Results 41 to 50 of about 229,423 (345)

alpha-thalassemia, HbS, and beta-globin gene cluster haplotypes in two Afro-Uruguayan sub-populations from northern and southern Uruguay

Genetics and Molecular Biology, 2006
Hemoglobinopathies are the most common monogenic disorders worldwide; however, they have never been systematically studied from a genetic perspective in Uruguay. In this study, we determined the frequencies of hemoglobin variants in Afro-Uruguayans.
Julio A. da Luz, Mónica Sans, Elza Miyuki Kimura, Dulcinéia Martins Albuquerque, Maria de Fatima Sonati, Fernando Ferreira Costa   +5 more
doaj   +1 more source

Genetic Differentiation and Population Structure of Threatened Prunus africana Kalm. in Western Cameroon Using Molecular Markers

Diversity, 2020
Genetic diversity of species is an important baseline for the domestication process. In Cameroon, Prunus africana, an important and threatened medicinal tree, is among the priority species for domestication.
Justine G. Nzweundji, Ulrike Huewe, Nicolas Niemenak, Néhémie T. Donfagsiteli, Klaus Eimert   +4 more
doaj   +1 more source

Complex promoter and coding region beta 2-adrenergic receptor haplotypes alter receptor expression and predict in vivo responsiveness.

Proceedings of the National Academy of Sciences of the United States of America, 2000
The human beta(2)-adrenergic receptor gene has multiple single-nucleotide polymorphisms (SNPs), but the relevance of chromosomally phased SNPs (haplotypes) is not known.
Connie M. Drysdale, D. McGraw, Catharine B. Stack, J. Stephens, R. Judson, K. Nandabalan, Kevin Arnold, G. Ruaño, S. Liggett   +8 more
semanticscholar   +1 more source

Frecuencias alélicas, genotípicas y haplotípicas HLA-A, HLA-B, HLA-DRB1 en donantes fallecidos, Medellín, Colombia

Biomédica: revista del Instituto Nacional de Salud, 2007
Introducción. La caracterización genética del sistema HLA es de gran utilidad en estudios antropogenéticos, en la comprensión de mecanismos asociados a susceptibilidad o resistencia a diversas enfermedades, en los fenómenos inmunológicos durante el ...
Libia M. Rodríguez, Mabel C. Giraldo, Natalia García, Laura Velásquez, Sara C. París, Cristiam M. Álvarez, Luis F. García   +6 more
doaj   +1 more source

DNA barcoding elucidates the population genetic diversity of venomous cobra species (Reptilia: Elapidae) in Indo-Bangladesh region

Mitochondrial DNA. Part B. Resources, 2020
The DNA barcode data of venomous cobra species (Naja naja and Naja kaouthia) are limited in the global database, especially from India and Bangladesh. Owing to the rapid success of DNA barcoding for discriminating a variety of species around the world ...
Shantanu Kundu, Hmar Tlawmte Lalremsanga, Md. Mizanur Rahman, Md. Farid Ahsan, Lal Biakzuala, Vikas Kumar, Kailash Chandra, A. M. A. M. Zonaed Siddiki   +7 more
doaj   +1 more source

Functional Analysis of Haplotypes in Bovine PSAP Gene and Their Relationship with Beef Cattle Production Traits

Animals, 2020
The purpose of this study was to explore functional variants in the prosaposin (PSAP) three prime untranslated region (3’ UTR) and clarify the relationship between the variants and morphological traits.
Haidong Zhao, Mingli Wu, Xiaohua Yi, Xiaoqin Tang, Pingbo Chen, Shuhui Wang, Xiuzhu Sun   +6 more
doaj   +1 more source

Association of MAPT haplotypes with Alzheimer’s disease risk and MAPT brain gene expression levels

Alzheimer's Research & Therapy, 2014
IntroductionMAPT encodes for tau, the predominant component of neurofibrillary tangles that are neuropathological hallmarks of Alzheimer’s disease (AD).
M. Allen, Michaela Kachadoorian, Zachary S. Quicksall, F. Zou, H. Chai, C. Younkin, J. Crook, V. Pankratz, M. Carrasquillo, Siddharth Krishnan, Thuy Nguyen, Li Ma, Kimberly G. Malphrus, S. Lincoln, G. Bisceglio, C. Kolbert, J. Jen, Shubhabrata Mukherjee, J. Kauwe, P. Crane, J. Haines, R. Mayeux, M. Pericak-Vance, L. Farrer, G. Schellenberg, J. Parisi, R. Petersen, N. Graff-Radford, D. Dickson, S. Younkin, N. Ertekin-Taner   +30 more
semanticscholar   +1 more source

Asociación de variantes en genes de las proteínas desacoplantes con diabetes mellitus tipo 2 en una población del nordeste colombiano

Biomédica: revista del Instituto Nacional de Salud, 2009
Introducción. Las proteínas desacoplantes pertenecen a la familia de proteínas transportadoras de aniones que desacoplan la producción de ATP de la respiración mitocondrial, causando pérdida de protones a través de la membrana mitocondrial interna y ...
Liliana Franco-Hincapié, Constanza Elena Duque, María Victoria Parra, Natalia Gallego, Alberto Villegas, Andrés Ruiz-Linares, Gabriel Bedoya   +6 more
doaj   +1 more source

Mitochondrial DNA discriminates distinct population of two deadly snakes (Reptilia: Elapidae) in Northeast India

Mitochondrial DNA. Part B. Resources, 2020
The DNA data of Indian snakes are scanty in the global database, especially from the northeastern states. The present study generated the mitochondrial Cytochrome b gene information of two morphologically identified deadly elapid species from Mizoram ...
Shantanu Kundu, Hmar Tlawmte Lalremsanga, Kaomud Tyagi, Lal Biakzuala, Vikas Kumar, Kailash Chandra   +5 more
doaj   +1 more source

Homologous haplotypes, expression, genetic effects and geographic distribution of the wheat yield gene TaGW2

BMC Plant Biology, 2014
BackgroundTaGW2-6A, cloned in earlier research, strongly influences wheat grain width and TKW. Here, we mainly analyzed haplotypes of TaGW2-6B and their effects on TKW and interaction with haplotypes at TaGW2-6A.ResultsAbout 2.9 kb of the promoter ...
Lin Qin, C. Hao, Jian Hou, Yuquan Wang, Tian Li, Lanfen Wang, Zhengqiang Ma, Xueyong Zhang   +7 more
semanticscholar   +1 more source