Results 261 to 270 of about 209,468 (302)

Haplotype Inference

2017
Haplotypes, as they specify linkage patterns between individual nucleotide variants, confer critical information for understanding the genetics of human diseases. However, haplotype information is not directly obtainable from high-throughput genotyping platforms.
Sunah, Song, Xin, Li, Jing, Li
openaire   +2 more sources

Empirical Exploration of Perfect Phylogeny Haplotyping and Haplotypers

2003
The next high-priority phase of human genomics will involve the development of a full Haplotype Map of the human genome [15]. It will be used in large-scale screens of populations to associate specific haplotypes with specific complex genetic-influenced diseases.
Ren Hua Chung, Dan Gusfield
openaire   +2 more sources

Haplotype Inference and Haplotype Information

2004
Haplotypes have become increasingly popular because of the abundance of single nucleotide polymorphisms (SNPs) and the limited power of the single-locus analyses. To contend with some weaknesses of the existing haplotype inference methods, we propose new algorithms based on the partition-ligation idea.
openaire   +1 more source

Multifactor Dimensionality Reduction for Detecting Haplotype-Haplotype Interaction

2009 Sixth International Conference on Fuzzy Systems and Knowledge Discovery, 2009
The multifactor dimensionality reduction (MDR) is a model-free approach that can identify SNP × SNP effects in a case-control study. In this study, we extended MDR to identify interactions among haplotypes (Hap-MDR). With Hap-MDR, multilocus haplotype genotypes were pooled into high-risk and low-risk groups, effectively reducing the haplotype genotypes
Yongshuai Jiang, Ruijie Zhang, Guiyou Liu, Zhen Wang, Zhiqiang Chen, Peng Sun, Chen Huang, Xuehong Zhang   +7 more
openaire   +2 more sources

Haplotypes and MS

Neurology, 1989
D A, Francis, J R, Batchelor
openaire   +2 more sources

Algorithms for inferring haplotypes

Genetic Epidemiology, 2004
AbstractHaplotype phase information in diploid organisms provides valuable information on human evolutionary history and may lead to the development of more efficient strategies to identify genetic variants that increase susceptibility to human diseases. Molecular haplotyping methods are labor‐intensive, low‐throughput, and very costly.
openaire   +2 more sources

Haplotype

2008
  +5 more sources

Haplotyping

2023
openaire   +1 more source

Haplotype

2006
  +6 more sources

De Novo Assembly of Haplotype-Resolved Genomes With Trio Binning

Nature Biotechnology, 2018
John L. Williams, Stefan Hiendleder, Brian P Walenz   +2 more
exaly