-positive and -negative bacteria and plays an important role in the host defense system. Here, we surveyed single nucleotide polymorphisms (SNPs) in the coding sequence of the porcine TLR5 gene ...
Xiuqin Yang, Haitao Li, Qingzhi Guan, Di Liu   +3 more
doaj  

MTHFR C677T and A1298C Genotypes and Haplotypes in Slovenian Couples with Unexplained Infertility Problems and in Embryonic Tissues from Spontaneous Abortions

Balkan Journal of Medical Genetics, 2013
The objective of this study was to analyze the methylenetetrahydrofolate reductases (MTHFRs) C677T and A1298C genotype distributions in couples with unexplained fertility problems (UFP) and healthy controls, and to analyze the genotype and haplotype ...
Stangler Herodež Š, Zagradišnik B, Erjavec Škerget A, Zagorac A, Takač I, Vlaisavljević V, Lokar L, Kokalj Vokač N   +7 more
doaj   +1 more source

A systematic review evaluating the performance of eDNA methods relative to conventional methods for biodiversity monitoring

Ecography, EarlyView.
The rapid adoption of environmental DNA (eDNA) methods has drastically changed biodiversity monitoring efforts. It is often claimed that eDNA methods are more sensitive and efficient than conventional biodiversity monitoring methods, but it is often unclear what metrics support this claim.
Nicholas J. Iacaruso, Olivia P. Reves, Sara J. Merkelz, Cassidy L. Waldrep, Mark A. Davis   +4 more
wiley   +1 more source

Single-nucleotide polymorphisms, mapping and association analysis of 1-FFT-A1 gene in wheat

Journal of Integrative Agriculture, 2017
Fructans are major nonstructural carbohydrates in wheat (Triticum aestivum L.). Fructan 1-fructosyltransferase (1-FFT) is the key enzyme in fructan biosynthesis. In the present study, 96 sequence variants were detected in the 1-FFT-A1 gene among 26 wheat
Ai-qin YUE, Ang LI, Xin-guo MAO, Xiao-ping CHANG, Run-zhi LI, Rui-lian JING   +5 more
doaj  

Phylogenetical Relationships between Kejobong Goat and Other Goats Based on Mt-DNA D-loop Sequence Analysis

Tropical Animal Science Journal, 2018
The aim of this study was to investigate phylogenetical relationships between Kejobong goat and Kacang goat as well as Etawah Grade goat using genetic diversity, haplotype, and genetic distance analysis based on D-loop sequences.
D. A. Lestari, E. Purbowati, S. Sutopo, E. Kurnianto   +3 more
doaj   +1 more source

Derivation of mutantt-haplotypes of the mouse by presumed duplication or deletion [PDF]

, 1977
Mary F. Lyon, Kathleen B. Bechtol
openalex   +1 more source

Splitting trees with neutral Poissonian mutations I: Small families [PDF]

, 2010
We consider a neutral dynamical model of biological diversity, where individuals live and reproduce independently. They have i.i.d. lifetime durations (which are not necessarily exponentially distributed) and give birth (singly) at constant rate b.
Champagnat, Nicolas, Lambert, Amaury
core   +1 more source