Results 231 to 240 of about 209,468 (302)

Immune‐competent organ‐on‐chip methodologies to study type 1 diabetes

Diabetic Medicine, EarlyView.
Abstract Aims Type 1 diabetes (T1D) is a self‐driving autoimmune condition leading to the death of insulin‐producing β‐cells of the pancreas. β‐cell‐reactive immune cell extravasation into the intra‐islet space is fuelled by a cycle of inflammation including immune, vascular and endocrine dysfunction. Since clinical pancreatic biopsy is contraindicated,
Maja Witowska, Luigi Margiotta‐Casaluci, Periklis Pantazis, Margarita Dominguez‐Villar, Victoria Salem   +4 more
wiley   +1 more source

Molecular Characterization of Lumpy Skin Disease Virus in Bulgaria: Phylogenetic Insights Based on the RPO30 Gene. [PDF]

Vet Sci
Goujgoulova G, Koev K, Stoimenov G.
europepmc   +1 more source

Polygenic Risk Scores for Islet Autoantibody Positive Early‐Stage Type 1 Diabetes Pre‐Screening

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims To develop a sex‐aligned polygenic risk score (PRS) for early‐stage type 1 diabetes (T1D) in children without a first‐degree family history of T1D. Materials and Methods Global Single Nucleotide Polymorphism (SNP) Array was performed in 16 335 individuals without a first‐degree family history of T1D, including 13 956 newborns from the ...
Jose Zapardiel‐Gonzalo, Christiane Winkler, Florian Haupt, Manja Jolink, Alexandra Käßl, Konstantinos Hatzikotoulas, Anette‐G. Ziegler, Ezio Bonifacio   +7 more
wiley   +1 more source

The genome sequence of the Purple-barred Yellow, <i>Lythria purpuraria</i> (Linnaeus, 1758) (Lepidoptera: Geometridae). [PDF]

Wellcome Open Res
Vila R, Toro-Delgado E, Wright CJ, Meier JI, Blaxter ML, Wellcome Sanger Institute Tree of Life Management, Samples and Laboratory team, Wellcome Sanger Institute Scientific Operations: Sequencing Operations, Wellcome Sanger Institute Tree of Life Core Informatics team, Tree of Life Core Informatics collective, Project Psyche Community.   +10 more
europepmc   +1 more source

An AI‐Driven Biomass Estimation Tool Enabling Population‐ and Specimen‐Level Variation Analyses: A Case Study on Parasitoid Flies

Entomologia Experimentalis et Applicata, EarlyView.
We present the first ecological application of InsectMorphoAI, a tool estimating curvilinear body length and body volume from two‐dimensional fly images. Applying this approach to tachinid flies from a Mediterranean forest near Rome, Italy, we quantified species composition, abundance, body size, body proportions, and biomass proxies in assemblages ...
Ascenzi Aleida, Shirali Hossein, Di Lorenzo Noemi, Nania Dario, Wührl Lorenz, Pylatiuk Christian, Meier Rudolf, Cerretti Pierfilippo   +7 more
wiley   +1 more source

CRISPR-HAWK: haplotype- and variant-aware guide design toolkit for CRISPR-Cas. [PDF]

Bioinformatics
Kumbara A, Tognon M, Carone G, Fontanesi A, Bombieri N, Giugno R, Pinello L.   +6 more
europepmc   +1 more source

Climatic, biogeographic and ecological factors influence the spatial patterns of odd‐ and even‐year dominance in biennial European butterflies and burnet moths

Ecological Entomology, EarlyView.
250,000 observations of 7 annual, 11 biennial and 4 flexible lepidoptera species in the Alps and over 150,000 observations of 5 biennial species from Scandinavia were analysed. Maps show distinct patterns of different species that fly predominantly in odd or even years in the researched areas.
Robert Birch, Kay Lucek, Yannick Chittaro, Gregor Markl   +3 more
wiley   +1 more source

Mitochondrial Phylogeography of the Proboscis Monkey (<i>Nasalis larvatus</i>) Reveals Riverine and Coastal Population Structure Across Eastern Borneo. [PDF]

Ecol Evol
Atmoko T, Putra WPB, Qiptiyah M, Prihatini I, Mukhlisi, Akbar MA, Yamada C, Ophinni Y.   +7 more
europepmc   +1 more source

Ecology and morphology as drivers of passerine song differentiation across an island archipelago

Ibis, EarlyView.
We conducted an integrative analysis to explore possible explanations for the song differentiation in bird populations from the mainland and the Tres Marías Archipelago (TMA) on the central‐western Pacific coast of Mexico. We first analysed the effect of isolation on cultural transmission by comparing repertoire size and genetic fixation in four ...
Marco F. Ortiz‐Ramírez, Eduardo Iñigo‐Elías, Marcelo Araya‐Salas, Fernanda Bribiesca‐Contreras, Luis. A. Sánchez‐González, Juan Francisco Ornelas, Adolfo G. Navarro‐Sigüenza   +6 more
wiley   +1 more source

The genome sequence of kidney vetch, <i>Anthyllis vulneraria</i> L. (Fabales: Fabaceae). [PDF]

Wellcome Open Res
Ruhsam M, Hollingsworth PM, Royal Botanic Garden Edinburgh Genome Acquisition Lab, Plant Genome Sizing Collective, Darwin Tree of Life Barcoding collective, Wellcome Sanger Institute Tree of Life Management, Samples and Laboratory team, Wellcome Sanger Institute Scientific Operations: Sequencing Operations, Wellcome Sanger Institute Tree of Life Core Informatics team, Tree of Life Core Informatics collective, Darwin Tree of Life Consortium.   +10 more
europepmc   +1 more source