Results 71 to 80 of about 290,368 (328)

FemXpress: Systematic Analysis of X Chromosome Inactivation Heterogeneity in Female Single‐Cell RNA‐Seq Samples

Advanced Science, EarlyView.
FemXpress is a computational tool that leverages X‐linked single nucleotide polymorphisms (SNPs) to group cells by the origin of the inactivated X chromosome in female single‐cell RNA sequencing (scRNA‐Seq) data. It demonstrates strong performance on both simulated and real datasets without requiring parental genomic information, and can also identify ...
Xin Wang, Yingke Ma, Fan Li, Wentao Cui, Tianshi Pan, Siqi Wang, Sinan Ma, Qingtong Shan, Chao Liu, Yukai Wang, Ying Zhang, Yuanchun Zhou, Wei Li, Pengfei Wang, Qi Zhou, Guihai Feng   +15 more
wiley   +1 more source

QTL Mapping and Data Mining to Identify Genes Associated With the Sinorhizobium fredii HH103 T3SS Effector NopD in Soybean

Frontiers in Plant Science, 2020
In some legume–rhizobium symbioses, host specificity is influenced by rhizobial type III effectors-nodulation outer proteins (Nops). However, the genes encoding host proteins that interact with Nops remain unknown.
Jinhui Wang, Jieqi Wang, Chao Ma, Ziqi Zhou, Decheng Yang, Junzan Zheng, Qi Wang, Huiwen Li, Hongyang Zhou, Zhijun Sun, Hanxi Liu, Jianyi Li, Lin Chen, Qinglin Kang, Zhaoming Qi, Hongwei Jiang, Rongsheng Zhu, Xiaoxia Wu, Chunyan Liu, Qingshan Chen, Dawei Xin   +20 more
doaj   +1 more source

High-throughput haplotype determination over long distances by haplotype fusion PCR and ligation haplotyping [PDF]

Nature Protocols, 2009
When combined with haplotype fusion PCR (HF-PCR), ligation haplotyping is a robust, high-throughput method for empirical determination of haplotypes, which can be applied to assaying both sequence and structural variation over long distances. Unlike alternative approaches to haplotype determination, such as allele-specific PCR and long PCR, HF-PCR and ...
Daniel J. Turner, Matthew E. Hurles
openaire   +3 more sources

Privacy-Preserving Genetic Relatedness Test [PDF]

, 2016
An increasing number of individuals are turning to Direct-To-Consumer (DTC) genetic testing to learn about their predisposition to diseases, traits, and/or ancestry. DTC companies like 23andme and Ancestry.com have started to offer popular and affordable
De Cristofaro, Emiliano, Liang, Kaitai, Zhang, Yuruo   +2 more
core   +1 more source

Subgenome Partitioning and Polyploid Genome Evolution in the Loach Family Botiidae (Order Cypriniformes)

Advanced Science, EarlyView.
This study investigates subgenome evolution and polyploidy in Cypriniformes fish, revealing complex phylogenetic relationships and genomic dynamics. By applying advanced subgenome partitioning methods, it uncovers novel insights into transposon activity and gene fractionation.
Yunyun Lv, Jia Li, Yanping Li, Yu Huang, Qiang Lai, Zhengyong Wen, Jun Wang, Yang He, Jinrong Shi, Zejin Huang, Ying Jiang, Yves Van de Peer, Qiong Shi, Biwen Xie, Yongming Wang   +14 more
wiley   +1 more source

Variants in the Upstream Region of the Insulin Receptor Substrate-1 Gene Is Associated with Major Depressive Disorder in the Han Chinese Population

Neuropsychiatric Disease and Treatment, 2020
Fan Wang,1,2 Shunying Yu,3 Rubai Zhou,1 Ruizhi Mao,1 Guoqing Zhao,1,4 Xiaoyun Guo,1 Qingqing Xu,3 Jun Chen,1 Chen Zhang,1 Yiru Fang1,5,6 1Division of Mood Disorders, Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine ...
Wang F, Yu S, Zhou R, Mao R, Zhao G, Guo X, Xu Q, Chen J, Zhang C, Fang Y   +9 more
doaj  

The Variability of Cytoplasmic DNA Haplotypes of Norway Spruce in the Provenance Trials [PDF]

Сибирский лесной журнал, 2014
A genetic analysis of mitochondrial (mtDNA) and chloroplast (cpDNA) genomes of 27 climatypes of Norway spruce was conducted in the provenance (Cherikov forestry district, Republic of Belarus).
V. E. Padutov, A. I. Sidor, D. I. Kagan, O. A. Kovalevich, S. N. Veras   +4 more
doaj  

Two co‐inherited novel SNPs in the MC4R gene related to live body weight and hormonal assays in Awassi and Arabi sheep breeds of Iraq

Veterinary Medicine and Science, 2021
Melanocortin‐4 receptor (MC4R) gene plays a key role in the regulation of body weight and energy homeostasis. This study aims to evaluate the association of single nucleotide polymorphisms (SNPs) of the MC4R gene with live body weight and hormonal assays
Tahreer M. Al‐Thuwaini, Mohammed Baqur S. Al‐Shuhaib, Frederic Lepretre, Halla Hassan Dawud   +3 more
doaj   +1 more source

Polymorphisms in the Human Aquaporin 4 Gene Are Associated With Schizophrenia in the Southern Chinese Han Population: A Case–Control Study

Frontiers in Psychiatry, 2020
BackgroundIn psychiatric illness, pathogenic role of neuroinflammation has been supported by multiple lines of evidence. Astrocytes contribute to the blood-brain barrier (BBB) with formation of the “glymphatic” drainage system of the central nervous ...
Yung-Fu Wu, Yung-Fu Wu, Huey-Kang Sytwu, For-Wey Lung, For-Wey Lung   +4 more
doaj   +1 more source

Long‐Read Whole‐Genome Sequencing Uncovers a Deletion Upstream to HOXD13 Causing Synpolydactyly

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Synpolydactyly (SPD) is a heterogeneous distal‐limb malformation syndrome, characterized by webbing and duplication of adjacent digits. SPD1, the most common type, is attributed to disease‐causing variants in HOXD13, a transcription factor in the HOXD cluster that is essential for limb development. Here, we present a challenging exome‐negative
Jonathan Rips, Rivka Birnbaum, Chaim Jalas, Ayala Frumkin, Shamir Zenvirt, Julia Rachanaev, Avraham Shaag, Tamar Harel, Orly Elpeleg, Hagar Mor‐Shaked   +9 more
wiley   +1 more source