Results 51 to 60 of about 37,781 (227)
Hemopexin and haptoglobin: allies against heme toxicity from hemoglobin not contenders
Frontiers in Physiology, 2015 The goal here is to describe our current understanding of heme metabolism and the deleterious effects of “free” heme on immunological processes, endothelial function, systemic inflammation, and various end-organ tissues (e.g., kidney, lung, liver, etc.),
Ann Smith, R. McCulloh
semanticscholar +1 more source
European Journal of Heart Failure, EarlyView.Kidney injury in heart failure‐related cardiogenic shock. AKI, acute kidney injury; CI, confidence interval; eCPR, extracorporeal cardiopulmonary resuscitation; eGFR, estimated glomerular filtration rate; HR, hazard ratio; OR, odds ratio; VA‐ECMO, veno‐arterial extracorporeal membrane oxygenation.
Jonas Sundermeyer +41 more
wiley +1 more source
JAMA Network Open, 2018 Key Points Question Is the haptoglobin genotype associated with cognition in African American adults with type 2 diabetes? Findings In this cohort study of 466 African American adults with type 2 diabetes, haptoglobin 1-1 carriers had the poorest ...
M. Beeri +13 more
semanticscholar +1 more source
Nihon Naika Gakkai Zasshi, 1963 Haptoglobin (Hpと略す)は溶血性疾患にて著明に減少するので,輸血後の微量の溶血の有無を検するため,各種疾患における輸血の前後にHpを測定した.同時に輸血によるHpの変動の意義を觀察するためと,溶血判定方法としてのHpの適否を検討するために動物実験をおこなつた. Hp測定法はLathemに準じて濾紙電気泳動法で行なった. (1) 種々の疾患20例に輸血前と輸血後2～4時間のHpを測定した結果,上昇10例,低下7例を認めた.特に20mg/dl以上の有意の変動を示す8例中2例のみに低下を認めた. (2) 動物にHpのhaemoglobin (Hb)結合能以内にHbを静注すると, Hpは一時上昇を認める.これはHpが新たに血中に補充されるものと考えられる.
Keisuke Toyama, Masahiro Hoshida
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Trends in resource utilization for new‐onset psychosis hospitalizations at children's hospitals
Journal of Hospital Medicine, EarlyView.Abstract Background Children with new‐onset psychosis often require hospitalization for medical evaluation. Objectives The goal of this study was to assess variations in the management of children with new‐onset psychosis and characterize trends in resource utilization.
Ankita Gupta +8 more
wiley +1 more source
Role of Haptoglobin in Health and Disease: A Focus on Diabetes
Clinical Diabetes, 2016 In Brief Prospective identification of individuals with diabetes who are at greatest risk for developing complications would have considerable public health importance by allowing appropriate resources to be focused on those who would benefit most from ...
Mark MacKellar, David J. Vigerust
semanticscholar +1 more source
Journal of Orthopaedic Research, EarlyView.ABSTRACT Posttraumatic osteoarthritis (PTOA) is a common sequela to anterior cruciate ligament (ACL) injury in humans and dogs. Identification of conserved targets between species may hasten biomarker identification and therapeutic development. To identify differentially regulated synovial fluid (SF) proteins in ACL injury, SF samples were collected ...
Sydney J. Womack +4 more
wiley +1 more source
Haptoglobin release by human adipose tissue in primary culture
Journal of Lipid Research, 2004 Haptoglobin is a putative adiposity marker because its concentration in blood is increased in obese humans. The present studies examined haptoglobin release by explants of adipose tissue in primary culture.
John N. Fain +2 more
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Haptoglobin Preserves Vascular Nitric Oxide Signaling during Hemolysis.
American Journal of Respiratory and Critical Care Medicine, 2016 RATIONALE Hemolysis occurs not only in conditions such as sickle cell disease and malaria but also during transfusion of stored blood, extracorporeal circulation, and sepsis.
C. Schaer +14 more
semanticscholar +1 more source
Haptoglobin Phenotypes in Epilepsy [PDF]
Clinical Chemistry, 2004 Seizures occur in ∼5% of people, and recur in >20% of that 5% (1)(2). The etiologies of most seizures are unknown, and head trauma is implicated in only 5–10% of cases (3). Blood or blood components, specifically iron, may be etiologically important; intracranial injection of hemoglobin (4), lysed erythrocytes (5), iron-containing proteins (5), or iron
Sayed M.H. Sadrzadeh +2 more
openaire +3 more sources