Results 31 to 40 of about 37,781 (227)

Concentration of C-reactive protein and haptoglobin in cows with subclinical endometritis [PDF]

Науковий вісник ветеринарної медицини, 2020
Acute phase proteins are blood components synthesized by hepatocytes, basic function of which is to defend the organism as part of the immune response to infl ammation, trauma, infection, stress, neoplasia.
Basarab T., Stefanyk V, Ivakhiv M., Niżański W   +3 more
doaj   +1 more source

Haptoglobin genotype and outcome after aneurysmal subarachnoid haemorrhage

Journal of Neurology Neurosurgery & Psychiatry, 2020
Objective After aneurysmal subarachnoid haemorrhage (aSAH), extracellular haemoglobin (Hb) in the subarachnoid space is bound by haptoglobin, neutralising Hb toxicity and helping its clearance. Two exons in the HP gene (encoding haptoglobin) exhibit copy
Matthew J Morton, I. Hostettler, N. Kazmi, V. Alg, S. Bonner, Martin M. Brown, A. Durnford, Ben Gaastra, P. Garland, J. Grieve, N. Kitchen, D. Walsh, A. Zolnourian, H. Houlden, Tom R. Gaunt, D. Bulters, D. Werring, I. Galea   +17 more
semanticscholar   +1 more source

Seasonal childhood anaemia in West Africa is associated with the haptoglobin 2-2 genotype.

PLoS Medicine, 2006
BackgroundAnaemia is a major cause of morbidity and mortality for children in Africa. The plasma protein haptoglobin (Hp) binds avidly to free haemoglobin released following malaria-induced haemolysis.
Sarah H Atkinson, Kirk Rockett, Giorgio Sirugo, Philip A Bejon, Anthony Fulford, Maria A O'Connell, Robin Bailey, Dominic P Kwiatkowski, Andrew M Prentice   +8 more
doaj   +1 more source

Assessment of the Acute Phase Response in Healthy and Injured Southern White Rhinoceros (Ceratotherium simum simum)

Frontiers in Veterinary Science, 2020
Acute phase reactants (APRs) have not been investigated in white rhinoceros (Ceratotherium simum). This study aimed to identify clinically useful APRs in this species.
Emma H. Hooijberg, Carolyn Cray, Gerhard Steenkamp, Peter Buss, Amelia Goddard, Michele Miller   +5 more
doaj   +1 more source

A genome-wide association study identifies rs2000999 as a strong genetic determinant of circulating haptoglobin levels.

PLoS ONE, 2012
Haptoglobin is an acute phase inflammatory marker. Its main function is to bind hemoglobin released from erythrocytes to aid its elimination, and thereby haptoglobin prevents the generation of reactive oxygen species in the blood. Haptoglobin levels have
Philippe Froguel, Ndeye Coumba Ndiaye, Amélie Bonnefond, Nabila Bouatia-Naji, Aurélie Dechaume, Gérard Siest, Bernard Herbeth, Mario Falchi, Leonardo Bottolo, Rosa-Maria Guéant-Rodriguez, Cécile Lecoeur, Michel R Langlois, Yann Labrune, Aimo Ruokonen, Said El Shamieh, Maria G Stathopoulou, Anita Morandi, Claudio Maffeis, David Meyre, Joris R Delanghe, Peter Jacobson, Lars Sjöström, Lena M S Carlsson, Andrew Walley, Paul Elliott, Marjo-Riita Jarvelin, George V Dedoussis, Sophie Visvikis-Siest   +27 more
doaj   +1 more source

Clinical Usefulness of Haptoglobin Levels to Evaluate Hemolysis in Recently Transfused Patients

Advances in Hematology, 2011
Introduction. Haptoglobin binds the globin portion of free hemoglobin. Serum haptoglobin measurement is used as a laboratory marker for the diagnosis of hemolytic anemia.
Shilpi Gupta, Kathleen Ahern, Fadi Nakhl, Frank Forte   +3 more
doaj   +1 more source

Antiphospholipid antibodies in healthy Serbian middle-aged subjects: Preliminary data [PDF]

Journal of Medical Biochemistry, 2022
Background: The investigation of the prevalence of the IgG and the IgM isotypes of anticardiolipin (aCL) and antib2glycoprotein I (ab2gpI) Abs in healthy Serbian middleaged subjects was the main goal of our study.
Bećarević Mirjana B., Jovičić Snežana, Ignjatović Svetlana D., Mirković Duško   +3 more
doaj   +1 more source

Haptoglobin administration into the subarachnoid space prevents hemoglobin-induced cerebral vasospasm.

Journal of Clinical Investigation, 2019
Delayed ischemic neurological deficit (DIND) is a major driver of adverse outcomes in patients with aneurysmal subarachnoid hemorrhage (aSAH) defining an unmet need for therapeutic development. Cell-free hemoglobin that is released from erythrocytes into
M. Hugelshofer, R. Buzzi, C. Schaer, H. Richter, Kevin Akeret, V. Anagnostakou, Leila Mahmoudi, Raphael Vaccani, Florence Vallelian, J. Deuel, P. Kronen, Z. Kulcsár, L. Regli, J. Baek, I. Pires, A. Palmer, M. Dennler, R. Humar, P. Buehler, P. Kircher, E. Keller, D. Schaer   +21 more
semanticscholar   +1 more source

Contribution of O-GlcNAc modification of NF-κB p65 in the attenuation of diabetes-induced haptoglobin expression in rat liver [PDF]

Archives of Biological Sciences, 2020
Haptoglobin (Hp) is a hemoglobin-binding protein that prevents free hemoglobin-induced tissue oxidative damage. In streptozotocin-induced diabetic rats, the initial elevation of Hp expression in the serum and liver tends to decrease with diabetes ...
Martinović Vesna I., Arambašić-Jovanović Jelena D., Bogojević Desanka B., Ivanović Anđelija S., Otašević Vesna M., Stančić Ana T., Grigorov Ilijana I.   +6 more
doaj   +1 more source

Dynamics of Salivary Adenosine Deaminase, Haptoglobin, and Cortisol in Lipopolysaccharide-Challenged Growing Pigs

Frontiers in Veterinary Science, 2021
Infectious and inflammatory conditions are common especially in growing pigs. Lipopolysaccharide (LPS) is an important antigenic structure of Gram-negative bacteria and can be used to induce inflammation experimentally.
Virpi Sali, Christina Veit, Anna Valros, Sami Junnikkala, Mari Heinonen, Mari Heinonen, Janicke Nordgreen   +6 more
doaj   +1 more source