Results 1 to 10 of about 57,032 (271)
Haptoglobin as a supplement in in vitro embryo culture: a tool for improving bovine embryo development and quality [PDF]
Biological ResearchBackground Recent studies have indicated the potential involvement of haptoglobin in a variety of events during mammalian reproduction, with previous research highlighting its efficacy in promoting porcine embryo development.
Karina Cañón-Beltrán +9 more
doaj +2 more sources
Low Level of Haptoglobin in Lupus [PDF]
Journal of Investigative Medicine High Impact Case Reports, 2017 Haptoglobin levels are measured in systematic lupus erythematosus patients as part of the workup for anemia, with low levels indicating hemolysis. Haptoglobin is an acute phase protein.
Homa Timlin MD, MSc +2 more
doaj +2 more sources
Neoplasia: An International Journal for Oncology Research, 2007 OBJECTIVE: This study was conducted to evaluate the prognostic significance of haptoglobin levels in the overall survival of patients presenting with various stages of epithelial ovarian cancer.
Changqing Zhao +7 more
doaj +2 more sources
The Cryo-EM structure of human CD163 bound to haptoglobin-hemoglobin reveals molecular mechanisms of hemoglobin scavenging [PDF]
Nature CommunicationsCD163, a macrophage-specific receptor, plays a critical role in scavenging hemoglobin released during hemolysis, protecting against oxidative effects of heme iron.
Anders Etzerodt +8 more
doaj +2 more sources
Haptoglobin buffers lipopolysaccharides to delay activation of NFκB [PDF]
Frontiers in ImmunologyIt has remained yet unclear which soluble factors regulate the anti-inflammatory macrophage phenotype observed in both homeostasis and tumourigenesis. We show here that haptoglobin, a major serum protein with elusive immunoregulatory properties, binds ...
Laura Zein +19 more
doaj +2 more sources
Immunohistochemical Expression of Haptoglobin in Skin Lesions of Hidradenitis Suppurativa [PDF]
LifeBackground: Meta-inflammation is a hallmark of hidradenitis suppurativa (HS). Research on meta-inflammation in HS is growing, but there is still no research on haptoglobin as an inflammatory protein in lesional HS skin.
Nessr Abu Rached +10 more
doaj +2 more sources
Haptoglobin-Conjugated Gold Nanoclusters as a Nanoantibiotic to Combat Bacteremia
Nanomaterials, 2022 Gold nanoclusters have revealed great potential as nanoantibiotics due to their superior chemical and physical characteristics. In this study, a peptide with 83 amino acids derived from haptoglobin was utilized as a surface ligand to synthesize gold ...
Hsiu-Yi Chu +6 more
doaj +1 more source
Role of haptoglobin in polycystic ovary syndrome (PCOS), obesity and disorders of glucose tolerance in premenopausal women. [PDF]
PLoS ONE, 2009 BackgroundHp(2) alleles of the haptoglobin alpha-chain polymorphism reduce the anti-oxidant properties and increase the pro-inflammatory actions of this acute-phase protein in a gene-dosage fashion. We hypothesized that the haptoglobin polymorphism might
Francisco Alvarez-Blasco +5 more
doaj +1 more source
Frontiers in Physiology, 2022 Background: In sickle cell disease (SCD), reduced bioavailability of endothelial NO and cGMP results in reduced expression of phosphodiesterase type 5 (PDE5), thus impairing the penile erection control mechanism and resulting in prolonged penile erection
Pamela da Silva Pereira +8 more
doaj +1 more source
Scientific Reports, 2021 Recent evidence supports involvement of the acute phase protein haptoglobin in numerous events during mammalian reproduction. The present study represents an in-depth investigation of haptoglobin expression and secretion in the porcine oviduct and uterus,
Francisco A. García-Vázquez +10 more
doaj +1 more source