Results 71 to 80 of about 275,736 (271)

MONOAMINE OXIDASE A (MAOA), CHILDHOOD TRAUMA, ALCOHOLISM AND AGGRESSION [PDF]

, 2008
Women who have experienced childhood sexual abuse (CSA) have an increased risk of alcoholism and antisocial personality disorder (ASPD). Among males, a functional polymorphism (MAOA-LPR, monoamine oxidase A linked polymorphic region) in the promoter ...
DUCCI, FRANCESCA
core  

Pure Parsimony Xor Haplotyping [PDF]

IEEE/ACM Transactions on Computational Biology and Bioinformatics, 2009
The haplotype resolution from xor-genotype data has been recently formulated as a new model for genetic studies. The xor-genotype data is a cheaply obtainable type of data distinguishing heterozygous from homozygous sites without identifying the homozygous alleles.
BONIZZONI, PAOLA, DELLA VEDOVA, GIANLUCA, Dondi, R, PIROLA, YURI, Rizzi, R.   +4 more
openaire   +8 more sources

Profiling Localized Immunomodulation and Drug Biodistribution within a Subcutaneous Vascularized Niche for Cell Transplantation

Advanced Science, EarlyView.
We studied how five common immunosuppressants behave when delivered directly to a transplant site instead of systemically. Using a vascularized implant for islet transplantation, we show that local delivery protects grafts, limits drug spread to the rest of the body, and produces distinct immune signatures.
Jocelyn Nikita Campa‐Carranza, Simone Capuani, Melissa A. Willman, Alexander Rabassa, Ashley L. Joubert, Tommaso Bo, Letizia Franco, Marzia Conte, Ana L. Anaya‐García, Gabrielle E. Rome, Rim Ouni, Henry J. Seaborne, Camden A. Caffey, Dora M. Berman, Junjun Zheng, Jesus Paez‐Mayorga, Corrine Ying Xuan Chua, Shu Hsia Chen, Norma S. Kenyon, Alessandro Grattoni   +19 more
wiley   +1 more source

Effects of the number of markers per haplotype and clustering of haplotypes on the accuracy of QTL mapping and prediction of genomic breeding values [PDF]

, 2009
The aim of this paper was to compare the effect of haplotype definition on the precision of QTL-mapping and on the accuracy of predicted genomic breeding values.
Mario PL Calus, Theo HE Meuwissen, Jack J Windig, Egbert F Knol, Chris Schrooten, Addie LJ Vereijken, Roel F Veerkamp, THE Meuwissen, THE Meuwissen, MPL Calus, L Grapes, L Grapes, K Yu, HG deVries, D Habier, WM Muir, TR Solberg, M Lynch, T Druet, B Hayes, DS Falconer, A Legarra, RL Fernando, THE Meuwissen, WG Hill, BJ Hayes, EJ Pollak, L Ronnegard, E Uleberg   +28 more
core   +3 more sources

Long-range, high-throughput haplotype determination via haplotype-fusion PCR and ligation haplotyping [PDF]

Nucleic Acids Research, 2008
Ligation Haplotyping is a robust, novel method for experimental determination of haplotypes over long distances, which can be applied to assaying both sequence and structural variation. The simplicity and efficacy of the method for genotyping large chromosomal rearrangements and haplotyping SNPs over long distances make it a valuable and powerful ...
Turner, Daniel J., Tyler-Smith, Chris, Hurles, Matthew E.   +2 more
openaire   +2 more sources

A Scalable Framework for Comprehensive Typing of Polymorphic Immune Genes from Long‐Read Data

Advanced Science, EarlyView.
SpecImmune introduces a unified computational framework optimized for long‐read sequencing to resolve over 400 highly polymorphic immune genes. This scalable approach achieves high‐resolution typing, enabling the discovery of cross‐family co‐evolutionary networks and population‐specific diversity.
Shuai Wang, Xuedong Wang, Mengyao Wang, Qian Zhou, Lusheng Wang, Shuai Cheng Li   +5 more
wiley   +1 more source

Linking unfounded beliefs to genetic dopamine availability

Frontiers in Human Neuroscience, 2015
Unfounded convictions involving beliefs in the paranormal, grandiosity ideas or suspicious thoughts are endorsed at varying degrees among the general population.
Katharina eSchmack, Hannes eRössler, Maria eSekutowicz, Eva J Brandl, Daniel J Mueller (Müller), Predrag ePetrovic, Philipp eSterzer   +6 more
doaj   +1 more source

Demography and the age of rare variants

, 2014
Large whole-genome sequencing projects have provided access to much of the rare variation in human populations, which is highly informative about population structure and recent demography. Here, we show how the age of rare variants can be estimated from
Mathieson, Iain, McVean, Gil
core   +3 more sources

Haplotype inference for present–absent genotype data using previously identified haplotypes and haplotype patterns [PDF]

Bioinformatics, 2007
AbstractMotivation: Killer immunoglobulin-like receptor (KIR) genes vary considerably in their presence or absence on a specific regional haplotype. Because presence or absence of these genes is largely detected using locus-specific genotyping technology, the distinction between homozygosity and hemizygosity is often ambiguous.
Yun Joo, Yoo, Jianming, Tang, Richard A, Kaslow, Kui, Zhang   +3 more
openaire   +2 more sources

Additive and Partially Dominant Effects from Genomic Variation Contribute to Rice Heterosis

Advanced Science, EarlyView.
Additive and partially dominant effects, namely at mid‐parent levels or values between mid‐parent and parental levels, respectively, are the predominant inheritance patterns of heterosis‐associated molecules. These two genetic effects contribute to heterosis of agronomic traits in both rice and maize, as well as biomass heterosis in Arabidopsis ...
Zhiwu Dan, Yunping Chen, Wei Zhou, Yanghong Xu, Junran Huang, Yi Chen, Jizhou Meng, Guoxin Yao, Wenchao Huang   +8 more
wiley   +1 more source