Results 1 to 10 of about 37,781 (227)
Haptoglobin as a Biomarker [PDF]
Biochemistry (Moscow), Supplement Series B: Biomedical Chemistry, 2021 Haptoglobin (Hp) is a blood plasma glycoprotein that binds free hemoglobin (Hb) and plays a critical role in tissue protection and the prevention of oxidative damage. In addition, it has a number of regulatory functions. Haptoglobin is an acute phase protein, its concentration in plasma changes in pathology, and the test for its concentration is ...
O. K. Legina, S. N. Naryzny
openaire +5 more sources
Redox Report, 2001 Haptoglobin gene knockout mice and wild-type controls were infected with Plasmodium berghei ANKA or Plasmodium chabaudi. The peak parasitaemia and parasite burden were higher in Hp-/- mice than in Hp+/+ mice. The increase in spleen weight following malaria infection was smaller in Hp-/- mice than in Hp+/+ animals.
Hunt, N.H., Driussi, C., Sai-Kiang, L.
openaire +2 more sources
Turbidimetric Determination of Haptoglobin [PDF]
Clinical Chemistry and Laboratory Medicine, 1976 A specific, accurate and simple determination of haptoglobin is described with an antiserum against the antigenic determinants of the three haptoglobin phenotypes 1-1, 2-1 and 2-2. Antihaptoglobin is the determining factor in the formation of an antigen-antibody complex with maximal light absorption properties. Haptoglobin concentration is expressed as
Ramakers, J. M., Kreutzer, H. J. H.
openaire +2 more sources
The role of the host—Neutrophil biology
Periodontology 2000, EarlyView., 2023 Abstract Neutrophilic polymorphonuclear leukocytes (neutrophils) are myeloid cells packed with lysosomal granules (hence also called granulocytes) that contain a formidable antimicrobial arsenal. They are terminally differentiated cells that play a critical role in acute and chronic inflammation, as well as in the resolution of inflammation and wound ...
Iain L. C. Chapple +4 more
wiley +1 more source
Periodontology 2000, EarlyView., 2023 Abstract This review describes the origin and results of the prospective longitudinal study to test potential prognostic indicators for periodontal breakdown in a population deprived of regular dental care. Experimental gingivitis studies in individuals highly susceptible or highly resistant to periodontitis showed that bleeding on probing developed ...
Ubele Van der Velden
wiley +1 more source
Haptoglobins and Rheumatic Fever [PDF]
BMJ, 1966 The haptoglobins are polymorphic ?2-globulins which combine with free haemoglobin (Polonovski and Jayle, 1940). The usual method of haptoglobin typing with starch-gel electro phoresis reveals three phenotypes designated Hp 1-1, 2-1, and 2-2 (Smithies, 1955). A fourth phenotype in which no haptoglobin bands are detected has been classified Hp 0. Special
Elaine L. Pitt +4 more
openaire +3 more sources
Studies on the haptoglobin of eel. I. Purification of haptoglobin.
NIPPON SUISAN GAKKAISHI, 1975 Haptoglobin (Hp), a hemoglobin (Hb)-binding protein, was isolated and purified from eel serum by a method which consists of Sephadex G-25 gel filtration, DEAF-cellulose batch adsorption, DEAE-cellulose column chromatography, and Sephadex G-100 gel filtration. The Hp specimen thus purified was homogeneous in starch gel electrophoresis at pH 8.4.
Masaaki Kodama +2 more
openaire +2 more sources
American Journal of Hematology, EarlyView.Mixed autoimmune hemolytic anemia (AIHA) is a rare condition characterized by the presence of both warm and cold autoantibodies, often leading to severe, treatment‐resistant hemolysis. In this systematic review of 81 patients across 35 studies, the median age was 45 years with a notable female predominance.
Jeremy W. Jacobs +12 more
wiley +1 more source
Developmental Dynamics, EarlyView.Abstract Background CD163 is a scavenger receptor predominantly expressed on the surfaces of macrophages in various mammalian species and is a marker of anti‐inflammatory (M2‐like) macrophages. High density of CD163‐positive tumor‐associated macrophages (TAMs) is associated with worse prognosis in various patient tumors.
Yoichi Saito +9 more
wiley +1 more source
ESC Heart Failure, EarlyView.Flow chart illustrates the analysed patients as well as main baseline characteristics and outcomes comparing DanGer Shock‐like versus DanGer Shock‐unlike patients. The composite safety endpoint comprises severe bleeding, limb ischaemia, haemolysis, device failure, and worsening of aortic regurgitation. CS indicates cardiogenic shock.
Norman Mangner +10 more
wiley +1 more source