Statistical methods for detecting genes associated with sperm competition in natural populations of Drosophila, using blocks of tightly linked single nucleotide polymorphisms : a thesis presented in partial fulfilment of the requirements for the degree of Master of Science in Statistics at Massey University, Albany, New Zealand [PDF]
, 2007 The purpose of the project is to develop statistical methods for detecting genes associated with sperm competition in natural populations of Drosophila (fruit flies). The flies' genotype information given by Fiumera et al.
Werner, Lillian Li
core
, 2007 Statistically resolving the underlying haplotype pair for a genotype measurement is an important intermediate step in gene mapping studies, and has received much attention recently. Consequently, a variety of methods for this problem have been developed.
Kääriäinen, Matti +3 more
openaire +2 more sources
Schizophrenia Genetics Modulates Clinical Depressive Features
American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, EarlyView.ABSTRACT Schizophrenia (SCZ) genetic liability, quantified by polygenic scores (PGS), may influence clinical phenotypes in major depressive disorder (MDD). We investigated the effect of the SCZ‐PGS derived from the latest SCZ genome‐wide association study (GWAS) on MDD symptom severity, comorbidities, and treatment outcomes.
Alessandro Serretti +13 more
wiley +1 more source
Journal of Lipid Research, 2006 Paraoxonase 1 (PON1) activity is consistently predictive of vascular disease, although the genotype at four functional PON1 polymorphisms is not. To address this inconsistency, we investigated the role of all common PON1 genetic variability, as measured ...
Christopher S. Carlson +13 more
doaj +1 more source
Depression Polygenicity and Disease Activity and Disability Worsening in Multiple Sclerosis
Annals of Neurology, EarlyView.Objective A better understanding of factors associated with multiple sclerosis (MS) disease activity and disability is needed. Given the strong link between comorbid depression and MS disease activity and disability, we aimed to determine whether the depression genetic burden, as modelled using its polygenic score, is associated with MS disease ...
Ali Manouchehrinia +24 more
wiley +1 more source
A Major Root Architecture QTL Responding to Water Limitation in Durum Wheat
Frontiers in Plant Science, 2019 The optimal root system architecture (RSA) of a crop is context dependent and critical for efficient resource capture in the soil. Narrow root growth angle promoting deeper root growth is often associated with improved access to water and nutrients in ...
Samir Alahmad +13 more
doaj +1 more source
Biallelic Variants in the DARS2 Gene as a Novel Cause of Axonal Charcot–Marie–Tooth Disease
Annals of Neurology, EarlyView.Objective Charcot–Marie–Tooth (CMT) disease is a heterogeneous group of genetic neuropathies, with >90 genes identified. Several aminoacyl‐tRNA synthetases have been linked to CMT. DARS2, encoding the mitochondrial aspartyl‐tRNA synthetase, has been typically associated with leukoencephalopathy with brainstem and spinal cord involvement and lactate ...
Berta Estévez‐Arias +23 more
wiley +1 more source
The Variability of Cytoplasmic DNA Haplotypes of Norway Spruce in the Provenance Trials [PDF]
Сибирский лесной журнал, 2014 A genetic analysis of mitochondrial (mtDNA) and chloroplast (cpDNA) genomes of 27 climatypes of Norway spruce was conducted in the provenance (Cherikov forestry district, Republic of Belarus).
V. E. Padutov +4 more
doaj
Genetic diversity and prevalence of CCR2-CCR5 gene polymorphisms in the Omani population
Genetics and Molecular Biology, 2014 Polymorphisms in the regulatory region of the CCR5 gene affect protein expression and modulate the progress of HIV-1 disease. Because of this prominent role, variations in this gene have been under differential pressure and their frequencies vary among ...
Samira H. Al-Mahruqi +5 more
doaj +1 more source
in Vivo Cooperation of Murine Lymphocytes Sharing One Haplotype of the Transplantation Genes: A Requirement for Tolerance of the Nonshared Haplotype [PDF]
, 1979 Matko Marušić, Eugene H. Perkins
openalex +1 more source