Results 1 to 10 of about 223,041 (368)
A cladistic analysis of phenotypic associations with haplotypes inferred from restriction endonuclease mapping and DNA sequence data. III. Cladogram estimation. [PDF]
Genetics, 1992 We previously developed a cladistic approach to identify subsets of haplotypes defined by restriction endonuclease mapping or DNA sequencing that are associated with significant phenotypic deviations.
Alan R. Templeton +2 more
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Association of HLA Genotype and Fulminant Type 1 Diabetes in Koreans [PDF]
Genomics & Informatics, 2015 Fulminant type 1 diabetes (T1DM) is a distinct subtype of T1DM that is characterized by rapid onset hyperglycemia, ketoacidosis, absolute insulin deficiency, and near normal levels of glycated hemoglobin at initial presentation.
Soo Heon Kwak +8 more
doaj +1 more source
Frontiers in Genetics, 2022 We describe a genome-wide analytical approach, SNP and Haplotype Regional Heritability Mapping (SNHap-RHM), that provides regional estimates of the heritability across locally defined regions in the genome.
Richard F. Oppong +10 more
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Determination of C,c,E and e Antigens Prevalence in Rh D Negative Individuals: Is it Good Exercise with Utilities in Clinical Blood Transfusion Practices? [PDF]
Journal of Clinical and Diagnostic Research, 2022 Introduction: Besides D antigen, C,c,E and e antigens of Rh blood group system are the most important antigens involved in alloimmunisation. The prevalence of C,c,E and e antigens in Rh D negative individuals in local population has many utilities in ...
Manoj A Kahar
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High fraction of silent recombination in a finite population two-locus neutral birth-death-mutation model [PDF]
Phys. Rev. E 106, 024409 (2022), 2021 A precise estimate of allele and haplotype polymorphism is of great interest in theoretical population genetics, but also has practical applications, such as bone marrow registries management. Allele polymorphism is driven mainly by point mutations, while haplotype polymorphism is also affected by recombination. Current estimates treat recombination as
arxiv +1 more source
Evaluation of cytochrome b sequence to identify Leishmania species and variants: the case of Panama [PDF]
Memorias do Instituto Oswaldo Cruz, 2021 BACKGROUND The genetic heterogeneity of Leishmania parasites is a major factor responsible for the wide variety of Leishmania-associated manifestations.
Michelle Davila +4 more
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Frontiers in Genetics, 2022 Rice grain shape is a major determinant of rice market value and the end-use. We mapped quantitative trait loci (QTL) for grain shape traits in a bi-parental recombinant inbred line population (Trenasse/Jupiter) and discovered two major grain length QTLs—
Brijesh Angira +2 more
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Plant Biotechnology Journal, 2020 Summary Haplotype‐based breeding, a recent promising breeding approach to develop tailor‐made crop varieties, deals with identification of superior haplotypes and their deployment in breeding programmes.
P. Sinha +10 more
semanticscholar +1 more source
Frontiers in Genetics, 2021 The genomic region (~4 Mb) of the human major histocompatibility complex (MHC) on chromosome 6p21 is a prime model for the study and understanding of conserved polymorphic sequences (CPSs) and structural diversity of ancestral haplotypes (AHs)/conserved ...
Jerzy K. Kulski +3 more
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Optimizing Sequencing Resources in Genotyped Livestock Populations Using Linear Programming
Frontiers in Genetics, 2021 Low-cost genome-wide single-nucleotide polymorphisms (SNPs) are routinely used in animal breeding programs. Compared to SNP arrays, the use of whole-genome sequence data generated by the next-generation sequencing technologies (NGS) has great potential ...
Hao Cheng +4 more
doaj +1 more source