Results 41 to 50 of about 65,853 (320)

Seasonal childhood anaemia in West Africa is associated with the haptoglobin 2-2 genotype.

open access: yesPLoS Medicine, 2006
BackgroundAnaemia is a major cause of morbidity and mortality for children in Africa. The plasma protein haptoglobin (Hp) binds avidly to free haemoglobin released following malaria-induced haemolysis.
Sarah H Atkinson   +8 more
doaj   +1 more source

Assessment of the Acute Phase Response in Healthy and Injured Southern White Rhinoceros (Ceratotherium simum simum)

open access: yesFrontiers in Veterinary Science, 2020
Acute phase reactants (APRs) have not been investigated in white rhinoceros (Ceratotherium simum). This study aimed to identify clinically useful APRs in this species.
Emma H. Hooijberg   +5 more
doaj   +1 more source

Haptoglobins and Rheumatic Fever [PDF]

open access: yesBMJ, 1966
The haptoglobins are polymorphic ?2-globulins which combine with free haemoglobin (Polonovski and Jayle, 1940). The usual method of haptoglobin typing with starch-gel electro phoresis reveals three phenotypes designated Hp 1-1, 2-1, and 2-2 (Smithies, 1955). A fourth phenotype in which no haptoglobin bands are detected has been classified Hp 0. Special
Elaine L. Pitt   +4 more
openaire   +3 more sources

A genome-wide association study identifies rs2000999 as a strong genetic determinant of circulating haptoglobin levels.

open access: yesPLoS ONE, 2012
Haptoglobin is an acute phase inflammatory marker. Its main function is to bind hemoglobin released from erythrocytes to aid its elimination, and thereby haptoglobin prevents the generation of reactive oxygen species in the blood. Haptoglobin levels have
Philippe Froguel   +27 more
doaj   +1 more source

Haptoglobin administration into the subarachnoid space prevents hemoglobin-induced cerebral vasospasm.

open access: yesJournal of Clinical Investigation, 2019
Delayed ischemic neurological deficit (DIND) is a major driver of adverse outcomes in patients with aneurysmal subarachnoid hemorrhage (aSAH) defining an unmet need for therapeutic development. Cell-free hemoglobin that is released from erythrocytes into
M. Hugelshofer   +21 more
semanticscholar   +1 more source

Clinical Usefulness of Haptoglobin Levels to Evaluate Hemolysis in Recently Transfused Patients

open access: yesAdvances in Hematology, 2011
Introduction. Haptoglobin binds the globin portion of free hemoglobin. Serum haptoglobin measurement is used as a laboratory marker for the diagnosis of hemolytic anemia.
Shilpi Gupta   +3 more
doaj   +1 more source

Changes in Serum Proteomic Profiles at Different Stages of Pregnancy Toxemia in Goats. [PDF]

open access: yesJ Vet Intern Med
ABSTRACT Background In human medicine, serum proteome profiles are used to differentiate metabolic diseases and evaluate their pathophysiology. Understanding the serum proteome profiles of goats with pregnancy toxemia might help identify the proteomes and pathways responsible for the development of this disease and improve diagnosis and treatment ...
Uztimür M, Ünal CN, Akpınar G.
europepmc   +2 more sources

Relationship between haptoglobin and serum amyloid A in milk and milk quality [PDF]

open access: yes, 2008
The objective of this study was to evaluate relationships between the presence in milk of the major bovine acute phase proteins, haptoglobin (Hp) and serum amyloid A (SAA), and milk quality parameters.
Bach Larsen, Lotte   +4 more
core   +1 more source

Studies of hepatic synthesis in vivo of plasma proteins, including orosomucoid, transferrin, α-antitrypsin, C8, and factor B [PDF]

open access: yes, 1980
Serum protein types were determined in eight recipients and donors in cases of hepatic homotransplantation. A change from recipient type to donor type was observed for factor B, C8, orosomucoid, haptoglobin, transferrin, α1-antitrypsin, C3 and C6, but ...
Alper   +29 more
core   +1 more source

Biosensor assay for determination of haptoglobin in bovine milk [PDF]

open access: yes, 2006
Despite more than 30 years of research into mastitis diagnostics, there are few alternatives to the somatic cell count (SCC) in practical use for identification of cows with subclinical mastitis.
Björk, Lennart   +3 more
core   +1 more source

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